Publications by authors named "Pengju Chen"

We study the chaotic motion of a semi-classical optomechanical system coupled to a non-Markovian environment with a finite correlation time. By studying the emergence of chaos using the Lyapunov exponent with the changing non-Markovian parameter, we show that the non-Markovian environment can significantly enhance chaos. It is observed that a non-Markovian environment characterized by the Ornstein-Uhlenbeck type noise can modify the generation of chaos with different environmental memory times.

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Article Synopsis
  • Pigeon Newcastle disease (ND) is an infectious disease caused by the Newcastle disease virus, primarily affecting pigeons and doves, with genotype VI being a significant contributor.
  • A study in China identified eight NDV strains that displayed mesogenic characteristics and showed a high genetic similarity to reference strains, indicating their potential danger.
  • The prevalence of these strains, especially sub-genotype VI.2.1.1.2.2, has been increasing since 2011, underlining the urgent need to monitor NDV outbreaks in pigeons in China.
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Introduction: Hyperuricemia is widespread in humans and birds which is a necessary physiological factor leading to gout. Studies have shown an inextricable relationship between gut microbiota and hyperuricemia. This study explored the association between intestinal flora and hyperuricemia in Goslings.

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Salmonella enterica serotype Typhimurium, an important foodborne pathogen with high adaptability to the host's internal and external survival environment, seriously threatens public health. Therefore, to understand the mechanism underlying the high adaptability, this study investigated the transcription factor BolA by constructing BolA deletion strain 269△BolA, complemented strain 269BolAR and overexpression strain 269BolA+ based on WT269. BolA significantly inhibited motility; at 6 h, the BolA overexpression strain (269BolA+) showed 91.

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Background: Induction chemotherapy combined with neoadjuvant chemoradiotherapy has been recommended for patients with high-risk, locally advanced rectal cancer. However, the benefit of more intensive total neoadjuvant treatment (TNT) is unknown. This study aimed to assess the safety and efficacy of induction chemotherapy combined with chemoradiotherapy and consolidation chemotherapy for magnetic resonance imaging-stratified high-risk rectal cancer.

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The coexistence of and in the plasmid of has been widely reported and such strains have been mainly isolated from animal and human feces. However, few reports have focused on the genetic diversity of -carrying chromosomes and -carrying plasmids in isolates from lesion-bearing animal organs. This study investigated the genetic characteristics of chromosome-mediated and plasmid-mediated in isolated from lesion-bearing animal organs.

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Attenuated Salmonella Typhimurium is a promising antigen delivery system for live vaccines such as polysaccharides. The length of polysaccharides is a well-known key factor in modulating the immune response induced by glycoconjugates. However, the relationship between the length of Lipopolysaccharide (LPS) O-antigen (OAg) and the immunogenicity of S.

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Background: Approximately 10% of stage I colorectal cancer (CRC) patients experience unfavorable clinical outcomes after surgery. However, little is known about the subset of stage I patients who are predisposed to high risk of recurrence or death. Previous evidence was limited by small sample sizes and lack of validation.

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Deep vein thrombosis (DVT) is a common disease in vascular surgery. In recent study, microRNA (miRNA) plays a regulatory role in function of Endothelial progenitor cells (EPCs), which showed promising therapeutic choice for DVT. However, the function of miR-143-3p in EPCs remains incomplete.

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Background: Prognostic and pathologic risk factors typically guide clinicians and patients in their choice of surveillance or adjuvant chemotherapy when managing high-risk stage II colon cancer. However, variations in treatment and outcomes in patients with stage II colon cancer remain.

Objective: This study aimed to assess the survival benefits of treatments concordant with suggested therapeutic options from Watson for Oncology, a clinical decision support system.

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Replicated multiple scale species distribution models (SDMs) have become increasingly important to identify the correct variables determining species distribution and their influences on ecological responses. This study explores multi-scale habitat relationships of the snow leopard () in two study areas on the Qinghai-Tibetan Plateau of western China. Our primary objectives were to evaluate the degree to which snow leopard habitat relationships, expressed by predictors, scales of response, and magnitude of effects, were consistent across study areas or locally landcape-specific.

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Circular RNAs (circRNAs) are an emerging class of non-coding RNAs, identified to participate in multiple malignancies. Nevertheless, the clinical significance, biological function, and regulatory mechanisms of circRNAs in colon cancer (CC) remain largely unclear. In this study, the circRNA expression profile in CC and matched normal tissues was analyzed using circRNA microarrays.

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Background: Heterogeneity with respect to recurrence and survival in high-risk stage II colon cancer patients still exists, and further classification is urgently required. This study aimed to ascertain the prognostic value of DNA ploidy, stroma-tumour fraction and nucleotyping in the prognosis of high-risk stage II colon cancer.

Methods: A total of 188 high-risk stage II colon cancer patients received radical surgery in Peking University Cancer Hospital, from 2009 to 2015.

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Article Synopsis
  • This study investigates the complexity of bitterness in Traditional Chinese Medicine (TCM) by mixing various bitter compounds to understand their superposition effects.
  • The research involved evaluating bitterness using traditional taste panels and an electronic tongue, leading to the establishment of bitterness-concentration models based on Weibull and logarithmic functions.
  • Results demonstrated that the bitterness of the mixtures aligns with these models, revealing that the influence of the original or "mother" liquor on the overall bitterness diminishes as the concentration of additive substances increases.
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Background: Malignant bowel obstruction (MBO) is a common event for end-stage gastrointestinal cancer patients. Previous studies had demonstrated manifestations and clinical management of MBO with mixed malignancies. There still lack reports of the surgical treatment of MBO.

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This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.

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'Quality evaluation based on color grading' is one of the features used in Chinese medicine discrimination. In order to assess the feasibility of electronic eye (E-eye) in implementing 'quality evaluation based on color grading', the present study applied an IRIS VA400 E-eye to test 58 batches of Corni Fructus samples. Their optical data were acquired and combined with their corresponding classes.

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The lungs are the second most common site of metastasis for colorectal cancer (CRC) after the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to colon cancer. In China, the proportion of rectal cancer cases is around 50%, much higher than that in Western countries (nearly 30%).

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To understand the effect of forests and wetlands on air quality, the PM and PM concentration and meteorological data were collected in the forest and wetland in the Beijing Olympic Forest Park in China from May 2106 to May 2017. The blocking rates of forest and wetland to PMs were calculated under different air quality grades which were divided into six levels base on a technical regulation. And we have got three main conclusions.

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Habitat evaluation constitutes an important and fundamental step in the management of wildlife populations and conservation policy planning. Geographic information system (GIS) and species presence data provide the means by which such evaluation can be done. Maximum Entropy (MaxEnt) is widely used in habitat suitability modeling due to its power of accuracy and additional descriptive properties.

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Objective: To investigate the effect of adjuvant chemotherapy on the prognosis of stage II( colon cancer patients with high risk factors.

Methods: Clinicopathological and follow-up data of stage II( colon cancer patients undergoing radical surgery from January 2001 to March 2012 at Gastrointestinal Cancer Center of Peking University Cancer Hospital were retrospectively analyzed. The effect of adjuvant chemotherapy (within postoperative 2 month, fluorine uracil as main drugs) on the prognosis of high-risk patients was analyzed.

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Objective: To explore the clinicopathological characteristics and prognosis of colon cancer patients with extremely elevated serum carcinoembryonic antigen(CEA) level before operation(>50 μg/L).

Methods: Clinicopathological and follow-up data of 1250 patients with colonic adenocarcinoma undergoing primary tumor resection between January 2001 and December 2011 were retrospectively analyzed. All the patients were divided into three groups according to the preoperative serum CEA levels as normal group (0-5 μg/L, 721 cases), elevated group(5-50 μg/L, 408 cases) and extremely elevated(>50 μg/L, 121 cases).

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The diagnosis and treatment of colorectal cancer is one of the main diseases of gastrointestinal surgeons. It is very important to master the adjuvant chemotherapy of colorectal cancer for gastrointestinal surgeons. In recent years, with the development of a number of clinical trials and the appearance of new drugs, fluorouracil combined with oxaliplatin had been established as the standard regimen of adjuvant chemotherapy for colorectal cancer.

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Objective: To investigate the survival and prognostic factors of stage 0 to III rectal cancer in 10 years.

Methods: Clinical data and follow-up of 856 rectal cancer patients with stage 0-III underwent curative surgery from January 2000 to December 2010 were retrospective analyzed. There were 470 male and 386 female patients, with a mean age of (58 ± 12) years.

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Objective: The purpose of this study is to evaluate whether adjuvant chemotherapy could bring oncologic benefit to all patients who underwent neoadjuvant radiotherapy (30Gy/10f).

Methods: Rectal cancer patients receiving preoperative radiotherapy between July 2002 and April 2009 were retrospectively identified.

Results: A total of 225 patients were enrolled in this study.

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