Publications by authors named "Pengbo Ge"

Objectives: Pregnancy outcomes of different ovarian stimulation protocols for in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) in patients with adenomyosis are not explicit. This meta-analysis aimed to systematically evaluate the effects of different IVF/ICSI protocols on pregnancy outcomes.

Design: Meta-analysis.

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Gastric cancer (GC) is one of the most common malignancies worldwide. TGF-β1 induces the epithelial-mesenchymal transition (EMT) in GC, mainly through Smad-dependent pathways. Nevertheless, few studies have focused on the activation of non-canonical transduction pathways.

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Article Synopsis
  • - Increasing evidence shows that flotillins, proteins associated with tumor progression, are overexpressed in various cancers, but their role in prognosis remains debated.
  • - A meta-analysis of 27 studies involving 4,803 cancer patients revealed that higher levels of flotillins are linked to significantly poorer overall survival (OS) and disease-free survival (DFS) across different tumor types.
  • - Despite consistent findings, the research indicates that more clinical studies are needed to further establish flotillins as reliable biomarkers for poor cancer prognosis, especially since their prognostic value seems unaffected by factors like tumor type or location.
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