Publications by authors named "Pengshuai Li"

Article Synopsis
  • - This study reveals that elastin (Eln), an extracellular matrix protein, can promote the proliferation of mouse pulmonary artery smooth muscle cells (mPASMCs) and its expression increases significantly under hypoxic conditions.
  • - When Eln expression was inhibited using siRNA, there was a notable reduction in key proteins involved in cell growth (PCNA, Cyclin A, and Cyclin D), reversing the proliferation driven by hypoxia.
  • - The research also highlights that the effects of hypoxia on Eln and mPASMCs proliferation are linked to the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway, suggesting Eln's crucial role in hypoxic
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Zearalenone (ZEN) is a mycotoxin produced by various Fusarium strains, that is present in food and feed raw materials worldwide, causing toxicity effects in animals and humans. This research aimed to explore the toxicokinetics of ZEN on female Dezhou donkeys following a single oral exposure dosage of 2 mg/kg BW (body weight). The sample collection of donkeys plasma was carried out at 0, 5, 10, 15, 20, 30, 45, 60, 90 min, 2 h, 2.

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