BR signalling haplotypes contribute to indica-japonica differentiation for grain yield and quality in rice.

The functional difference of natural variations in conserved BR signalling genes and the genetic basis of rice indica-japonica differentiation are important yet unknown. Here, we discovered natural variations of the four key components (OsBRI1, OsBAK1, OsGSK3 and OsBZR1) in BR signalling pathway by GWAS using an indicator of indica-japonica differentiation in rice. Two major BR signalling haplotypes (BSHs), caused by co-selected variations of the four genetically unlinked genes, were identified to be highly differentiated between rice subspecies.

The quantitative trait locus GWY10 controls rice grain width and yield.

A rice grain width and yield quantitative trait locus increases grain yield in near-isogenic lines and gene-edited lines and improves grain appearance and milling quality.

Insertion of a miniature inverted-repeat transposable element into the promoter of OsTCP4 results in more tillers and a lower grain size in rice.

A class I PCF type protein, TCP4, was identified as a transcription factor associated with both grain size and tillering through a DNA pull-down-MS assay combined with a genome-wide association study. This transcription factor was found to have a significant role in the variations among the 533 rice accessions, dividing them into two main subspecies. A Tourist-like miniature inverted-repeat transposable element (MITE) was discovered in the promoter of TCP4 in japonica/geng accessions (TCP4M+), which was found to suppress the expression of TCP4 at the transcriptional level.

Assessment of quality of life in patients treated for orbital fractures.

Purpose: This study aimed to assess the quality of life (QOL), before and after surgery, of patients who underwent open reduction and internal fixation for orbital fractures.

Study Design: A prospective study.

Participants And Setting: The self-report outcome measures of 50 patients treated at the Department of Oral and Maxillofacial Surgery of the Second Affiliated Hospital of Jiamusi University from January 2016 to June 2019 were prospectively collected.

OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice.

Grain chalkiness, an undesirable trait caused by complex factors, has great negative impacts on the quality and economic value of rice. However, little is known about the regulatory mechanism of grain chalkiness, particularly the effect of endoplasmic reticulum (ER) stress. Here, a genome-wide association study (GWAS) reveals that the transcription factor OsbZIP60 is a vital regulator of rice grain chalkiness.

The identification of grain size genes by RapMap reveals directional selection during rice domestication.

Cloning quantitative trait locus (QTL) is time consuming and laborious, which hinders the understanding of natural variation and genetic diversity. Here, we introduce RapMap, a method for rapid multi-QTL mapping by employing F gradient populations (FGPs) constructed by minor-phenotypic-difference accessions. The co-segregation standard of the single-locus genetic models ensures simultaneous integration of a three-in-one framework in RapMap i.