Publications by authors named "Pengfei Chai"

This study aimed to analyze peripheral blood lymphocyte subsets in lupus nephritis (LN) patients and use machine learning (ML) methods to establish an effective algorithm for predicting co-infection in LN. This study included 111 non-infected LN patients, 72 infected LN patients, and 206 healthy controls (HCs). Patient information, infection characteristics, medication, and laboratory indexes were recorded.

View Article and Find Full Text PDF
Article Synopsis
  • This study looked at how drinking water with different metals affects people's chances of getting depression and anxiety.
  • It involved over 24,000 people and found that some metals, like manganese, can lower depression risk, while others, like copper and cadmium, can increase it.
  • The research also showed that what people eat can change how these metals impact their mental health, with more effects noticed in older and less wealthy people.
View Article and Find Full Text PDF

Environmental factors, such as drinking water and diets, play an important role in the development of inflammatory bowel disease (IBD). This study aimed to investigate the associations of metal elements and disinfectants in drinking water with the risk of inflammatory bowel disease (IBD) and to assess whether diet influences these associations. We conducted a prospective cohort study including 22,824 participants free from IBD from the Yinzhou cohort study in the 2016-2022 period with an average follow-up of 5.

View Article and Find Full Text PDF

Fine particulate matter (PM) is a mixture of multiple components, which is associated with several chronic diseases, including respiratory and cardiovascular diseases. We evaluated the association between daily PM and PM exposure and hospital visits for respiratory diseases. Hospital visits for respiratory diseases were collected from Yinzhou Health Information System database.

View Article and Find Full Text PDF
Article Synopsis
  • A study in Ningbo, China, examined the short-term health impacts of fine and coarse particulate matter (PM) on cardiovascular hospital visits, addressing inconsistencies found in previous research.
  • The results indicated a significant association between fine particulate matter (PM2.5) and increased cardiovascular hospital visits, particularly stronger in the cold season and among older adults (≥ 75 years).
  • However, no independent effect of coarse particulate matter (PM10) was found after controlling for fine particulate matter, highlighting the need for further research to confirm these outcomes.
View Article and Find Full Text PDF

Acute upper and lower respiratory infections are main causes of mortality and morbidity in children. Air pollution has been recognized as an important contributor to development and exacerbation of respiratory infections. However, few studies are available in China.

View Article and Find Full Text PDF

Unlabelled: Recently, air pollution has attracted a substantial amount of attention in China, which can be influenced by a variety of factors, but the association between air pollution and human activity is not quite clear. Based on real-time online data (January 1, 2014, to December 31, 2014) of air pollution and meteorology reported by official sites, and demographic, economic, and environmental reform data in a statistical yearbook, the influences of meteorological factors (temperature, relative humidity, precipitation intensity, and wind force) and human activities on PM pollution were explored. After correlation analysis, logistic regression analysis, and a nonparametric test, weak negative correlations between temperature and PM pollution were found.

View Article and Find Full Text PDF

A recent multi-center case-control study identified several single nucleotide polymorphisms (SNPs) within the cytokine-inducible SRC homology 2 domain (CISH) gene that are associated with susceptibility to tuberculosis (TB) in both African and Asian populations. To acquire a more robust and well-powered estimate of the putative influence of these SNPs on TB susceptibility, we conducted a well-designed case-control study in the Chinese Han population. We genotyped 3 previously identified SNPs within CISH in 600 patients with pulmonary TB and 618 healthy controls, and we calculated the pooled P-values and ORs of several studies that have also been conducted in the Chinese populations.

View Article and Find Full Text PDF

Genome-wide association studies (GWAS) have identified rs4331426 and rs2057178 as being associated with tuberculosis (TB) in African populations. Both are common single nucleotide polymorphisms (SNPs) in Africans, but they are much rarer in Eurasian populations. In order to corroborate these results, we carried out a case-control study in the Chinese population; these 2 SNPs were genotyped in 600 pulmonary TB patients and 618 healthy controls.

View Article and Find Full Text PDF