Selective Photocatalytic Conversion of CO to Ethanol via Unsaturated Cu-O Domains.

Enhancing the selectivity of photocatalytic CO reduction to valuable multicarbon (C) products remains a significant challenge in green synthetic chemistry. Here, we present a dual-center strategy for metal oxides that boosts the photochemical conversion of CO to ethanol by regulating the coordination number of metal and oxygen sites. Notably, CuO catalysts rich in low-coordinated Cu-O domains have achieved nearly perfect ethanol selectivity (96.

Definition of regulatory elements and transcription factors controlling porcine immune cell gene expression at single cell resolution using single nucleus ATAC-seq.

The transcriptome of porcine peripheral blood mononuclear cells (PBMC) at single cell (sc) resolution is well described, but little is understood about the cis-regulatory mechanism behind scPBMC gene expression. Here, we profiled the open chromatin landscape of porcine PBMC that define cis-regulatory elements and mechanism contributing to the transcription using single nucleus ATAC sequencing (snATAC-seq). Approximately 22 % of the identified peaks overlapped with annotated transcription start sites (TSS).