Experiment and Computational Study on Pd-Catalyzed Methoxyiminoacyl-Directed γ-Alkoxylation of Alkylamides.

The direct alkoxylation of amides has been accomplished via methoxyiminoacyl (MIA)-mediated Pd-catalyzed C-H functionalization. A diverse array of alkylamide substrates is amenable to this protocol, providing γ-C(sp)-alkoxylation of alkylamide derivatives with good to high efficiency. Two aspects of the research were completed to explore the reaction mechanism.

A new species of Westwood, 1842 from Yunnan, China (Hemiptera, Cicadidae, Cicadinae).

Background: The tribe Polyneurini Amyot & Audinet-Serville, 1843 (Hemiptera: Cicadidae: Cicadinae) is a small tribe which includes four genera and 18 species, distributing in eastern Palaearctic and Oriental Regions. Most of them, four genera and 16 species, are known from China.

New Information: A remarkable new species of cicada, (Hemiptera, Cicadidae, Cicadinae), is described and illustrated from Yunnan, southwest China.

Metallophilic Interaction-Mediated Hierarchical Assembly and Temporal-Controlled Dynamic Chirality Inversion of Metal-Organic Supramolecular Polymers.

The study of dynamic supramolecular chirality inversion (SMCI) not only helps to deepen the understanding of chiral transfer and amplification in both living organizations and artificially chemical self-assembly systems but also is useful for the development of smart chiral nanomaterials. However, it is still challenging to achieve the dynamic SMCI of the self-aggregation of metal-organic supramolecular polymers with great potential in asymmetric synthesis, chiroptical switches, and circular polarized luminescence. Here, we successfully developed a hierarchical coassembly system based on the PAzPCC and various metal ions with effective chirality transfer and temporal-controlled SMCI.

Copper/silver -mediated three-component bicyclization for accessing indeno[1,2-]azepine-3,6-diones.

A new copper/silver-co-mediated three-component bicyclization of benzene-linked 1,6-enynes with ICF2CO2Et with TMSN3 was reported, and used to produce a wide range of hitherto unreported difluorinated tetrahydroindeno[1,2-c]azepine-3,6-diones with moderate to good yields. The mechanistic pathway consists of radical-induced 1,6-addition-cyclization, oxidative addition, reductive elimination, nitrene insertion and N-O cleavage, resulting in continuous multiple bond-forming events including C-C and C-N bonds to build up a 6/5/7 tricyclic framework.

Au(I)-Catalyzed Domino Cyclization of 1,6-Diynes Incorporated with Indole.

We disclose herein a Au(I)-catalyzed domino cyclization of 1,6-diynes incorporated with indole. This protocol enabled the diastereoselective buildup of indole-fused azabicyclo[3.3.

A water stable Eu(III)-organic framework as a recyclable multi-responsive luminescent sensor for efficient detection of -aminophenol in simulated urine, and Mn and Cr anions in aqueous solutions.

A novel 3D Eu(iii) metal-organic framework (Eu-MOF-1) formulated as [Eu(L)(H2O)(DMA)] (L = 2-(2-nitro-4-carboxylphenyl)terephthalic acid) has been successfully synthesized under solvothermal conditions and characterized by structural analyses. Eu-MOF-1 displays a new 3D framework containing EuIII ions, ligand L, and coordinated DMA molecules and water molecules. The fluorescence investigations indicate that Eu-MOF-1 emits bright red luminescence, and shows relatively high water stability and outstanding chemical stability under a relatively wide range of pH conditions.

Single-Cell Sequencing and Organoids: A Powerful Combination for Modelling Organ Development and Diseases.

The development and function of a particular organ and the pathogenesis of various diseases remain intimately linked to the features of each cell type in the organ. Conventional messenger RNA- or protein-based methodologies often fail to elucidate the contribution of rare cell types, including some subpopulations of stem cells, short-lived progenitors and circulating tumour cells, thus hampering their applications in studies regarding organ development and diseases. The scRNA-seq technique represents a new approach for determining gene expression variability at the single-cell level.

MIA-Directed 2-Pyridione-Enabled Selective -C-H Arylation of Phenylalanine: A Mechanistic Study.

The 2-methoxyiminoacyl-mediated arylation of substituted phenylalanines has been examined. Selective monoarylation at the position was achieved using pyridone ligands which decelerate the arylation process. Density functional theory (DFT) study of a continuous C-H arylation process that included the first and second arylation stage was performed.

Water-stable Cd(ii)/Zn(ii) coordination polymers as recyclable luminescent sensors for detecting hippuric acid in simulated urine for indexing toluene exposure with high selectivity, sensitivity and fast response.

Three novel Cd(ii)/Zn(ii) coordination polymers (CPs), namely [Cd(L)(BPDC)HO]·0.5HO (1), [Zn(L)(BPDC)]·2HO (2) and [Cd(L)(BTC)HO]·3HO (3) (L = 4-(tetrazol-5-yl)phenyl-4,2':6',4''-terpyridine, HBPDC = 4,4'-biphenyldicarboxylic acid, and HBTC = 1,3,5-benzenetricarboxylic acid), have been successfully synthesized and characterized. CP 1 and CP 2 display new two-dimensional double-layered honeycomb frameworks containing uncoordinated nitrogen atoms from pyridine and tetrazole rings, which can easily form hydrogen bonds with various analytes.

A review of the genus Trachystolodes Breuning, 1943 (Coleoptera: Cerambycidae: Lamiinae: Lamiini).

A taxonomic review of the genus Trachystolodes Breuning is presented. A new species, Trachystolodes huangjianbini sp. nov.

[Regional Evolution and Control Factors of Karst Groundwater in Liulin Spring Catchment].

The Liulin Spring is one of the ten most famous karst springs in the Shanxi province. The abundant karst groundwater resources support the economic and social development in the Luliang Prefecture. Therefore, the study of evolution and control factors of karst groundwater is of great significance to the sustainable utilization of water resources in the watershed.

[Migration and Transformation of Dissolved Organic Matter in Karst Water Systems and an Analysis of Their Influencing Factors].

Fluorescent substances are used as good tracers in dissolved organic matter (DOM) to identify the source of DOM and its geochemical behavior in a hydrological system. However, there are few studies on the karst aquifer system. Many parameters in karst systems affect the DOM spectral information.

Metal-Free Aerobic Oxidative Cyanation of Tertiary Amines: Azobis(isobutyronitrile) (AIBN) as a Sole Cyanide Source.

An aerobic oxidative cyanation for the synthesis of α-aminonitriles was reported. The formation of C(sp)-CN bonds was achieved under a metal-free condition by utilizing azobis(isobutyronitrile) as a sole organic cyanide source with the combination of pivalic acid and sodium acetate as additives.

Impact of sulfuric and nitric acids on carbonate dissolution, and the associated deficit of CO uptake in the upper-middle reaches of the Wujiang River, China.

Carbonate weathering and the CO consumption in karstic area are extensive affected by anthropogenic activities, especially sulfuric and nitric acids usage in the upper-middle reaches of Wujiang River, China. The carbonic acid would be substituted by protons from sulfuric and nitric acids which can be reduce CO absorption. Therefore, The goal of this study was to highlight the impacts of sulfuric and nitric acids on carbonate dissolution and the associated deficit of CO uptaking during carbonate weathering.

[Major Ionic Features and Their Controlling Factors in the Upper-Middle Reaches of Wujiang River].

The Wujing River, the largest river in Guizhou Province, is one of the most important water resources for social and economical development. Recently, with the fast population proliferation and rapid economic growth, the drainage basin is intensively interfered by anthropogenic activities. The hydrochemistry of surface water was analyzed from the upper-middle reaches of Wujiang River for investigating the hydrochemical characteristics and their main influencing factors.

Protective effect of Danggui (Radix Angelicae Sinensis) on angiotensin II-induced apoptosis in H9c2 cardiomyoblast cells.

Background: Danggui (Radix Angelicae Sinensis) is an herb often used in Traditional Chinese medicine. It is used to promote blood flow and has been used in the treatment of myocardial ischemia-reperfusion injury in animal models. Angiotensin II (Ang II) has been shown to play important roles in mediating cardiovascular diseases, and may cause cardiac hypertrophy and apoptosis.

[Transported fluxes of the riverine carbon and seasonal variation in Pearl River basin].

The riverine carbon flux is a critical component of global carbon cycle. Riverine water samples were collected from eleven hydrometric stations in the main stream of Pearl River and its tributaries during April and July, 2012. The samples were analyzed for the space and seasonal distribution characteristics of the riverine suspended substance and carbon compositions.