Publications by authors named "Penny Liu"

Background: Spinal anesthesia (SA) is used in lumbar surgery, but initial adequate analgesia fails in some patients. In these cases, spinal redosing or conversion to general endotracheal anesthesia is required, both of which are detrimental to the patient experience and surgical workflow.

Methods: We reviewed cases of lumbar surgery performed under SA from 2017-2021.

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Article Synopsis
  • - The study investigates the impact of spinal anesthesia (SA) on reducing the use of multiple medications (polypharmacy) and opioid consumption in elderly patients (≥65 years) undergoing a specific spine surgery called transforaminal lumbar interbody fusion (TLIF) compared to general anesthesia (GA).
  • - Results show that patients receiving SA averaged 7.45 medications, significantly fewer than the 12.7 medications for those under GA, and had a much lower average opioid consumption (5.17 MME for SA vs. 20.2 MME for GA).
  • - The findings suggest that SA not only minimizes polypharmacy but may also lessen the need for opioid pain management; however, further studies are needed
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Spinal anesthesia (SA) is gaining recognition as a safe and efficacious regional alternative to general anesthesia for elective lumbar surgery. However, unfamiliarity with management issues related to its use has limited the adoption of awake spine surgery, despite its benefits. Few centers in the United States routinely offer SA for elective lumbar surgery, and a comprehensive workflow to standardize SA for lumbar surgery is lacking.

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Article Synopsis
  • Spinal anesthesia is safe for lumbar surgeries, even for patients with comorbidities like obesity, anxiety, and sleep apnea, challenging the notion that these factors increase complication risks.
  • A study analyzed 422 lumbar surgeries performed under spinal anesthesia, finding no significant differences in complications across various risk factor groups compared to a control group.
  • The findings suggest that spinal anesthesia can be a viable option for most patients with significant comorbidities, supporting its broader use in routine lumbar procedures.
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Background: Spinal anesthesia is safe and effective in lumbar surgeries, with numerous advantages over general anesthesia (GA). Nevertheless, 1 major concern preventing the widespread adoption of this anesthetic modality in spine surgeries is the potential for intraprocedural anesthetic failure, resulting in the need to convert to GA intraoperatively.

Objective: To present a novel additional prone dose algorithm for when a first spinal dose fails to achieve the necessary effect.

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Background: Spinal anesthesia (SA) is a safe and effective alternative to general endotracheal anesthesia (GEA) for lumbar surgery. Foremost among the reasons to avoid GEA is the desire to minimize postoperative cognitive dysfunction (POCD). Although POCD is a complex and multifactorial entity, the risk of its development has been associated with anesthetic modality and perioperative polypharmacy, among others.

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Objective: Postoperative urinary retention (POUR) is a common and vexing complication in elective spine surgery. Efficacious prevention strategies are still lacking, and existing studies focus primarily on identifying risk factors. Spinal anesthesia has become an attractive alternative to general anesthesia in elective lumbar surgery, with the potential of having a differential impact on POUR.

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Background: Spinal anesthesia is a safe and effective alternative to general anesthesia for patients undergoing lumbar spine surgery, and numerous reports have demonstrated its advantages. To the best of our knowledge, no group has specifically reported on the use of spinal anesthesia in thoracic-level spine surgeries because there is a hypothetical risk of injuring the conus medullaris at these levels. With the advantages of spinal anesthesia and the desire for many elderly patients to avoid general anesthesia, our group has uniquely explored the use of this modality on select patients with thoracic pathology requiring surgical intervention.

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Objective: The extreme elderly population (≥80 years of age) is expected to triple globally by 2050 and surgeries in this age group are likely to increase. Spinal anesthesia has emerged as a safe and effective alternative to general anesthesia in lumbar surgery and may particularly benefit extreme elderly patients concerned with post-operative cognitive dysfunction, poor physiological reserves, and polypharmacy. However, literature supporting its use in this population is lacking and there are potential challenges such as degenerative anatomy and medical comorbidities.

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The datasets presented here quantify and compare the relative carbon footprints emitted by general versus spinal anesthesia in patients undergoing single-level transforaminal lumbar interbody fusions (TLIFs). Data were retrospectively collected from electronic medical records of 100 consecutive patients who underwent a single-level TLIF from a single neurosurgeon at a U.S.

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Background: The U.S. health care sector produces approximately 10% of national greenhouse gas emissions, paradoxically harming human health.

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Objective: Spinal anesthesia (SA) is an alternative to general anesthesia (GA) for lumbar spine surgery, including complex instrumented fusion, although there are relatively few outcome data available. The authors discuss their experience using SA in a modern complex lumbar spine surgery practice to describe its utility and implementation.

Methods: Data from patients receiving SA for lumbar spine surgery by one surgeon from March 2017 to December 2020 were collected via a retrospective chart review.

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Background: Postoperative pain after transforaminal lumbar interbody fusion (TLIF) is a barrier to early mobility. Intraoperative local infiltration of anesthetic agents is standard practice to alleviate postoperative pain. Liposomal formulations may prolong the action of these anesthetic agents.

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