Publications by authors named "Peng-fei Cai"
The daily life of people in the intelligent age is inseparable from electronic device, and a number of bacteria on touch screens are increasingly threatening the health of users. Herein, a photocatalytic TiO/Ag thin film was synthesized on a glass by atomic layer deposition and subsequent in situ reduction. Ultraviolet-visible (UV-Vis) spectra showed that this film can harvest the simulated solar light more efficiently than that of pristine TiO.
View Article and Find Full Text PDF[Methodological Evaluation of Microarray in the Detection of α-Thalassemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2021
Article Synopsis
- The study aimed to clinically evaluate the effectiveness of DNA microarray for detecting thalassemia genes using peripheral blood samples from 166 subjects.
- Microarray chip method demonstrated high accuracy with 100% specificity and positive predictive values, significantly outperforming traditional Gap-PCR and PCR-reverse dot blot hybridization methods in terms of detection rates.
- Findings conclude that the microarray chip method is a superior tool for α-thalassemia gene detection due to its high specificity, sensitivity, and ability to process large volumes of samples effectively.
[Application of DNA Microarray in Genetic Mutation Detection in Patients with Thalassemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
October 2021
Article Synopsis
- The study aimed to assess the effectiveness of using dried blood spots for detecting thalassemia gene mutations in patients through microarray technology.
- DNA was extracted from 410 patients' dried blood spots, identifying multiple types of α-thalassemia and β-thalassemia mutations prevalent in China.
- Results showed an 87.07% positive detection rate, with the most common mutations being heterozygous deletions for α-thalassemia and CD41-42 for β-thalassemia, demonstrating the efficiency of the microarray method for simultaneous detection of both types.
Background: This meta-analysis was conducted in order to understand the clinical efficacy of stent insertion with high-intensity focused ultrasound (HIFU) ablation for the treatment of malignant biliary obstruction (MBO).
Methods: The Pubmed, Embase, and Cochrane Library databases were searched for all relevant studies published through July 2020. The meta-analysis was conducted using RevMan v5.
Pluripotent stem cell (PSC) cultures form an integral part of biomedical and medical research due to their capacity to rapidly proliferate and differentiate into hundreds of highly specialized cell types. This makes them a highly useful tool in exploring human physiology and disease. Genomic editing of PSC cultures is an essential method of attaining answers to basic physiological functions, developing in vitro models of human disease, and exploring potential therapeutic strategies and the identification of drug targets.
View Article and Find Full Text PDFRheumatoid arthritis (RA) is a chronic systemic autoimmune disease, which has as its primary target, the synovial tissues and articular cartilage. The current pharmacological treatment of RA includes non-steroidal anti-inflammatory drugs, corticosteroids, and disease-modifying anti-rheumatic drugs. Newer biological agents that work by inactivation of proinflammatory cytokines are available for treatment of RA.
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