The genomic landscape of short tandem repeats in cattle.

Short tandem repeats (STRs) are abundant and have high mutation rates across cattle genomes; however, comprehensive exploration of cattle STRs is needed. Here, we constructed a comprehensive map of 467 553 polymorphic STRs (pSTRs) constructed from 423 cattle genomes representing 59 breeds worldwide. We observed that pSTRs in coding sequences and 5'UTRs (Untranslated Regions) were under strong selective constraints and exhibited a relatively low level of diversity.

Photoreforming of Plastic Waste to Sustainable Fuels and Chemicals: Waste to Energy.

The extensive accumulation of plastic waste has given rise to severe environmental pollution issues. Contemporary conventional recycling methods, such as incineration and landfilling, contribute significantly to pollutant emissions and carbon footprints, against the principles of sustainable development. Leveraging renewable solar energy to transform plastics into high-value chemicals and green fuels offers a more promising and sustainable approach to managing plastic waste resources.

CaCO-encircled hollow CuS nanovehicles to suppress cervical cancer through enhanced calcium overload-triggered mitochondria damage.

Cervical cancer stands is a formidable malignancy that poses a significant threat to women's health. Calcium overload, a minimally invasive tumor treatment, aims to accumulate an excessive concentration of Ca within mitochondria, triggering apoptosis. Copper sulfide (CuS) represents a photothermal mediator for tumor hyperthermia.

Tailoring Cathode-Electrolyte Interface for High-Power and Stable Lithium-Sulfur Batteries.

Global interest in lithium-sulfur batteries as one of the most promising energy storage technologies has been sparked by their low sulfur cathode cost, high gravimetric, volumetric energy densities, abundant resources, and environmental friendliness. However, their practical application is significantly impeded by several serious issues that arise at the cathode-electrolyte interface, such as interface structure degradation including the uneven deposition of LiS, unstable cathode-electrolyte interphase (CEI) layer and intermediate polysulfide shuttle effect. Thus, an optimized cathode-electrolyte interface along with optimized electrodes is required for overall improvement.

(Gesneriaceae), a New Species From Southwestern Guangxi, China.

The genus is renowned for its remarkably diverse floral morphology, exhibiting a high level of disparity compared to most genera within Gesneriaceae. In this study, we present a detailed description and illustration of T. Ding & B.

Effect of the diet level of whole-plant corn silage on the colonic microflora of Hezuo pigs.

Background: Whole-plant corn silage (WPCS) is an important roughage source for livestock, and have critical influences on rumen or intestinal microbiota, thus affecting the growth performance and feed efficiency. Our previous studies showed that adding WPCS to the diet of Hezuo pigs could promote the growth and fiber digestibility. While the aim of this study is to understand the effect of dietary WPCS on the colonic microflora in Hezuo pigs, which is essential for improving the roughage exploitation of pigs.

Sophoricoside reduces inflammation in type II collagen-induced arthritis by downregulating NLRP3 signaling.

Immune responses, especially NLRP3 signaling in macrophages, play critical roles in rheumatoid arthritis (RA), an autoimmune and inflammatory disease. In this study, we aimed to identify novel therapies for RA. We focused on sophoricoside (SOP), an isoflavone glycoside isolated from .

Near-infrared AIE chemiluminescence probe for monitoring and evaluating singlet oxygen in vivo.

The incorporation a "singlet oxygen (O) battery" into photodynamic therapy (PDT) could overcome the deficiency of tumor hypoxia in PDT and enhance its effect. However, real-time monitoring the O release efficiency of the O battery still presents a significant challenge in vivo. To address this issue, we have developed a bright aggregation-induced emission (AIE) chemiluminescence (CL) probe (DTLum), which conjugates a luminol unit with a donor-acceptor structured diketopyrrolopyrrole fluorophore, for the specific detection of O.

Facile synthesis of carbon-coated CoS micro/nano-spheres as high-performance anode materials for sodium-ion batteries.

carbon-coated CoS micro/nano-spheres were successfully prepared by sulfuric calcination using the solvothermal method with glycerol as the carbon source without introducing extraneous carbon. This method prevents carbon agglomeration and avoids the cumbersome steps of the current technology. The composite demonstrates excellent sodium storage capacity as an anode material for sodium-ion batteries.

Eight-wavelength-switchable single-frequency fiber laser with scattering-enhanced fiber-based wavelength self-adaptive linewidth compression.

We demonstrate an eight-wavelength-switchable single-frequency (SF) ultra-narrow linewidth erbium-doped fiber laser (EDFL). A switchable polarization-dependent eight-channel filter (S-PDECF), fabricated using femtosecond laser direct-writing technology, determines the eight wavelengths of the laser output, with four channels concentrated near 1530 nm and the other four near 1550 nm. A dual-coupler ring-based compound-cavity filter is utilized to achieve single-longitudinal-mode selection for the EDFL.

Higher HEI-2015 score is associated with reduced risk of fecal incontinence: insights from a large cross-sectional study.

Objective: Diet habit plays a vital role in fecal incontinence (FI) progression. However, it remains unknown whether dietary quality is related to FI. Our study sought to explore the relationship between healthy eating index-2015 (HEI-2015) score and FI among US adults.

Computer tomography-based radiomics combined with machine learning for predicting the time since onset of epidural hematoma.

Estimation of the age of epidural hematoma (EDH) is a challenge in clinical forensic medicine, and this issue has yet to be conclusively resolved. The advantages of objectivity and non-invasiveness make computing tomography (CT) imaging an potential diagnostic method for EDH in living individuals. Recently, radiomics, the extraction hidden information from medical images, has emerged as a promising method for constructing predictive models.

Global Environmental and Toxicological Data of Emerging Plasticizers: Current Knowledge, Regrettable Substitution Dilemma, Green Solution and Future Perspectives.

The global plasticizer market is projected to increase from $17 billion in 2022 to $22.5 billion in 2027. Various emerging/alternative plasticizers entered the market following the ban on several phthalate plasticizers because of their harmful effects.

Arbuscular mycorrhizal fungi mediate soil N dynamics, mitigating NO emissions and N-leaching while promoting crop N uptake in green manure systems.

Arbuscular mycorrhizal fungi (AMF), as symbionts of the plant root system, play a pivotal ecological role in soil nutrient dynamics. However, the mechanisms by which AMF mediates nitrogen (N) transformation at the soil-crop interface, particularly under green manure management, remain insufficiently understood. This study investigates these mechanisms through a long-term field experiment, employing four green manure management practices during the flowering stage of common vetch: tillage with total green manure incorporation (TG), no-tillage with total green manure mulching (NTG), aboveground biomass removal with root incorporation (T), and aboveground biomass removal with no-tillage (NT), alongside a conventional tillage control without green manure (CT).

Flexible and reconfigurable integrated optical filter based on tunable optical coupler cascaded with coupled resonator optical waveguide.

Reconfigurable optical filter can satisfy diverse filtering requirements in different application scenarios and shorten development cycle. However, it is still challenging to achieve multi-functional filtering richness with high performance. Here, based on a tunable optical coupler cascaded with a coupled resonator optical waveguide (CROW), a highly flexible and reconfigurable integrated optical filter is proposed and demonstrated on the low-loss silicon nitride platform.

Activating Oxygen via the 3-Electron Pathway to Hydroxyl Radical by La-O Single-atom on WO for Water Purification.

Shifting photocatalytic oxygen activation towards 3-electron (e) pathway to hydroxyl radicals, instead of the normal 1 e to superoxide radicals, becomes increasingly important for pollution degradation since hydroxyl radicals possess a high oxidation potential (2.80 V). Here, we demonstrate a selective oxygen activation to hydroxyl radicals via 3 e pathway using single atomically dispersed La based on WO fabricated with oxygen vacancies to weaken La-O coordination strength (denoted as LaO-WO).

NcPTP2, a polar tube protein, interacts with spore wall protein in the parasitic microsporidian Nosema ceranae.

Background: Microsporidia is an obligate intracellular eukaryote, which is capable of parasitizing vertebrates and invertebrates. Nosema ceranae, which can infect both Apis mellifera and Apis cerana, poses a serious threat and causes heavy losses to the worldwide apiculture. During infection, polar tube, a highly specialized invasion structure, ejected from the spore to deliver the sporoplasm into host cells to cause infection.

Interfacial Proton Precompensation: Suppressing Deprotonation-Driven Lattice Collapse for Enhanced Efficiency and Stability in Perovskite Solar Cells.

The chemical property of the buried interface plays a crucial role in improving the performance and stability of perovskite solar cells (PSCs). The SnO/perovskite interface prepared from SnO alkaline hydrogel with high proton affinity triggers directional migration and irreversible reactions of protons, exacerbating the disintegration of perovskite crystal. In this study, we proposed proton precompensation strategy to suppress the deprotonation effect of the buried interface and improve the durability of the devices.

Mitigating Mechanical Stress by the Hierarchical Crystalline Domain for High-Energy P2/O3 Biphasic Cathode Materials.

Sodium-ion batteries (SIBs) have captured widespread attention for grid-scale energy storage owing to the wide distribution and low cost of sodium resources. Delivery of high energy density with stable retention remains a challenge in developing cathode candidates for rechargeable SIBs. Inspired by the concept of "cationic potential", here, we present a hierarchical crystalline domain in hexagonal particles with target chemical composition (NaLiMgNiFeMnTiO) from the inner bulk O3 phase (71.

Gender-Specific DNA Methylation Profiles Associated with Adult Weight in Hezuo Pigs.

The Hezuo pig, an important native Tibetan breed in China, exhibits differences in adult body weight, with females typically heavier than males. The underlying mechanisms for this disparity remain unclear. DNA methylation changes are known to influence animal growth and development and regulate Hezuo pig growth by altering gene expression related to these processes, thus differentially affecting adult body weight between genders.

Large-scale dependent multiple testing via higher-order hidden Markov models.

Taking into account the local dependence structure in large-scale multiple testing is expected to improve both the efficiency of the testing procedure and the interpretability of scientific findings. The hidden Markov model (HMM), as an effective model to describe the sequential dependence, has been successfully applied to large-scale multiple testing with local correlations. However, in many applications, the first-order Markov chain is not flexible enough to capture the complexity of local correlations.