Publications by authors named "Pennycuik P"

Volatile compounds from the fecal pellets deposited by a house mouse could be used for the purpose of communication with conspecifics. Analysis of volatiles from fresh and aged pellets by gas chromatography-mass spectrometry showed that many compounds were present and that ketones, alcohols, and carboxylic acids were the most common. Introducing volatiles from the fecal pellets of strange males into the territory of a singly housed male altered the site at which the resident mouse deposited most of its feces, and introducing the fecal pellets of a male mouse into the environment where it encountered a conspecific improved its success in an encounter with a stranger.

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The dermal-epidermal recombination technique was used to determine the site of action of the naked (N) locus in the skin of the mouse. The skin of athymic (nude) mice was used as a host site for growth of recombined epidermis and dermis from 13- and 14-day N/+ and +/+ embryos. Grafts that contained mutant epidermis lost their hair by 26 days after grafting (at the end of the first hair cycle) and again after 47 days (at the end of the second hair cycle); grafts that contained normal epidermis retained hair throughout the experiment.

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Earlier studies with the random-bred Quackenbush mouse strain showed that human-type diets based on linoleic acid-enriched foodstuffs derived from ruminants fed protected polyunsaturated oils have no detrimental effects on growth, reproduction or longevity. Tumour incidence and time of onset of tumour development have now been studied in the inbred, tumour-prone mouse strain C3H, in addition to growth, reproduction and longevity. Mice were fed a polyunsaturated human diet, a conventional human diet, or mouse cubes.

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The effects on the well-being of mice of feeding linoleic acid-enriched foodstuffs derived from ruminants receiving protected polyunsaturated oil were determined. Growth, reproductive productivity and longevity were compared in mice fed freeze-dried human diets containing either these products or the corresponding conventional ruminant-derived foods. A laboratory mouse pellet diet was used as a standard for the comparison.

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