Rational Synthesis of Functionalized Covalent Organic Frameworks via Four-Component Reaction.

The construction of function-oriented covalent organic frameworks (COFs) remains a challenge as it requires simultaneous consideration of diversified structures, robust linkage, and tailorable functionalities. Herein, we report the rational synthesis of functionalized COFs via a four-component reaction strategy. Through the four-component Debus-Radziszewski reaction, 11 -substituted imidazole-based COFs with diversified structures were facilely constructed from readily available building blocks.

Effectiveness of the attachment position in molar intrusion with clear aligners: a finite element study.

Objective: To evaluate the biomechanical effects of different attachments' position for maxillary molar intrusion with clear aligner treatment by finite element analysis.

Methods: Cone-beam computed tomography images of a patient with supra-eruption of the maxillary second molars were selected to construct three-dimensional models of the maxilla, periodontal ligaments, dentition, and clear aligner. The models were divided into four groups depending on the attachment location on the first molar: (1) no attachment (NA), (2) buccal attachment (BA), (3) palatal attachment (PA), and (4) bucco-palatal attachment (BPA).

Doping Free and Amorphous NiO Film via UV Irradiation for Efficient Inverted Perovskite Solar Cells.

High crystallization and conductivity are always required for inorganic carrier transport materials for cheap and high-performance inverted perovskite solar cells (PSCs). High temperature and external doping are inevitably introduced and thus greatly hamper the applications of inorganic materials for mass production of flexible and tandem devices. Here, an amorphous and dopant-free inorganic material, Ni -rich NiO , is reported to be fabricated by a novel UV irradiation strategy, which is facile, easily scaled-up, and energy-saving because all the processing temperatures are below 82 ℃.

Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and Dental Pulp Stem Cells (DPSCs) Display a Similar Profile with Pericytes.

Background: Pericytes play an important role in forming functional blood vessels and establishing stable and effective microcirculation, which is crucial for vascular tissue engineering. The slow ex vivo expansion rate, limited proliferative capacity, and variability of tissue-specific phenotypes would hinder experimental studies and clinical translation of primary pericytes. In this study, the angiogenic and pericyte functions of stem cells from human exfoliated deciduous teeth (SHEDs) and postnatal human dental pulp stem cells (DPSCs) were investigated.

Pyrimidazole-Based Covalent Organic Frameworks: Integrating Functionality and Ultrastability via Isocyanide Chemistry.

Development of new chemistry to simultaneously meet the demands for topology, connectivity, and functionality is highly desired in the research area of covalent organic frameworks (COFs). We explore herein the isocyanide chemistry so as to establish a facile paradigm to integrate functionality and ultrastability in COFs. Using the representative Groebke-Blackburn-Bienaymé (GBB) reaction based on isocyanide chemistry, we are able to construct a series of pyrimidazole-based COFs in one step from isocyanide, aminopyridine, and aldehyde monomers.

Constructing Robust Covalent Organic Frameworks via Multicomponent Reactions.

Methodology development of robust linkages is fundamentally important for the synthesis and application of covalent organic frameworks (COFs). We report herein a new strategy based on multicomponent reactions (MCRs) to construct ultrastable COFs. With the one-pot formation of five covalent bonds in each cyclic joint, a series of imidazole-linked COFs were robustly constructed through the Debus-Radziszewski MCR from three easily available components.

[Outcome of one-visit and multiple-visit root canal treatment for cracked tooth with pulpitis: a meta analysis].

Purpose: To compare the treatment effect between one-visit and multiple-visit endodontic treatment for cracked tooth with pulpitis.

Methods: The literatures published before 2016-06-01 regarding to one-visit and multiple-visit root canal treatment for cracked tooth with pulpitis were searched through MEDLINE, CNKI, VIP, Wanfang Database et al. Then the included studies were chosen according to the inclusion criteria.

[Effect of transfected EphB4 on osteogenic differentiation in stem cells from human exfoliated deciduous teeth].

Purpose: To evaluate the effect of stem cells from human exfoliated deciduous teeth (SHED) transfected with EphB4 gene in regulating osteogenic differentiation.

Methods: Human dental pulp tissue were harvested from extracted deciduous teeth and digested by collagenase and dispase. The SHEDs were transfected with transgenic (hEphB4-GFP) vector or empty vector (GFP-vector).

[The mechanism of corticotomy accelerating orthodontic tooth movement in SD rats].

Purpose: To study the influences of corticotomy on orthodontic tooth movement (OTM) and the underlying mechanism in rats.

Methods: Forty-eight female Sprague-Dawley rats were randomly assigned to corticotomy group (Cort, 24 rats) or sham-corticotomy group (Sham, 24 rats). All rats were subjected OTM after corticotomy or sham surgery.

[Quality of life and its influential factors of children and adolescents with congenital cleft lip and palate].

Purpose: To investigate the quality of life of children undergoing clef lip or and palate repair as well as the influential factors of the quality of life, and provide theoretical foundation for future studies such as psychological interventions.

Methods: Totally 164 children and young adolescent patients with cleft lip and palate undergoing maxillofacial surgery and orthodontic treatment in Xuzhou Stomatology Hospital were selected as experimental group, and 102 normal children and young adolescents were selected as control group. Both groups were investigated by general information questionnaire and child and adolescents' quality of life scale (CAQOL).

What do patients expect from treatment with Dental Implants? Perceptions, expectations and misconceptions: a multicenter study.

Objective: While research in terms of patient-centered care in implant therapy is growing, few studies have investigated patients' initial perceptions prior to consultation with the implant dentist. The aim of this cross-sectional study was to capture patients' initial information level, perceptions, as well as expectations from the implant therapy.

Method: A 34-item questionnaire was developed to investigate patients' preoperative information, perceptions and expectations from treatment with Dental Implants.

[Coculture of stem cells from the apical papilla and human umbilical vein endothelial cells enhances the angiogenic potential of dental pulp tissues].

Purpose: To observe the effect of coculture of stem cells from the apical papilla (SCAPs) and human umbilical vein endothelial cells (HUVECs) on the angiogenic potential of dental pulp tissues.

Methods: SCAPs were incubated in osteo/odontogenic, adipogenic, neurogenic induction medium and α-MEM medium, whose multilineage differentiation capacities were confirmed using alizarin red staining, oil red O staining and βIII-tubulin immunofluorescent staining. The tubular length, branching points number and junctional areas were detected after 3, 6, 9 h since cells were seeded onto matrigel, and the data was analyzed using SPSS 16.

Morphological analysis of apical foramen over-instrumented by three rotary NiTi systems.

Objective: To evaluate morphological changes of the apical surface after root canal preparation with 1 mm beyond the apical foramen using ProTaper Universal (PTU) files, K3 files and Twisted files (TF), respectively.

Methods: Seventy teeth with a centered apical foramen and 70 teeth with a deviated apical foramen were included as group A and group B respectively. In each group, 20 teeth were randomly assigned for root canal preparation with PTU, K3 and TF files, respectively; the remaining 10 teeth were used as the control group without any preparation.

[Comparative analysis of the relationship between of chronic periodontitis patients' compliance and clinical efficacy].

Objective: To evaluate the effect of patients' compliance on clinical parameters in patients with chronic periodontitis during periodontal maintenance therapy period.

Methods: Chronic periodontitis patients who had completed non-surgical periodontal basic treatment were incorporated into the periodontal maintenance therapy(PMT). Clinical examination was performed in the baseline and each quarterly recall, over 3-year period.

[The influential factors of patients' compliance with supportive periodontal therapy].

Purpose: To discuss the influential factors of patients' compliance with chronic periodontitis during supportive periodontal therapy (SPT) period and the counter measures.

Methods: Chronic periodontal patients completing intial non-surgical therapy with SPT were investigated with a self-designed questionnaire after 2 years by outpatient follow-up and telephone interviews to obtain information for analysis.

Results: One hundred and one effective scales were collected.

[The application of problem-based learning and case-based study in the practice teaching of clinical prosthodontics courses].

Purpose: To study the effect of problem-based learning(PBL) and case-based study(CBS) for knowledge acquisition and clinical performance in the practice teaching of clinical prosthodontics courses.

Methods: Consecutive cohorts of year 2 clinical students taught using a traditional prosthodontics curriculum (students who practiced in Xuzhou Stomatological Hospital from June 2007 to June 2008, n=30) and a PBL and CBS curriculum (who practiced in Xuzhou Stomatology hospital from June 2008 to June 2009, n=30) were compared.Students completed an end-of-attachment examination and a questionnaire in which students were requested to rate themselves on 7 competencies.

[Foreign stone retaining in right post-maxillary molar area for 10 years causing limitation of mouth opening: report of one case].

It is common to see a foreign body retained in the soft tissues of oral and maxillofacial region. However, a foreign body retaining in oral and maxillofacial region for more than 10 years and resulting in limitation of mouth opening is rare. This paper reported a 52-year-old man, who had limitation of mouth opening for more than 1 year caused by a stone retaining in right post-maxillary molar area for 10 years.

[Clinical study of cancellous iliac bone graft in cleft alveolar repair].

Purpose: To analyze the factors affecting the effect of cleft alveolar repair.

Methods: 21 patients with alveolar cleft who were treated in our hospital between 2003-2007 were included in this study. The factors that affected the cleft alveolar repair such as patient's age, cleft type, surgical method, source of bone were analyzed accordingly.

[Treatment of primary trigeminal neuralgia with radiofrequency thermogangliocoagulation: Report of 152 consecutive cases].

Purpose: To evaluate the clinical results of primary trigeminal neuralgia treated by RFT and investigate the methods to manage complications.

Methods: 152 cases of primary trigeminal neuralgia were collected from 2001 to 2004, a retrospective study was undertaken to analyze the clinical characters such as effective rate, ineffective rate and the rate of complications of patients treated with RFT.

Results: The average age of the 152 cases was 48.

[Clinical observation of the height of the alveolar after bone grafting in cleft alveolar repair in various ages.].

Purpose: To evaluate the changes of transplanted bones after cancellous iliac bone grafting in cleft alveolar repair in various ages.

Methods: The patients were divided into A and B groups according to their canine eruption. The changes of alveolar height in grafting regions were examined by clinical follow up and radiographs after the cancellous iliac bone grafting in cleft alveolar repair.