Mechanisms Underlying the Antidepressant Effect of Acupuncture the CaMK Signaling Pathway.

The CaMK pathway has been proven to play an important role in regulating cognitive function and emotional response. Acupuncture through the CaMK pathway improves depression-like behavior and the molecular mechanism related to its antidepressant remains to be explored. In this study, we aimed to determine whether the ability of acupuncture at Baihui (GV20) and Shenting (GV24) points to treat depression is related to the regulation of key proteins in the CaMK pathway.

Assessment of the abstract reporting of systematic reviews of dose-response meta-analysis: a literature survey.

Background: There is an increasing number of published systematic reviews (SR) of dose-response meta-analyses (DRMAs) over the past decades. However, the quality of abstract reporting of these SR-DRMAs remains to be understood. We conducted a literature survey to investigate the abstract reporting of SR-DRMAs.

Improving the quality of reporting of systematic reviews of dose-response meta-analyses: a cross-sectional survey.

Background: Dose-response meta-analysis (DRMA) is a useful tool to investigate potential dose-response relationship between certain exposure or intervention and the outcome of interest. A large number of DRMAs have been published in the past several years. However, the standard of reporting for such studies is not known.

The methodological quality of dose-response meta-analyses needed substantial improvement: a cross-sectional survey and proposed recommendations.

Objectives: To investigate methodological quality of published dose-response meta-analysis (DRMA) and explore study characteristics associated with the quality.

Study Design And Setting: We searched three databases for published DRMAs and used a modified AMSTAR (15 items) checklist to assess the methodological quality. We summarized the compliance of those DRMAs to the AMSTAR items and used multivariable regression analysis to explore the association between prespecified study characteristics with the overall methodological quality.

The risk of lung cancer among cooking adults: a meta-analysis of 23 observational studies.

Purpose: Cooking has been regarded as a potential risk factor for lung cancer. We aim to investigate the evidence of cooking oil fume and risk of lung cancer.

Methods: Medline and Embase were searched for eligible studies.

Literature review on clinical decision support system reducing medical error.

Objectives: Quite a number of studies on clinical decision support systems (CDSS) have been published in recent years to assess the characteristics and architecture of CDSS and evaluate the effects of CDSS on clinical work. However, until now there have been no relevant studies to investigate the quantity of these, and their contribution to present day thinking. The aim of this study was to explore the areas of theme, and the study design of research on CDSS in literature published in English and Chinese-language journals.