Publications by authors named "Penghui Fan"

In this paper, an event-triggered adaptive neural prescribed performance admittance control (ETANPPAC) scheme is proposed to control the constrained robotic systems without velocity sensors. To ensure compliance during human-robot interaction, the reference trajectory is obtained by reshaping the desired trajectory for the robotic systems based on the admittance relationship, where a saturation function is used to constrain the reference trajectory, avoiding excessive contact forces that could render the trajectory inexecutable. Moreover, a barrier Lyapunov function is used to constrain the tracking errors for prescribed performance, where a velocity observer and a radial basis function neural network are designed to estimate the velocity and the uncertainty of the robotic systems, respectively, to enhance control performance.

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What Is Already Known About This Topic?: Foodborne diseases, representing significant food safety and public health challenges globally, are not well-documented in terms of incidence, particularly for cases characterized by acute gastroenteritis (AGI) in China.

What Is Added By This Report?: This study developed a pyramid model to estimate the incidence of five pathogens, stratified by gender and age. The estimated incidences per 100,000 people with 95% uncertainty intervals () are as follows: Norovirus, 3,188.

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Candida albicans (C. albicans), a major opportunistic pathogenic fungus, is known to cause superficial skin infections. Unfortunately, the misuse of antibiotics has led to the emergence of drug resistance in fungi.

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Article Synopsis
  • - Transportation damage to fresh produce is a significant issue, and existing sensors for monitoring collisions are costly, power-dependent, and not environmentally friendly.
  • - A new self-powered triboelectric sensor made from natural materials has been developed, demonstrating high efficiency and stability, capable of monitoring collisions effectively during transport.
  • - Tests showed that this sensor's output increased with vibration frequency and packing variations, suggesting it could help create smarter food packaging systems to minimize losses in the supply chain.
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The cystic cavity that develops following spinal cord injury is a major obstacle for repairing spinal cord injury (SCI). The injectable self-healing biomaterials treatment is a promising strategy to enhance tissue repair after traumatic spinal cord injury. Herein, a natural extracellular matrix (ECM) biopolymer hyaluronic acid-based hydrogel was developed based on multiple dynamic covalent bonds.

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The industrial Internet of Things (IIoT) environment involves multiple production items, such as robots and automated guided vehicles (AGVs), among others. The practical industrial scenario requires communication of production items while also considering mobile recognition and positioning. Hence the perception approach requires not only combining communications but also realizing the recognition and positioning of multiple communication cells.

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Article Synopsis
  • * Most existing research has concentrated on using terahertz technology for detecting biological materials, with limited studies on its effects on the nervous system.
  • * The article reviews current research on terahertz radiation's biological impacts, discusses challenges in the field, and offers suggestions for future research directions in neuroscience and biomedicine.
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Sulfides possess either high toxicity or play crucial physiological role such as gas transmitter dependent upon dosage, hence the significant for their rapid sensitive and selective concentration determination. Herein, a machine learning enhanced ratiometric fluorescence sensor was engineered for sulfide determination by incorporating the nanometal-organic framework (UiO-66-NH) along with protoporphyrin IX (Ppix). The blue fluorescence at 431 nm originated from the moiety of UiO-66-NH by 365 nm excitation serves as an internal calibration reference signal, while the red fluorescence at 629 nm from the moiety of Ppix serves as the analytical signal, and the intensity is correlated to the amount of sulfides.

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In the current visible light communication (VLC) system, a condenser lens is generally used in the front of receiver to achieve a higher data rate, making an extremely narrow field-of-view for the receiver. With the spread of Industrial Internet of Things (IIoT), the communication between mobile terminals is urgently required. A wide-range detecting method for VLC system in IIoT scenario is asked.

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Epilepsy severely impairs the cognitive behavior of patients. It remains unclear whether epilepsy-induced cognitive impairment is associated with neuronal activities in the medial entorhinal cortex (MEC), a region known for its involvement in spatial cognition. To explore this neural mechanism, we recorded the spikes and local field potentials from MEC neurons in lithium-pilocarpine-induced epileptic rats using self-designed microelectrode arrays.

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Insomnia is a common sleep disorder around the world, which is harmful to people's health, daily life, and work. The paraventricular thalamus (PVT) plays an essential role in the sleep-wake transition. However, high temporal-spatial resolution microdevice technology is lacking for accurate detection and regulation of deep brain nuclei.

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Threatened animals respond with appropriate defensive behaviors to survive. It has been accepted that midbrain periaqueductal gray (PAG) plays an essential role in the circuitry system and organizes defensive behavioral responses. However, the role and correlation of different PAG subregions in the expression of different defensive behaviors remain largely unexplored.

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The electrophysiological activities of head direction (HD) cells under visual and vestibular input dissociation are important to understanding the formation of the sense of direction in animals. In this paper, we fabricated a PtNPs/PEDOT:PSS-modified MEA to detect changes in the discharge of HD cells under dissociated sensory conditions. The electrode shape was customized for the retrosplenial cortex (RSC) and was conducive to the sequential detection of neurons at different depths in vivo when combined with a microdriver.

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Hydrogel adhesives integrating both rapid and strong adhesion to blooding tissues and biocompatibility are highly desired for fast hemostasis. Herein, a flexible hyaluronic acid hydrogel adhesive is fabricated via photocrosslinking of the solution originating from dopamine-conjugated maleic hyaluronic acid (DMHA) in situ. The introduction of acrylate groups with high substitutions into the hydrogel matrix endows the adhesive with rapid gelation and strong tissue adhesion properties through photopolymerization.

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Precise and directional couplings of functional nanomaterials with implantable microelectrode arrays (IMEAs) are critical for the manufacture of sensitive enzyme-based electrochemical neural sensors. However, there is a gap between the microscale of IMEA and conventional bioconjugation techniques for enzyme immobilization, which leads to a series of challenges such as limited sensitivity, signal crosstalk, and high detection voltage. Here, we developed a novel method using carboxylated graphene oxide (cGO) to directionally couple the glutamate oxidase (GluOx) biomolecules onto the neural microelectrode to monitor glutamate concentration and electrophysiology in the cortex and hippocampus of epileptic rats under RuBi-GABA modulation.

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Hypoglycemia state damages the organism, and glucose-excited and glucose-inhibited neurons from the ventral medial hypothalamus can regulate this state. Therefore, it is crucial to understand the functional mechanism between blood glucose and electrophysiology of glucose-excited and glucose-inhibited neurons. To better detect and analyze this mechanism, a PtNPs/PB nanomaterials modified 32-channel microelectrode array with low impedance (21.

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Self-healing natural hydrogels still suffer from some issues such as unfit stiffness, poor healing efficiency, and lack of biocompatibility and hydrolytic stability, although they have been used to treat spinal cord injury (SCI). Herein, we develop the injectable, self-healing hyaluronate hydrogels based on multiple dynamic covalent bonds. The hydrogels exhibit fast gelation and excellent self-healing capability as well as injectability, favoring in situ formation for the hydrogels in target sites and maintaining their structural stability.

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Place cells establish rapid mapping relationships between the external environment and themselves in a new context. However, the mapping relationships of environmental cues to place cells in short-term memory is still completely unknown. In this work, we designed a silicon-based motion microelectrode array (mMEA) and an implantation device to record electrophysiological signals of place cells in CA1, CA3, and DG regions in the hippocampus of ten mice in motion, and investigated the corresponding place fields under distal or local cues in just a few minutes.

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Grid cells with stable hexagonal firing patterns in the medial entorhinal cortex (MEC) carry the vital function of serving as a metric for the surrounding environment. Whether this mechanism processes only spatial information or involves nonspatial information remains elusive. Here, we fabricated an MEC-shaped microelectrode array (MEA) to detect the variation in neural spikes and local field potentials of the MEC when rats forage in a square enclosure with a planar, three-dimensional object and social landmarks in sequence.

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The neural mechanisms of torpor have essential reference significance for medical methods and long-term manned space. Changes in electrophysiology of suprachiasmatic nucleus (SCN) conduce to revealing the neural mechanisms from the torpor to arousal. Due to the lower physiology state during the torpor, it is a challenge to detect neural activities on freely behaving mice.

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The medial amygdala (MA) plays an important role in the innate fear circuit. However, the electrophysiological mechanism of MA for processing innate fear needs to be further explored. In this study, we fabricated microelectrode arrays (MEAs) with detecting sites arranged to match the location and shape of MA in mice and detected the electrophysiology in freely behaving mice under 2-methyl-2-thiazoline (2MT)-induced fear.

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Defense is the basic survival mechanism of animals when facing dangers. Previous studies have shown that the midbrain periaqueduct gray (PAG) was essential for the production of defense responses. However, the correlation between the endogenous neuronal activities of the dorsal PAG (dPAG) and different defense behaviors was still unclear.

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Hyaluronic acid (HA) hydrogel is preferred for biomedicine applications, as it possesses biodegradability, biocompatibility, and cell-regulated capacity as well as high hydration nature similar to the native extracellular matrix. However, HA hydrogel fabricated via a 3D printing technique often faces poor printing properties. In this study, maleiated sodium hyaluronate (MHA) with a high substituted degree of the acrylate group (i.

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