Publications by authors named "Pengfei He"

Background And Aims: Diabetic patients are highly susceptible to cardiovascular and renal diseases. As a newly updated comprehensive index for assessing cardiovascular health (CVH), Life's essential 8 (LE8) has the potential to serve as a practical tool for evaluating the risk of diabetic kidney disease (DKD). We are committed to exploring the relationship between LE8 and its subscales with DKD in diabetic patients, aiming to provide preliminary evidence for the formulation of clinical strategies.

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Backgrounds: It has been regarded as an essential treatment option for diabetic nephropathy (DN) in Traditional Chinese medicine. Previous studies have demonstrated the anti-DN efficacy of Schisandra chinensis Fruit Mixture (SM); however, a comprehensive chemical fingerprint is still uncertain, and its mechanism of action, especially the potential therapeutic targets of anti-DN, needs to be further elucidated.

Objective: Potential mechanisms of SM action on DN were explored through network pharmacology and experimental validation.

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This study aimed to detect the causal effect of ulcerative colitis (UC) on heart failure. A bidirectional two-sample Mendelian randomization (MR) analysis was performed. The causal impact of UC on heart failure was determined via MR by performing a genome-wide association study in which 4 UCs descending from European ancestors were set as individual exposures.

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To investigate the influence of early dysphagia on quality of life in patients with partial laryngectomy, and to investigate the application value of Flexible Endoscopic Evaluation of Swallowing (FEES). This study included 30 inpatients who underwent partial laryngectomy due to laryngeal cancer. In the early postoperative period, a comprehensive assessment was conducted on each patient, encompassing Videofluoroscopic Swallowing Study (VFSS), Flexible Endoscopic Evaluation of Swallowing (FEES), and MD Anderson Dysphagia Inventory (MDADI).

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The ultrasensitive piezoelectric sensors with the capability of sound recognition have attracted extensive attention due to their unique characteristics. However, the fabrication of acoustic sensors with favorable flexibility and sensitivity via simple and controllable methods remains a significant challenge. Herein, an ultrasensitive and adaptive acoustic sensor based on piezoelectric polyimide (PI) composite foams containing fluorine groups is developed.

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Background: The Oxidative Balance Score (OBS) quantifies the overall oxidative stress burden, with higher scores indicating greater antioxidant (relative to prooxidant) activity. This study aimed to examine the association between peripheral arterial disease (PAD) and OBS.

Methods And Materials: Data from the National Health and Nutrition Examination Survey (NHANES, 1999-2004) were analyzed for participants with ankle-brachial index (ABI) measurements.

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Objective: The C-reactive protein/Lymphocyte Ratio (CLR) is a novel biomarker whose role in the development of chronic kidney disease (CKD) is not well understood. This study aimed to investigate the correlation between CLR and the prevalence of CKD.

Methods: This cross-sectional study included participants from the US National Health and Nutrition Examination Survey conducted between 1999 and 2010.

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Background: The oxidative balance score (OBS) is a comprehensive concept that includes 16 dietary components and four lifestyle factors to assess an individual's exposure to pro-oxidants and antioxidants. This study aims to explore the relationship between OBS and the risk of chronic kidney disease (CKD).

Methods: This cross-sectional study included nationally representative National Health and Nutrition Examination Survey (NHANES) participants aged 18 and above from 2005 to 2018.

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Banana crop ranks among the most crucial fruit and food crops in tropical and subtropical areas. Despite advancements in production technology, diseases such as cordana leaf spot, caused by , remain a significant challenge, reducing productivity and quality. Traditional chemical controls are becoming less effective due to the development of resistance in target pathogens, which pose significant environmental and health concerns.

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Background: Tomato-spotted wilt virus (TSWV) from the Tospovirus genus affects over 1000 plant species, including key crops, and traditional control methods often prove inadequate. This study investigates the effectiveness of Bacillus amyloliquefaciens and Bacillus subtilis in reducing TSWV infection, enhancing plant growth, and strengthening defense in Nicotiana benthamiana. The aim is to assess Bacillus as a sustainable biocontrol alternative, offering an eco-friendly solution for managing TSWV disease in agriculture.

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Recently, due to the widespread use of the acetolactate synthase (ALS)-inhibiting herbicide penoxsulam in paddy fields in China, (L.) P. Beauv.

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Maize (Zea mays. L) is cultivated globally as a staple food crop, animal feed, and biofuel. However, persistent diseases in maize have led significant yield losses and a decline in grain quality (Yang et al.

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Metabolites of plant and microbial origin have a great influence on plant-microbe interactions. Members from Bacillus subtilis are known to produce a plethora of metabolites that shape plant responses towards biotic and abiotic stresses. Similarly, endophyte B.

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Article Synopsis
  • Far infrared radiation (FIR) between 4-14 μm can benefit human health by improving blood flow, leading to the development of health-promoting textiles using FIR-emitting additives in polymer fabrics.
  • The study focused on biochar from candlenuts combined with activated carbon in polypropylene films, finding that its inclusion increased FIR emissivity and enhanced UV/NIR blocking capabilities.
  • Biochar significantly improved temperature retention and tensile strength of the fibers, suggesting its potential for use in warming clothing and longer-lasting materials compared to other common additives.
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Microbiomes are sustained through infinite yet mutually interacting microbial communities, with bacteria and fungi serving as the major constituents. In recent times, microbial interventions have become popular for microbiome manipulation to achieve sustainable goals. Whether and how the introduced biocontrol agent drives fungal microbial assemblages (mycobiome) and the role of interkingdom signaling in shaping the microbiome structure and function remain poorly understood.

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Introduction: The role of immune cells in the pathogenesis and advancement of diabetic nephropathy (DN) is crucial. The objective of this study was to identify immune-cell-related biomarkers that could potentially aid in the diagnosis and management of DN.

Methods: The GSE96804 dataset was obtained from the Gene Expression Omnibus (GEO) database.

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Article Synopsis
  • The murine model plays a key role in studying gut microbes and their interactions with hosts and diseases, but the effects of genetic variations on the microbiome in disease contexts, especially with the pathogen Klebsiella pneumoniae (Kp), are not fully understood.
  • The study utilized different mouse models to analyze the microbiome's response during Kp infection, revealing significant differences in microbial composition between wild-type and mutant strains, which could affect disease progression and pathogen virulence.
  • These findings emphasize the complexity of microbiome-immune interactions and suggest new avenues for therapeutic strategies targeting gut microbiota in infections.
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Antibiotics play an essential role in the aquaculture industry, but their overuse and weak degradability inevitably lead to light to severe residues in natural and aquaculture environments. Most studies were interested in the occurrence, distribution, and ecological risks of a limited number of antibiotics in natural environments (rivers, lakes, and coastal regions) with a minor focus on antibiotic presence in either water, sediments, or organisms in aquaculture environments located in specific regions. In this study, we conducted a comprehensive investigation into the occurrence and distribution of up to 32 antibiotics [including 15 quinolones (QNs) and 17 sulfonamides (SAs)] in organisms and their corresponding environmental matrices from 26 freshwater aquaculture ponds in Northeast Zhejiang, China.

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Article Synopsis
  • A polysaccharide named CZS-0-1 was extracted from the marine green algae Codium fragile using specific chromatography techniques, revealing it to be a sulfated galactoarabinan with an arabinose, galactose, and glucose ratio of 9:2:1 and 21% sulfate content.
  • Structural analysis showed that the backbone consisted mainly of (1 → 3)-β-L-Arap, with branches and sulfate modifications enhancing its complex configuration.
  • CZS-0-1 displayed significant anticoagulant effects similar to heparin by inhibiting specific blood factors (FIIa and FXa), with its activity closely linked to its molecular weight, suggesting potential as a source for bioactive polys
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Article Synopsis
  • The study aimed to explore the relationship between the oxidative balance score (OBS), which includes various oxidative stressors, and the risk of diabetic kidney disease (DKD), low estimated glomerular filtration rate (eGFR), and albuminuria in diabetes patients.
  • Using data from the National Health and Nutrition Examination Survey from 2003-2018, the researchers analyzed 5,389 diabetic participants, finding a negative association between high OBS and the risk of DKD and related conditions.
  • The results suggested that individuals in the highest quartile of OBS had significantly reduced risks of DKD, low-eGFR, and albuminuria, highlighting the potential benefits of an antioxidant-rich diet and lifestyle for those with diabetes.
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Dodder ( spp.) is a dangerous parasitic plant that causes serious damage to crop production and is challenging to eliminate. Herbicide application is a common strategy to control dodder in the field, but it is costly, ineffective, and further results in hazardous outcomes.

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Prolonged sitting can easily result in pressure injury (PI) for certain people who have had strokes or spinal cord injuries. There are not many methods available for tracking contact surface pressure and shear force to evaluate the PI risk. Here, we propose a smart cushion that uses two-dimensional force sensors (2D-FSs) to measure the pressure and shear force in the buttocks.

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Background: Exercise therapy can effectively manage chronic kidney disease (CKD) risk factors and improve renal function and physical fitness, but the challenge lies in choosing the right exercise type tailored to patients' condition.

Methods: An electronic search of databases including PubMed, The Cochrane Library, EMBASE, Web of Science, VIP, WanFang, and CNKI was performed. The random effects model was used.

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The pod and seed counts are important yield-related traits in soybean. High-precision soybean breeders face the major challenge of accurately phenotyping the number of pods and seeds in a high-throughput manner. Recent advances in artificial intelligence, especially deep learning (DL) models, have provided new avenues for high-throughput phenotyping of crop traits with increased precision.

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The abuse and irrational use of tetracyclines (TCs) in human medicine and animal husbandry has become a serious concern, affecting the ecological environment and human health. The aim of this study was to develop a sensitive and selective method using fully automatic solid-phase extraction coupled with ultra-performance liquid chromatography-tandem mass spectrometry for the determination of twelve TCs in water. Four isotope-labeled internal standards for TCs were used to correct matrix effects.

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