Publications by authors named "Peng Yi"

Bacterial infections and antibiotic resistance represent significant global public health challenges, necessitating the development of innovative antibacterial agents with targeted delivery capabilities. Our study utilized macrophages' natural ability to recognize bacteria and the increased reactive oxygen species (ROS) at infection sites to develop a novel nanoparticle for targeted delivery and controlled release. We prepared bacteria-activated macrophage membranes triggered by Staphylococcus aureus (Sa-MMs), which showed significantly higher expression of Toll-like receptors (TLRs), compared to normal macrophage membranes (MMs).

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Background: Probiotics, which are beneficial to the host, have been shown to benefit the health of cats. Lactic acid bacteria (LAB) are commonly used probiotics, but most strains used for cats are not derived from cats, leading to reduced efficacy and poor adaptation to cats. The objective was to identify LAB with promising probiotic potential specific to cats.

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Objectives: Extensive-stage small cell lung cancer (ES-SCLC) suffering from brain metastases (BM) has a poor prognosis and lacks effective treatment selection. In this study, we explored the efficacy and safety of combination treatment of albumin-bound paclitaxel (nab-ptx), anlotinib, and PD-1/L1 inhibitors for such special population.

Methods: A total of 55 patients diagnosed with ES-SCLC and BM were enrolled in this retrospective study.

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Fused silica with surface structures has potential applications in microfluidic, aerospace and other fields. To fabricate structures with high dimensional accuracy and surface quality is of paramount importance. However, it is indeed a challenge to strike a balance between accuracy and efficiency at the same time.

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  • Large shear deformations can cause changes in crystal structures, but understanding the detailed processes behind these changes has been challenging for scientists.
  • In this study, researchers observe the transformation of square lattices to triangular lattices in thin-film colloidal crystals under shear strain, achieving detailed insights into the kinetics at a single-particle level.
  • They find that during the growth of triangular lattice structures, a liquid layer forms around the nuclei, influenced by localized shear strain, supporting the theoretical idea of "virtual melting" at the crystalline interface.
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Introduction: The effectiveness and tolerability of triple therapy, which combines regorafenib, a programmed death 1 (PD-1) inhibitor, and transarterial chemoembolization (TACE), were compared to dual therapy consisting of regorafenib and a PD-1 inhibitor in patients with advanced hepatocellular carcinoma (HCC).

Methods: A retrospective analysis was conducted on patients with advanced HCC who underwent second-line therapy from March 2019 to June 2022 at multiple centers. Patients were stratified into two groups: dual therapy (comprising regorafenib and a PD-1 inhibitor) and triple therapy (consisting of regorafenib, a PD-1 inhibitor, and TACE).

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AlN, with its ultra-wide bandgap, is highly attractive for modern applications in deep ultraviolet light-emitting diodes and electronic devices. In this study, the surface and cross-sectional properties of AlN films grown on flat and nano-patterned sapphire substrates are characterized by a variety of techniques, including photoluminescence spectroscopy, high-resolution X-ray diffraction, X-ray photoelectron spectroscopy, ultraviolet photoelectron spectroscopy, and Raman spectroscopy. The results indicate that different sapphire substrates have minimal impact on the photoluminescence spectrum of the epitaxial films.

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Background: The Scottish Inflammatory Prognostic Score (SIPS), an innovative scoring system, has emerged as a promising biomarker for predicting patient outcomes following cancer therapy. This study aimed to evaluate the value of SIPS as a prognostic indicator following hepatectomy in patients with hepatocellular carcinoma (HCC).

Methods: This retrospective study included 693 HCC patients who underwent hepatectomy.

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Carbonaceous materials have been considered the most promising anode in sodium-ion batteries (SIBs) due to their low cost, good electrical conductivity, and structural stability. The main challenge of carbonaceous anodes prior to their commercialization is low initial coulomb efficiencies, derived from a lack of an efficient technique to reveal a fundamental comprehension of sodium storage mechanisms. Here, the direct observation of quasi-Na metallic clusters in carbonaceous anodes during cycling through in situ XRD is reported.

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  • Metal organic frameworks (MOFs) are highly porous materials with customizable nanostructures, making them useful in various energy and environmental applications, including batteries, catalysts, and water purification.
  • One-dimensional (1D) MOFs are particularly interesting due to their unique structures, prompting researchers to improve synthesis methods for these materials.
  • The review covers the preparation of 1D MOFs, their properties related to their structures, and future outlooks on their use in energy and environmental technology.
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This study established an on-line SFE-SFC-MS/MS method for the determination of mefentrifluconazole (MFZ) enantiomers and pyraclostrobin (PY) in mango and mango juice. Key parameters of SFC separation and SFE extraction have been optimized for high efficiency, sensitivity, and environmental friendliness. Enthalpy controlled enantioseparations of MFZ were recognized by thermodynamic analysis.

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Conductive polymer foam (CPF) with excellent compressibility and variable resistance has promising applications in electromagnetic interference (EMI) shielding and other integrated functions for wearable electronics. However, its insufficient change amplitude of resistance with compressive strain generally leads to a degradation of shielding performance during deformation. Here, an innovative loading strategy of conductive materials on polymer foam is proposed to significantly increase the contact probability and contact area of conductive components under compression.

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This study aims to optimize surface electromyography-based gesture recognition technique, focusing on the impact of muscle fatigue on the recognition performance. An innovative real-time analysis algorithm is proposed in the paper, which can extract muscle fatigue features in real time and fuse them into the hand gesture recognition process. Based on self-collected data, this paper applies algorithms such as convolutional neural networks and long short-term memory networks to provide an in-depth analysis of the feature extraction method of muscle fatigue, and compares the impact of muscle fatigue features on the performance of surface electromyography-based gesture recognition tasks.

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  • An improved Gaussian Mixture Model (GMM)-based user clustering algorithm enhances the performance of NOMA-assisted integrated sensing and communication (ISAC) systems in multi-user scenarios.
  • The algorithm uses the Sum of Squared Errors (SSE) to improve clustering accuracy and introduces direction weight factors to reduce interference and optimize user group alignment.
  • Simulation results demonstrate that this new approach increases user spectral efficiency by 4.3% and enhances base station beam intensity by 5.4% compared to traditional ISAC systems.
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  • * In a study with fifteen patients, one side of the mouth received just SRP, while the other side had both SRP and the Nd:YAG laser, with improvements measured after six weeks.
  • * Results showed that the combination treatment led to significant improvements in gum health, indicated by reduced probing depth and inflammation, but did not change the overall types of bacteria present in the gums.
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In this rapidly evolving era of multimodal generation, diffusion models exhibit impressive generative capabilities, significantly enhancing the realm of creative image synthesis by intricately textual prompts. Yet, their effectiveness is limited in certain niche sectors, like depicting Chinese ancient architecture. This limitation is primarily due to the insufficient data that fails to encompass the unique architectural features and corresponding text information.

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Background: Maternal depression and anxiety during pregnancy are significant public health concerns commonly reported worldwide among pregnant women. This study aimed to investigate the impact of anxiety and depression on thyroid function, pregnancy outcomes, and sleep quality among pregnant women with hypothyroidism in the later stages of pregnancy.

Methods: Eighty cases of pregnant women with hypothyroidism in late pregnancy who were treated at Zhangjiakou First Hospital from January 2021 to October 2023 were selected for this retrospective study.

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Challenges in obtaining stable nitrite have impeded the use of anammox in municipal wastewater treatment. This study explored the feasibility of using sludge fermentation products as carbon source and selective nitrification inhibitor to supply nitrite via partial nitrification (PN) and partial denitrification (PD). PD was initiated within 15 days, achieving nitrite transformation rate of over 90 % with a carbon/nitrogen ratio of 3 and a reaction time of 0.

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The century-old inverted Keggin ion has been revisited in an effort to unleash its potential in the structural engineering and functional development of polyoxomolybdates (POMos). Over the past hundred years, attempts to program the metal-oxo scaffold of inverted Keggins have been conducted continually but without any success. In this work, a structurally inert, inverted Keggin-type POMo could finally be altered by means of a binary heterogroup-templated approach, resulting in the successful isolation of two lacunary species.

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Juvenile idiopathic arthritis (JIA) is the most prevalent pediatric rheumatic disease. While disease-modifying antirheumatic drugs (DMARDs), especially biologics, have greatly transformed the management of JIA, there remain some unmet medical needs that require new treatment options. The objective of this work was to describe and apply a modeling and simulation approach to extrapolate upadacitinib efficacy from the adult diseases, rheumatoid arthritis (RA) and psoriatic arthritis (PsA), to their respective pediatric diseases, polyarticular course JIA (pcJIA), and juvenile PsA (JPsA).

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  • The monolayer MoSiN shows great environmental stability, moderate band gap, and excellent mechanical properties, but its low carrier mobility restricts its use in field-effect transistors (FETs).
  • This study investigates a new family of β-phase MXN monolayers, revealing they possess strong stability and varying band gaps, with MoSiN, MoGeN, WSiN, and WGeN identified as potential semiconductors.
  • WGeN stands out with impressive anisotropic charge transport and high carrier mobility, making these new materials promising for expanding the 2D MXZ material family and improving FET applications.
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Emulsified asphalt mixtures' cold mix and paving features facilitate asphalt pavements in fulfilling dual-carbon and energy-saving demands. Anionic emulsifiers can enhance emulsion stability, ensure uniform dispersion of oil and water, possess good decompression viscosity, thickening, and lubricating properties, and maintain good stability under acidic conditions. Nevertheless, anionic emulsified asphalt is restricted in engineering applications due to problems like its storage stability.

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