Publications by authors named "Peng-He Wang"
Objectives: Contezolid acefosamil is a novel O-acyl phosphoramidate prodrug of contezolid. In the current study, we aimed to systemically evaluate the efficacy of contezolid acefosamil against infections caused by multiple Gram-positive pathogens, and compare the efficacy of the prodrug by oral and intravenous administrations.
Methods: The in vivo pharmacodynamic efficacy of contezolid acefosamil was evaluated in mouse models of systemic (with five S.
[Progress on femorotibial mechanical axis of total knee arthroplasty].
Zhongguo Gu Shang
February 2021
Article Synopsis
- Femorotibial mechanical axis (FTMA) is crucial for successful total knee arthroplasty (TKA), with the ideal alignment considered to be neutral FTMA ± 3°, which improves joint function and longevity of prosthesis.
- * Recent advancements in surgical technology have improved the accuracy of FTMA alignment, but there hasn't been a significant enhancement in clinical outcomes post-surgery.
- * Some researchers argue that achieving neutral FTMA may not be necessary for better results, suggesting alternative alignment methods that consider patient-specific factors and other joint interactions can lead to improved clinical effects.