MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis.

Background: MiRNAs are closely related to tumor radiosensitivity. MiR-378a-5p level is down-regulated in colorectal cancer (CRC). Therefore, this study intends to explore the role of miR-378a-5p in CRC, especially radiosensitivity.