Incidence, risk factors, and clinical implications of postoperative blood in or near the resection cavity after glioma surgery.

Introduction: Postoperative hematomas that require reoperation are a serious, but uncommon complication to glioma surgery. However, smaller blood volumes are frequently observed, but their clinical significance is less known.

Research Question: What are the incidence rates, risk factors, and patient-reported outcomes of all measurable blood in or near the resection cavity on postoperative MRI in diffuse glioma patients?

Material And Methods: We manually segmented intradural and extradural blood from early postoperative MRI of 292 diffuse glioma resections.

Growth dynamics of untreated meningiomas.

Background: Knowledge about meningioma growth characteristics is needed for developing biologically rational follow-up routines. In this study of untreated meningiomas followed with repeated magnetic resonance imaging (MRI) scans, we studied growth dynamics and explored potential factors associated with tumor growth.

Methods: In a single-center cohort study, we included 235 adult patients with radiologically suspected intracranial meningioma and at least 3 MRI scans during follow-up.

Incidence, management, and outcome of incidental meningioma: what has happened in 10 years?

Purpose: The aim of this study was to study the use of brain scanning, and the subsequent findings of presumed incidental meningioma in two time periods, and to study differences in follow-up, treatment, and outcome.

Methods: Records of all performed CT and MRI of the brain during two time periods were retrospectively reviewed in search of patients with presumed incidental meningioma. These patients were further analyzed using medical health records, with the purpose to study clinical handling and outcome during a 3 year follow up.

Overview and recent advances in incidental meningioma.

Introduction: Meningioma has a prevalence around 1% in the population, and with the increasing use and availability of diagnostic imaging modalities, incidental meningiomas are increasingly detected. There is no clear consensus on their management, although several guidelines suggest firsthand active monitoring if no aggravating factors emerge. However, no collective guidelines on follow-up interval exist.

Is intracranial volume a risk factor for IDH-mutant low-grade glioma? A case-control study.

Purpose: Risk of cancer has been associated with body or organ size in several studies. We sought to investigate the relationship between intracranial volume (ICV) (as a proxy for lifetime maximum brain size) and risk of IDH-mutant low-grade glioma.

Methods: In a multicenter case-control study based on population-based data, we included 154 patients with IDH-mutant WHO grade 2 glioma and 995 healthy controls.

Brain infarction following meningioma surgery-incidence, risk factors, and impact on function, seizure risk, and patient-reported quality of life.

In this study, we seek to explore the incidence of and potential risk factors for postoperative infarctions after meningioma surgery, in addition to the possible association with new neurological deficits, seizures, and health-related quality of life (HRQoL). A single-center cohort study was conducted, where all patients operated for an intracranial meningioma at our institution between 2007 and 2020 were screened for inclusion. Clinical data were prospectively collected in a local tumor registry, and HRQoL was assessed using both generic and disease-specific instruments.

Methodological developments and practice in characterisation of unconventional and legacy waste.

Radioactive waste management requires planned and systematic actions to provide confidence that the entire system, processes and final products will satisfy given requirements for quality. The characterisation process is dependent on setting clear characterisation objectives and gathering the right information to underpin the decisions that need to be taken to manage the waste safely. This paper reviews experience of characterisation of waste generated from past nuclear activities that were not conducted in compliance consistent with current criteria, or from unexpected situations that were not planned for.

Brain infarctions after glioma surgery: prevalence, radiological characteristics and risk factors.

Background: Prevalence, radiological characteristics, and risk factors for peritumoral infarctions after glioma surgery are not much studied. In this study, we assessed shape, volume, and prevalence of peritumoral infarctions and investigated possible associated factors.

Methods: In a prospective single-center cohort study, we included all adult patients operated for diffuse gliomas from January 2007 to December 2018.

Building optimization into the process for decommissioning, remediation of legacy sites and facilities, and management of the wastes arising: results of an international workshop.

The coordinated organisation of decommissioning, remediation of legacy sites and facilities and management of the resultant waste materials has long been recognized as complex, involving technical challenges, safety and security issues, and a wide range of stakeholder interests. To help address these matters, an international workshop was held in November 2019 in Tromsø, jointly organized by the Norwegian Radiation and Nuclear Safety Authority and the Nuclear Energy Agency, in cooperation with the International Commission on Radiological Protection and the International Atomic Energy Agency. The workshop was the third in series hosted by DSA.

The impact of authors' medical specialty on publication patterns and published results of adjuvant radiotherapy for WHO grade 2 meningiomas-a systematic review.

Background: The role of adjuvant radiotherapy after gross total resection (GTR) of WHO grade 2 meningioma remains unclear, and conflicting results have been published. We hypothesized that authors' medical specialties could be associated with reported findings on the role of adjuvant radiotherapy after GTR of WHO grade 2 meningiomas.

Method: A systematic review was conducted in Embase and Medline databases, in addition to screening of all relevant bibliographies.

Prenatal exposure to Chernobyl fallout in Norway: neurological and developmental outcomes in a 25-year follow-up.

Ionizing radiation at high doses early in life may cause neurodevelopmental problems. Possible effects of lower doses are, however, controversial. We use carefully collected exposure data for Norway following the Chernobyl accident in April 1986 combined with population-based registries to assess long-term effects of fetal exposure on neurodevelopmental outcomes.

Addressing ecological effects of radiation on populations and ecosystems to improve protection of the environment against radiation: Agreed statements from a Consensus Symposium.

This paper reports the output of a consensus symposium organized by the International Union of Radioecology in November 2015. The symposium gathered an academically diverse group of 30 scientists to consider the still debated ecological impact of radiation on populations and ecosystems. Stimulated by the Chernobyl and Fukushima disasters' accidental contamination of the environment, there is increasing interest in developing environmental radiation protection frameworks.

The impact of the Fukushima nuclear accident on marine biota: retrospective assessment of the first year and perspectives.

An international study under the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) was performed to assess radiological impact of the nuclear accident at the Fukushima-Daiichi Nuclear Power Station (FDNPS) on the marine environment. This work constitutes the first international assessment of this type, drawing upon methodologies that incorporate the most up-to-date radioecological models and knowledge. To quantify the radiological impact on marine wildlife, a suite of state-of-the-art approaches to assess exposures to Fukushima derived radionuclides of marine biota, including predictive dynamic transfer modelling, was applied to a comprehensive dataset consisting of over 500 sediment, 6000 seawater and 5000 biota data points representative of the geographically relevant area during the first year after the accident.

On the potential for climate change impacts on marine anthropogenic radioactivity in the Arctic regions.

Current predictions as to the impacts of climate change in general and Arctic climate change in particular are such that a wide range of processes relevant to Arctic contaminants are potentially vulnerable. Of these, radioactive contaminants and the processes that govern their transport and fate may be particularly susceptible to the effects of a changing Arctic climate. This paper explores the potential changes in the physical system of the Arctic climate system as they are deducible from present day knowledge and model projections.

Application of an environmental impact assessment methodology to a site discharging low levels of radioactivity to a freshwater environment in Norway.

Significant shifts in opinion regarding environmental protection from ionising radiation have resulted in the development and availability of bespoke approaches for the assessment of impacts on wildlife from radioactive contaminants. The application of such assessment methodologies to actual situations, however, remains relatively limited. This paper describes the implementation of the ERICA Integrated Approach and associated tools within the context of routine discharges of radioactive materials to a freshwater environment.

Overview of dose assessment developments and the health of riverside residents close to the "Mayak" PA facilities, Russia.

The Norwegian Radiation Protection Authority (NRPA) has been involved in studies related to the Mayak PA and the consequences of activities undertaken at the site for a number of years. This paper strives to present an overview of past and present activities at the Mayak PA and subsequent developments in the quantification of health effects on local populations caused by discharges of radioactive waste into the Techa River. Assessments of doses to affected populations have relied on the development of dose reconstruction techniques for both external and internal doses.

Radiation-induced effects on plants and animals: findings of the United Nations Chernobyl Forum.

Several United Nations organizations sought to dispel the uncertainties and controversy that still exist concerning the effects of the Chernobyl accident. A Chernobyl Forum of international expertise was established to reach consensus on the environmental consequences and health effects attributable to radiation exposure arising from the accident. This review is a synopsis of the subgroup that examined the radiological effects to nonhuman biota within the 30-km Exclusion Zone.

Assessment of current exposure of the population living in the Techa River basin from radioactive releases of the Mayak facility.

Current doses arising from external and internal pathways have been estimated for the residents of two villages, Muslumovo and Brodokalmak, alongside the Techa River, which was contaminated by radioactive releases from the Mayak production facility. The dose estimates are based on numerous environmental measurements supplemented by further human whole body measurements and studies on occupational and dietary habits of Slavic and Turkish ethnic groups. Estimated doses arise mainly from use of the contaminated floodplains alongside the Techa River.

Surface ground contamination and soil vertical distribution of 137Cs around two underground nuclear explosion sites in the Asian Arctic, Russia.

Vertical distributions of 137Cs have been determined in vegetation-soil cores obtained from 30 different locations around two underground nuclear explosion sites--"Crystal" (event year - 1974) and "Kraton-3" (event year - 1978) in the Republic of Sakha (Yakutia), Russia. In 2001-2002, background levels of 137Cs surface contamination densities on control forest plots varied from 0.73 to 0.

Plutonium contamination in soils and sediments at Mayak PA, Russia.

The Mayak Production Association (Mayak PA) was established in the late 1940's to produce plutonium for the Soviet Nuclear Weapons Programme. In total, seven reactors and two reprocessing plants have been in operation. Today, the area comprises both military and civilian reactors as well as reprocessing and metallurgical plants.

Modelling of long-term behaviour of caesium and strontium radionuclides in the Arctic environment and human exposure.

In this paper a compartment model of the highly vulnerable Arctic terrestrial food chain "lichen-reindeer-man" is outlined. Based upon an analysis of measured (137)Cs and (90)Sr contents in lichen and reindeer meat from 1961 up to 2001, site specific model parameters for two regions in north-western Arctic Russia and for Kautokeino municipality in Arctic Norway have been determined. The dynamics of radionuclide activity concentrations in the "lichen-reindeer-man" food chain for all areas was satisfactorily described by a double exponential function with short-term and long-term effective ecological half-lives between 1-2 and 10-12 years, respectively, for both (137)Cs and (90)Sr.