Failing Memory in Nonaffective Psychosis and Prolactin Response to 12.5 µg i.v. TRH.

The increase in plasma prolactin at 15 min following administration of 12.5 µg TRH i. v.

An abnormal relation between basal prolactin levels and prolactin response to 12.5 microg TRH i.v. in drug-naïve patients with first-episode schizophrenia.

At doses lower than those needed to stimulate prolactin release directly, TRH almost completely antagonizes the inhibitory effect of dopamine on prolactin release. We have previously reported that prolactin response to administration of 12.5 microg TRH i.