Epidemiology of pathogens and drug resistance of ventilator-associated pneumonia in Chinese neonatal intensive care units: a meta-analysis.

Background: Ventilator-associated pneumonia (VAP) is a common and serious problem in intensive care units. However, limited literature has been reviewed to synthesize the findings about the incidence, case fatality rate, pathogen distribution, and drug resistance of neonatal VAP in China.

Methods: A search of electronic databases was undertaken to identify the incidence, case fatality rate, pathogen distribution, and drug resistance of neonatal VAP based on the inclusion and exclusion criteria.

Anthraquinones from the roots of Prismatomeris tetrandra.

A new anthraquinone compound, 1,3-dihydroxy-6-methoxy-2-methoxymethyl-9,10-anthraquinone (1), along with four known analogues (2-5) were isolated from the roots of Prismatomeris tetrandra. Their structures were elucidated on the basis of spectroscopic analysis. Among these compounds, lucidin omega-methyl ether (4) and lucidin omega-ethyl ether (5) were isolated from this genus for the first time.