A New Species of the Genus Oshima, 1919 (Cypriniformes: Cyprinidae) from the Dabie Mountains.

Oshima, 1919, a cyprinid genus of Cyprinidae in southern China and currently comprises 26 valid species. In this study, we describe from the Dabie Mountains, China. This new species differs from its congeners by the following combination of characters: The second primary vertical bar (PB2) is situated beneath the anterior origin of the dorsal fin in females and subadult males.

A case of a neonatal cardiac tumor with ventricular tachycardia undergoing emergency surgery.

Background: Cardiac tumors in children are rare and usually have no obvious clinical symptoms. However, a small number of children may experience serious conditions such as arrhythmia, heart obstruction, and even death. When severe arrhythmia cannot be controlled by conservative treatment, surgical intervention is needed.

Regulates Developmental and Immune Trade-Offs Induced by Priming in .

The red palm weevil (RPW) is an invasive pest that causes devastating damage to a variety of palm plants, which exhibit specific immune priming to (Bt). However, immune priming in RPW may incur a high fitness cost, and its molecular signaling pathways have not yet been reported. Here, we investigated the effect of Bt priming on RPW development and subsequently analyzed the hormonal and immune-related molecular pathways influencing the fitness cost induced by Bt priming.

Spatiotemporal prediction of alpine wetlands under multi-climate scenarios in the west of Sichuan, China.

Background: The alpine wetlands in western Sichuan are distributed along the eastern section of the Qinghai-Tibet Plateau (QTP), where the ecological environment is fragile and highly sensitive to global climate change. These wetlands are already experiencing severe ecological and environmental issues, such as drought, retrogressive succession, and desertification. However, due to the limitations of computational models, previous studies have been unable to adequately understand the spatiotemporal change trends of these alpine wetlands.

Exon 1 methylation status of CDH13 is associated with decreased overall survival and distant metastasis in patients with postoperative colorectal cancer.

Background: Cadherin 13 (CDH13) is a member of the cadherin superfamily that exerts tumor-suppressive effects on cancers derived from epithelial cells. Although hypermethylation of CDH13 promoter has been reported in various cancers, its prognostic value for colorectal cancer (CRC) is still controversial. The methylation alterations of CDH13 within exon 1 have not yet been investigated.

Soft hydrogel semiconductors with augmented biointeractive functions.

Hydrogels, known for their mechanical and chemical similarity to biological tissues, are widely used in biotechnologies, whereas semiconductors provide advanced electronic and optoelectronic functionalities such as signal amplification, sensing, and photomodulation. Combining semiconducting properties with hydrogel designs can enhance biointeractive functions and intimacy at biointerfaces, but this is challenging owing to the low hydrophilicity of polymer semiconductors. We developed a solvent affinity-induced assembly method that incorporates water-insoluble polymer semiconductors into double-network hydrogels.

Beyond 25 years of biomedical innovation in nano-bioelectronics.

Nano-bioelectronics, which blend the precision of nanotechnology with the complexity of biological systems, are evolving with innovations such as silicon nanowires, carbon nanotubes, and graphene. These elements serve applications from biochemical sensing to brain-machine interfacing. This review examines nano-bioelectronics' role in advancing biomedical interventions and discusses their potential in environmental monitoring, agricultural productivity, energy efficiency, and creative fields.

A Novel Joint Motion Compensation Algorithm for ISAR Imaging Based on Entropy Minimization.

Space targets move in orbit at a very high speed, so in order to obtain high-quality imaging, high-speed motion compensation (HSMC) and translational motion compensation (TMC) are required. HSMC and TMC are usually adjacent, and the residual error of HSMC will reduce the accuracy of TMC. At the same time, under the condition of low signal-to-noise ratio (SNR), the accuracy of HSMC and TMC will also decrease, which brings challenges to high-quality ISAR imaging.

Active biointegrated living electronics for managing inflammation.

Seamless interfaces between electronic devices and biological tissues stand to revolutionize disease diagnosis and treatment. However, biological and biomechanical disparities between synthetic materials and living tissues present challenges at bioelectrical signal transduction interfaces. We introduce the active biointegrated living electronics (ABLE) platform, encompassing capabilities across the biogenic, biomechanical, and bioelectrical properties simultaneously.

Serratia plymuthica HK9-3 enhances tomato resistance against Phytophthora capsici by modulating antioxidant defense systems and rhizosphere micro-ecological condition.

Tomatoes are frequently challenged by various pathogens, among which Phytophthora capsici (P. capsici) is a destructive soil-borne pathogen that seriously threatens the safe production of tomatoes. Plant growth-promoting rhizobacteria (PGPR) positively induced plant resistance against multiple pathogens.

Exploring Present and Future Directions in Nano-Enhanced Optoelectronic Neuromodulation.

Electrical neuromodulation has achieved significant translational advancements, including the development of deep brain stimulators for managing neural disorders and vagus nerve stimulators for seizure treatment. Optoelectronics, in contrast to wired electrical systems, offers the leadless feature that guides multisite and high spatiotemporal neural system targeting, ensuring high specificity and precision in translational therapies known as "photoelectroceuticals". This Account provides a concise overview of developments in novel optoelectronic nanomaterials that are engineered through innovative molecular, chemical, and nanostructure designs to facilitate neural interfacing with high efficiency and minimally invasive implantation.

Finite element method-based study for spinal vibration characteristics of the scoliosis and kyphosis lumbar spine to whole-body vibration under a compressive follower preload.

Purpose: To analyze the dynamic response of the lumbosacral vertebrae structure of a scoliosis spine and a kyphosis spine under whole-body vibration.

Methods: Typical Lenke4 (kyphosis) and Lenke3 (scoliosis) spinal columns were used as research objects. A finite element model of the lumbosacral vertebrae segment was established and validated based on CT scanning images.

A nomogram based on TFE3 IHC results and clinical factors as a preliminary screening scheme for TFE3-rearranged renal cell carcinoma.

Background: TFE3 immunohistochemistry (TFE3-IHC) is controversial in the diagnosis of TFE3-rearranged renal cell carcinoma (TFE3-rearranged RCC). This study is to investigate the accuracy and sensitivity of IHC and establish a predictive model to diagnose TFE3-rearranged RCC.

Methods: Retrospective analysis was performed by collecting IHC and fluorescence in situ hybridization (FISH) results from 228 patients.

LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.

The tumour microenvironment (TME) drives bladder cancer (BLCA) progression. Targeting the TME has emerged as a promising strategy for BLCA treatment in recent years. Furthermore, checkpoint blockade therapies are only beneficial for a minority of patients with BLCA, and drug resistance is a barrier to achieving significant clinical effects of anti-programmed cell death protein-1 (PD-1)/programmed death protein ligand-1 (PD-L1) therapy.

Biofilm formation of Hafnia paralvei induced by c-di-GMP through facilitating bcsB gene expression promotes spoilage of Yellow River carp (Cyprinus carpio).

Hafnia paralvei, a Gram-negative foodborne pathogen, is found ubiquitously in various aquatic animals and seafoods, which can form biofilm as a dominant virulence factor that contributes to its pathogenesis. However, the biofilm formation mechanism of H. paralvei and its effect on food spoilage has not been fully characterized.

Monolithic silicon for high spatiotemporal translational photostimulation.

Electrode-based electrical stimulation underpins several clinical bioelectronic devices, including deep-brain stimulators and cardiac pacemakers. However, leadless multisite stimulation is constrained by the technical difficulties and spatial-access limitations of electrode arrays. Optogenetics offers optically controlled random access with high spatiotemporal capabilities, but clinical translation poses challenges.

Estuarine hydrodynamic processes driving the molecular changes of terrestrial dissolved organic nitrogen: From mixing to biological modification.

Estuaries receive substantial amounts of terrestrial dissolved organic nitrogen (tDON), which will be transported from the freshwater to the oceanic terminus through vigorous exchange processes. However, the intricate migration and transformation dynamics of tDON during this transportation, particularly at a molecular level, remain constrained. To address this knowledge gap, Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was used for the analysis of DON molecular composition in the Pearl River Estuary (PRE), a river-dominated estuarine system influenced by intensified anthropogenic activities in southern China.

Coulomb blockade and Coulomb staircases in CoBi nanoislands on SrTiO(001).

We successfully fabricated two-dimensional metallic CoBi nanoislands on SrTiO(001) substrate by molecular beam epitaxy, and systematically investigated their electronic structures by scanning tunneling microscopy and spectroscopyat 4.2 K. Coulomb blockade and Coulomb staircases with discrete and well-separated levels are observed for the individual nanoisland, which is attributed to single-electron tunneling via two tunnel junction barriers.

Co-exposure of nanoplastics and arsenic causes neurotoxicity in zebrafish (Danio rerio) through disrupting homeostasis of microbiota-intestine-brain axis.

Nanoplastics (NPs) and arsenic (As) are toxic pollutants prevalent on the earth and have gained considerable attention in recent decades. Although numerous studies reported NPs and As can cause neurotoxicity there are still significant knowledge gaps in illustrating their combined toxicity and its mechanism. In this study, the co-exposure of environmentally relevant concentrations of NPs and As caused neurobehavioral toxicity in zebrafish, as evidenced by reduced swimming ability, anxiety and impaired short-term learning memory.

Displacement Measurement Method Based on Double-Arrowhead Auxetic Tubular Structure.

This research paper introduces an innovative technique for measuring displacement using auxetic tubular structure (ATS). The proposed displacement measurement method is based on tubular structures with a negative Poisson's ratio. It capitalizes on the underlying principle that the elastic deformation-induced change in transmittance of the ATS can be translated into a corresponding modification in the output current of the solar cell.

Selenium reduces hepatopancreas lipid accumulation of grass carp () fed high-fat diet via lipophagy activation.

It has been reported that selenium (Se) can reduce hepatopancreas lipid accumulation induced by high-fat diet. However, its mechanism is still unknown. This study aims to investigate the specific mechanisms by which Se alleviates high-fat diet-induced lipid accumulation.

Using Vertically Aligned Carbon Nanofiber Arrays on Rigid or Flexible Substrates for Delivery of Biomolecules and Dyes to Plants.

The delivery of biomolecules and impermeable dyes to intact plants is a major challenge. Nanomaterials are up-and-coming tools for the delivery of DNA to plants. As exciting as these new tools are, they have yet to be widely applied.

Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma.

Background: Clear cell renal cell carcinoma (ccRCC) is a highly invasive and metastatic subtype of kidney malignancy and is correlated with metabolic reprogramming for adaptation to the tumor microenvironment comprising infiltrated immune cells and immunomodulatory molecules. The role of immune cells in the tumor microenvironment (TME) and their association with abnormal fatty acids metabolism in ccRCC remains poorly understood.

Method: RNA-seq and clinical data of KIRC from The Cancer Genome Atlas (TCGA) and E-MTAB-1980 from the ArrayExpress dataset.