Single-center clinical experience of extended sleeve lobectomy (ESL) versus standard sleeve lobectomy (SL).

Background: Sleeve lobectomy (SL) and extended SL (ESL), which aim to preserve pulmonary function and enhance the quality of life of patients while ensuring oncological outcomes, are valuable surgical options for the treatment of centrally located non-small cell lung cancer (NSCLC). This study aimed to compare perioperative adverse events and long-term survival between SL and ESL in NSCLC patients, providing a comprehensive review of surgical outcomes, complications, and survival to assess the roles of SL and ESL in thoracic oncology.

Methods: This single-center retrospective study assessed the outcomes of NSCLC patients who underwent SL or ESL from June 2014 to January 2022.

A case report of cStage IIIB squamous cell lung carcinoma completely resected after downstaging with neoadjuvant therapy.

Background: The most effective method and length of time for administering adjuvant immunotherapy after surgery for non-small cell lung cancer (NSCLC) are still unknown. Various clinical trials have utilized diverse strategies for adjuvant treatment. In this case, we explore the potential benefits of neoadjuvant immunotherapy combined with chemotherapy in managing locally advanced lung squamous carcinoma, which often poses challenges for treatment.

Extended autofocusing in dual-wavelength digital holography.

In single-wavelength digital holography (DH), the phase wrapping phenomenon limits the total object depth that can be measured due to the requirement for well-resolved phase fringes. To address this limitation, dual-wavelength DH is proposed, enabling measurement of much deeper objects. In single-wavelength DH, because the object depth is limited, the depth of focus (DOF) of DH's optical system at a reconstruction distance is sufficient to cover the object depth.

A Herd-Foraging-Based Approach to Adaptive Coverage Path Planning in Dual Environments.

Coverage path planning (CPP) is essential for robotic tasks, such as environmental monitoring and terrain surveying, which require covering all surface areas of interest. As the pioneering approach to CPP, inspired by the concept of predation risk in predator-prey relations, the predator-prey CPP (PPCPP) has the benefit of adaptively covering arbitrary bent 2-D manifolds and can handle unexpected changes in an environment, such as the sudden introduction of dynamic obstacles. However, it can only work in bounded environment and cannot handle tasks in unbounded one, e.

Sonocatalytic degradation of ciprofloxacin using hydrogel beads of TiO incorporated biochar and chitosan.

Pharmaceuticals are necessary to be removed from environment. Herein TiO incorporated biochar made from pyrolysis of agricultural wastes was encapsulated into chitosan to obtain a novel hydrogel beads. This hydrogel beads executed a dual role as both adsorbent and sonocatalyst, which proved to be suitable for the removal of antibiotic ciprofloxacin (CIP) from water.

Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis.

To explore the function of transcription factor 3 (TCF3) on the proliferation and apoptosis of Burkitt lymphoma cells and its mechanism. qRT-PCR was performed to determine the expression of TCF3, histone deacetylase 3 (HDAC3), and microRNA-101 (miR-101) in the Burkitt lymphoma (BL) tumor tissues and lymph node tissues with reactive lymph node hyperplasia (RLNH). We found that the expression of TCF3 and HDAC3 was up-regulated in BL tumor tissues and lymphoma cells, and the miR-101 expression was down-regulated.

Monoterpenoid signals and their transcriptional responses to feeding and juvenile hormone regulation in bark beetle Ips hauseri.

Hauser's engraver beetle, Ips hauseri, is a serious pest in spruce forest ecosystems in Central Asia. Its monoterpenoid signal production, transcriptome responses and potential regulatory mechanisms remain poorly understood. The quality and quantity of volatile metabolites in hindgut extracts of I.

CircKDM4C upregulates P53 by sponging hsa-let-7b-5p to induce ferroptosis in acute myeloid leukemia.

To investigate the role of circKDM4C in acute myeloid leukemia (AML), the expression of circKDM4C, hsa-let-7b-5p, and P53 was measured by qRT-RCR. AML cell lines(K-562 and HL-60) were transfected correspondingly and investigated for cell proliferation, migration, and invasion abilities by CCK-8, colony formation, transwell, and wound healing assays, respectively. The levels of P53, ACSL4, PTGS2, GPX4, and FTH1 in the K-562, and HL-60 cells were measured by western blotting.

Depressive symptom-associated IL-1β and TNF-α release correlates with impaired bronchodilator response and neutrophilic airway inflammation in asthma.

Background: Depressive symptoms worsen asthma outcomes; however, the mechanism remains largely unexplored.

Objective: This study aimed to determine whether depressive symptom-associated immune inflammation correlates with impaired bronchodilator response (BDR) and airway inflammatory phenotypes.

Methods: Eligible adults with asthma (n = 198) underwent clinical assessment, sputum induction and blood sampling.

Degenerate four-wave mixing for measurement of magnetic field using a nanoparticles-doped highly nonlinear photonic crystal fiber.

A novel magnetic field sensor based on the degenerate four-wave mixing (DFWM) technique is theoretically proposed using a AsS-core silica-cladding photonic crystal fiber (PCF). In order to enhance the sensitivity, we put forth a novel design of highly nonlinear PCF where the silica cladding is doped with either Au, Ag, or Al metallic nanoparticles. The effect of volume fraction of the nanoparticles within the cladding and the size of nanoparticles are considered as the control parameters in designing the magnetic field PCF sensor to obtain high sensitivity using this novel DFWM scheme.

Two-step method for creating a gastric tube during laparoscopic-thoracoscopic Ivor-Lewis esophagectomy.

Aim: To introduce a two-step method for creating a gastric tube during laparoscopic-thoracoscopic Ivor-Lewis esophagectomy and assess its clinical application.

Methods: One hundred and twenty-two patients with middle or lower esophageal cancer who underwent laparoscopic-thoracoscopic Ivor-Lewis esophagectomy at Liaoning Cancer Hospital and Institute from March 2014 to March 2016 were included in this study, and divided into two groups based on the procedure used for creating a gastric tube. One group used a two-step method for creating a gastric tube, and the other group used the conventional method.

Magnetic field sensor using tilted fiber grating interacting with magnetic fluid.

A novel magnetic field sensor using tilted fiber Bragg grating (TFBG) interacting with magnetic fluid is proposed and experimentally demonstrated. The TFBG is surrounded by magnetic fluid whose complex refractive index changes with external magnetic field. The guiding properties of cladding modes excited by the TFBG are therefore modulated by the external magnetic field.

Magneto-optical fiber sensor based on magnetic fluid.

A novel magnetic field fiber sensor based on magnetic fluid is proposed. The sensor is configured as a Sagnac interferometer structure with a magnetic fluid film and a section of polarization maintaining fiber inserted into the fiber loop to produce a sinusoidal interference spectrum for measurement. The output interference spectrum is shifted as the change of the applied magnetic field strength with a sensitivity of 16.

Magneto-optic fiber Sagnac modulator based on magnetic fluids.

A magneto-optic modulator with a magnetic fluid film inserted into an optical fiber Sagnac interferometer is proposed. The magnetic fluid exhibits variable birefringence and Faraday effect under external magnetic field that will lead to a phase difference and polarization state rotation in the Sagnac interferometer. As a result, the intensity of the output light is modulated under the external magnetic field.