Publications by authors named "Pengweilin Ji"
Environ Int
September 2024
Article Synopsis
- - Triclocarban (TCC) is an antimicrobial ingredient found in many household and personal care products, raising concerns about its health risks, particularly its potential neurotoxicity since it can cross the blood-brain barrier.
- - The study found that mice exposed to TCC exhibited anxiety-like behaviors and showed disruptions in brain functions, including altered protein activities related to neurodegenerative disorders and mitochondrial dysfunction affecting energy metabolism.
- - Mechanistic investigations indicated that TCC exposure led to increased mitochondrial reactive oxygen species (mROS) and neural cell apoptosis, suggesting that these factors play significant roles in TCC-induced neurotoxicity, potentially linking it to the development of neurodegenerative diseases.
