The efficient triplet states formation of Se-modified PDI dimers and tetramers in solvents.

The triplet excited states of molecules play an important role in photophysical processes, which has attracted great research interest. Perylene diimide (PDI) is a widely studied material closely associated with the generation of triplet states, and it is highly anticipated to become an electron acceptor material for improving photovoltaic conversion efficiency. In this work, we prepared dimers and tetramers composed of selenium-modified PDI-C5 ('-bis(6-undecyl) perylene-3,4,9,10-bis(dicarboximide)) units.

Predictive value of preoperative routine examination for the prognosis of patients with pT2N0M0 or pT3N0M0 colorectal cancer.

Background: In recent years, the incidence of colorectal cancer (CRC) has been increasing. With the popularization of endoscopic technology, a number of early CRC has been diagnosed. However, despite current treatment methods, some patients with early CRC still experience postoperative recurrence and metastasis.

Simulation Study of Coal Seam Gas Extraction Characteristics Based on Coal Permeability Evolution Model under Thermal Effect.

The permeability evolution law of high temperature and high stress coal seam is determined by the influence of multiphase coexistence and multifield coupling. In an environment greatly affected by disturbance and high temperature, the coal permeability model under the coupling of thermal and mechanical creep is not only a vital framework from which to examine gas migration law in multiphase and multifield coal seams but also an important theoretical foundation for gas control in coal seams. The influence of high-temperature environment on creep deformation and permeability is analyzed by several creep seepage tests under different temperature conditions.

miR-214-5p/C1QTNF1 axis enhances PCV2 replication through promoting autophagy by targeting AKT/mTOR signaling pathway.

Porcine circovirus type 2 (PCV2) is the causative agent of PCV2-associated disease, which causes a relevant economic impact on the global swine industry. Accumulating data have indicated host microRNAs play essential roles in numerous virus replication of pigs, while their roles in PCV2 replication remain unclear. Herein, we demonstrated that PCV2 infection downregulated the expression of miR-214-5p in PK15 cells, and miR-214-5p promoted PCV2 replication.

COVID-19 in children: epidemic issues and candidate vaccines.

A large-scale vaccination of coronavirus disease-19 (COVID-19) in adults has been conducted for nearly a year, and there is a growing recognition that immunization for children is also essential. It has been months since emergency use of pediatric COVID-19 vaccine was approved, we reviewed the prevalence and transmission of COVID-19 in children. The prevalence of COVID-19 in children is reduced due to vaccination even in a Delta prevalent period, so an increase in the vaccination rate is needed in children.

Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Mechanisms in Porcine Intestinal Epithelial Cells under Zearalenone Stress.

Zearalenone (ZEA) is a mycotoxin that frequently occurs in agricultural crops and related products and seriously threatens both animal feed and human food safety. To identify key metabolites and regulators involved in ZEA toxicological processes, we performed metabolomic and transcriptomic analyses of porcine IPEC-J2 intestinal epithelial cells upon ZEA exposure using liquid chromatography-mass spectrometry (LC-MS)/MS and RNA-seq techniques. A total of 325 differential metabolites and 5646 differentially expressed genes were detected.

Effects of HSP27 gene expression on the resistance to Escherichia coli infection in piglets.

Heat shock protein 27 (HSP27) plays an important role in protecting cells from various stress factors. This study aimed to investigate the function of HSP27 gene and its regulatory mechanism as infected by Escherichia coli (E. coli) at the tissue and cellular levels.

Effect of Pore Structure on Thermal Conductivity and Mechanical Properties of Autoclaved Aerated Concrete.

With the premise of investigating mechanical properties, the thermal conductivity of autoclaved aerated concrete (AAC) is a key index of self-insulation block walls for building energy conservation. This study focused on the effect of pore structures on the mechanical performance and thermal conductivity of AAC with the comparison of AAC base materials. Different kinds of AAC and their base materials were prepared and experimentally investigated.

Effects of Adjuvant Therapy Compliance and Anastomotic Leakage on the Oncologic Outcomes of Patients With Rectal Cancer After Curative Resection.

Background: Anastomotic leakage might be directly or indirectly related to the prognosis of patients with rectal cancer.

Objective: This study aimed to investigate whether anastomotic leakage affects the oncologic outcomes in patients with rectal cancer.

Design: This was a retrospective analysis of prospectively collected data.

Phyllodes tumor of the breast with nipple discharge: A case report.

Rationale: Phyllodes tumors (PTs) of the breast are rare biphasic fibroepithelial neoplasms which usually present with unilateral palpable breast lumps. Here we reported a case of borderline PTs with multifocal intraductal lesions whose primary clinical manifestation was nipple discharge.

Patient Concerns: A rare case of PT with nipple discharge in a 26-year-old young lady accepted a wide local excision on her left breast, and the pathological examination turned out to be a malignant phyllodes tumor.

Mercury removal from coal combustion flue gas by modified fly ash.

Fly ash is a potential alternative to activated carbon for mercury adsorption. The effects of physicochemical properties on the mercury adsorption performance of three fly ash samples were investigated. X-ray fluorescence spectroscopy, X-ray photoelectron spectroscopy, and other methods were used to characterize the samples.