EGFL6 activates the ERK signaling to improve angiogenesis and osteogenesis of BMSCs in patients with steroid-induced osteonecrosis of the femoral head.

Recently, epidermal growth factor-like domain protein 6 (EGFL6) was proposed as a candidate gene for coupling angiogenesis to osteogenesis during bone repair; however, the exact role and underlying mechanism are largely unknown. Here, using immunohistochemical and Western blotting analyses, we found that EGFL6 was downregulated in the femoral head tissue of patients with steroid-induced osteonecrosis of the femoral head (SONFH) compared to patients with traumatic femoral neck fracture (FNF), accompanied by significantly downregulation of osteogenic and angiogenic marker genes. Then, bone marrow mesenchymal stem cells (BMSCs) were isolated from the FNF and the SONFH patients, respectively, and after identification by immunofluorescence staining surface markers, the effect of EGFL6 on their abilities of osteogenic differentiation and angiogenesis was evaluated.

Collaborative semi-global stereo matching.

Efficiency and accuracy of semi-global matching (SGM) make it outperform many stereo matching algorithms and is widely used under challenging occasions. However, SGM only incorporates information along a scanline in each pass and lacks interaction between scanlines, resulting in streak artifacts in the disparity image. We introduce a local edge-aware filtering method to SGM to enhance the interaction of neighboring scanlines, since streak artifacts can be avoided.

Approximate geodesic distance tree filter for cost aggregation.

The computation of the disparity for the pixels in the weak texture area has always been a difficult task in stereo vision. The non-local method based on a minimum spanning tree (MST) provides a solution to construct content-adaptive support regions to perform cost aggregation. However, it always introduces error disparity in slanted surfaces and is sensitive to noise and highly textural regions.

Four-direction global matching with cost volume update for stereovision.

The accuracy and speed of semi-global matching (SGM) make it widely used in many computer vision problems. However, SGM often struggles in dealing with pixels in the homogeneous regions and also suffers from streak artefacts for weak smoothness constraints. Meanwhile, we observe that the global method usually fails in occluded areas.

Photometric invariant stereo matching method.

A robust stereo matching method based on a comprehensive mathematical model for color formation process is proposed to estimate the disparity map of stereo images with noise and photometric variations. The band-pass filter with DoP kernel is firstly used to filter out noise component of the stereo images. Then the log-chromaticity normalization process is applied to eliminate the influence of lightning geometry.