Synopsis of recent research by authors named "Pengzhong Shi"
- Pengzhong Shi's research primarily focuses on the development and characterization of novel materials for drug delivery systems, including protein-based microcapsules and porous carriers, highlighting the importance of physicochemical properties like stiffness and degradation sensitivity on cellular uptake and drug release mechanisms.
- Significant findings from recent studies include the demonstration that stiffness in protein-based microcapsules affects dendritic cell uptake and the development of a hexahistidine-metal assembly for protecting therapeutic proteins from degradation, facilitating their delivery in acute liver injury models.
- Shi also explores the innovative design of covalent organic frameworks (COFs) and their applications as fluorescent sensors, in addition to creating a universal method for fabricating diverse protein capsules for varied applications in drug delivery, catalysis, and tissue engineering.
