Synopsis of recent research by authors named "Pengyan Xia"
- Pengyan Xia's recent research emphasizes the interplay between the gut microbiome, immune response, and metabolic diseases, highlighting mechanisms such as time-restricted feeding's effects on metabolic dysfunction and the role of gut microbes like Ruminococcus torques.
- Studies on non-alcoholic steatohepatitis (NASH) reveal a critical role of lipid metabolites such as sphingosine d18:1 and their impact on macrophage function, indicating potential targets for therapeutic interventions.
- Xia's work also explores novel inflammasome pathways, identifying new receptors and negative regulators like Nur77 and adipose triglyceride lipase, which enhance understanding of their roles in immune response and inflammation, thereby informing potential treatment strategies.
