Publications by authors named "Pengying Yuan"

Background: Zhengsui Wan (ZSW) is a commonly used traditional Chinese medicine formula for treating Acute Lymphatic Leukemia (ALL) in our institution, and it has shown potential efficacy. However, its mechanism of action (MoA) remains unclear. In this study, we systematically explored the ZSW in ALL (in vitro and in vivo) using network pharmacology and molecular docking techniques.

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Article Synopsis
  • Recent studies show a potential link between metabolites, immune cell types, and the risk of lymphoma, but how these factors interact still needs clarification.
  • The research utilized two-sample Mendelian randomization and large-scale genomic data to analyze the relationship between 1400 metabolites, 731 immune cell types, and different lymphoma subtypes.
  • The findings revealed bidirectional causal relationships between specific metabolites and lymphomas, as well as mediating roles of certain immune cells in these associations.
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