Publications by authors named "Penelope L Nayudu"

The excellent adaptability of Callithrix jacchus to life in captivity presents advantages in comparison to other nonhuman primates that are used in experimental models for biomedical research, which explains the increasing scientific interest in investigating the anatomical characteristics of this species. Owing to the relative scarcity of publications on the descriptive morphology of the heart of C. jacchus, the aim of this study was to quantify the presence of collagen in the left and right ventricular myocardium using modified picrosirius red and acid fuchsine colorimetric assays.

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Background: Congenital fused labia (CFL) is defined as a failure or significant delay in the opening of the juvenile sealed labia majora. This phenotype is known to be variably common in adult captive female marmosets but has never been investigated in detail before.

Materials And Methods: Here, we define, describe and quantify the variations in the degree of closure of the vulva in 122 captive marmosets (Callithrix jacchus) from 1.

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Background: The common marmoset (Callithrix jacchus) is of interest for reproductive studies because of their high and variable fertility in captivity. However, to understand this variability, much basic information still needs to be gathered. This study is the first to characterize marmoset semen comparing a German and a Brazilian colony.

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Background: Beta-microseminoprotein, an abundant component in prostatic fluid, is encoded by the potential tumor suppressor gene MSMB. Some New World monkeys carry several copies of this gene, in contrast to most mammals, including humans, which have one only. Here we have investigated the background for the species difference by analyzing the chromosomal organization and expression of MSMB in the common marmoset (Callithrix jacchus).

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The semen coagulum proteins have undergone substantial structural changes during evolution. In primates, these seminal vesicle-secreted proteins are known as semenogelin I (SEMG1) and semenogelin II (SEMG2). Previous studies on the common marmoset (Callithrix jacchus) showed that ejaculated semen from this New World monkey contains semenogelin, but it remained unclear whether it carries both genes or only SEMG1 and no SEMG2, like the closely related cotton-top tamarin (Saguinus oedipus).

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Human seminal plasma contains high concentrations of prostatic acid phosphatase (PAP), prostate-specific antigen (PSA), beta-microseminoprotein (MSP), semenogelin I (SgI), and semenogelin II (SgII), whereas only PAP and MSP are present in rodents. In order to gain a better understanding of the evolution and function of semen proteins, we have studied ejaculates from the common marmoset (Callithrix jacchus)-a New World monkey. Semen samples were analyzed with SDS-PAGE, Western blotting, and isoelectric focusing.

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An important limiting factor in assisted reproduction treatment success rates is oocyte quality. In spite of improved results through several important innovations, the pregnancy rate per collected oocyte remains far too low. In order to improve this situation, it is necessary to learn more about fundamental factors modulating follicular development patterns.

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