Optimising β-Ti21S Alloy Lattice Structures for Enhanced Femoral Implants: A Study on Mechanical and Biological Performance.

The metastable β-Ti21S alloy exhibits a lower elastic modulus than Ti-6Al-4V ELI while maintaining high mechanical strength and ductility. To address stress shielding, this study explores the integration of lattice structures within prosthetics, which is made possible through additive manufacturing. Continuous adhesion between the implant and bone is essential; therefore, auxetic bow-tie structures with a negative Poisson's ratio are proposed for regions under tensile stress, while Triply Periodic Minimal Surface (TPMS) structures with a positive Poisson's ratio are recommended for areas under compressive stress.

Diabetes Care in the School Setting: A Statement of the American Diabetes Association.

Diabetes is a prevalent chronic disease in school-age children. To keep students with diabetes safe at school, support their long-term health, prevent complications, and ensure full participation in all school activities, proper monitoring of and response to glucose levels must be attended to throughout the school day and during all school-sponsored activities. Care coordination among the family, school, and diabetes health care professionals is critical.

Ranking occupations by their proximity to workers' profiles.

Information friction makes it difficult for job seekers to find new employment opportunities. We propose a method for providing individual-specific occupation recommendations by ranking occupations based on their proximity to the worker's profile. We identify a set of twelve skills, abilities and work styles that capture the worker-oriented requirements of all occupations and discuss how to measure these items using online questions and tasks.

[Reduction of prescription error and its adverse effects in the pediatric intensive care area].

Introduction: Prescription is the node of medication management and use that most frequently presents medication errors, according to various studies. This study aims to analyze prescriptions before and after the incorporation of a multidisciplinary round in the pediatric intensive care area and its implication in the occurrence of adverse drug events.

Methods: This is an uncontrolled before and after study.

Virtual insulin pump initiation is safe effective in children adolescents with type 1 diabetes.

Objective: There is no head-to-head comparison of the safety and efficacy of virtual versus in-office insulin pump initiation for youth with type 1 diabetes in the US. The study's aim was to determine the safety and efficacy of virtual versus in-office pump initiation in pediatric type 1 diabetes.

Research Design And Methods: A longitudinal retrospective study of 112 subjects: 65% (n=73), ages 11.

Patient safety culture in South America: a cross-sectional study.

Background: Every year, millions of patients suffer injuries or die due to unsafe and poor-quality healthcare. A culture of safety care is crucial to prevent risks, errors and harm that may result from medical assistance. Measurement of patient safety culture (PSC) identifies strengths and weaknesses, serving as a guide to improvement interventions; nevertheless, there is a lack of studies related to PSC in Latin America.

Metrological characterization of porosity graded β-Ti21S triply periodic minimal surface cellular structure manufactured by laser powder bed fusion.

The design of a functionally graded porous structure (FGPS) for use in prosthetic devices is crucial for meeting both mechanical and biological requirements. One of the most commonly used cellular structures in FGPS is the triply periodic minimal surface (TPMS) structure due to its ability to be defined by implicit equations, which allows for smooth transitions between layers. This study evaluates the feasibility of using a novel β-Ti21S alloy to fabricate TPMS-based FGPS.

Manufacturability of functionally graded porous β-Ti21S auxetic architected biomaterials produced by laser powder bed fusion: Comparison between 2D and 3D metrological characterization.

Functionally graded porous structures (FGPSs) are attracting increasing interest in the manufacture of prostheses that benefit from lower stiffness and optimized pore size for osseointegration. In this work, we explore the possibility of employing FGPSs with auxetic unit cells. Their negative Poisson's ratio was exploited to reduce the loss of connection between prosthesis and bone usually occurring in standard implant loaded under tension and therefore undergoing lateral shrinking.

Ultra-Processed Food Consumption and Incidence of Obesity and Cardiometabolic Risk Factors in Adults: A Systematic Review of Prospective Studies.

Ultra-processed foods (UPF) are energy-dense, nutritionally unbalanced products, low in fiber but high in saturated fat, salt, and sugar. Recently, UPF consumption has increased likewise the incidence of obesity and cardiometabolic diseases. To highlight a possible relationship, we conducted a systematic review of prospective studies from PubMed and Web of Science investigating the association between UPF consumption and the incidence of obesity and cardiometabolic risk factors.

Long-term follow-up of nutritional status in children with GLUT1 Deficiency Syndrome treated with classic ketogenic diet: a 5-year prospective study.

Introduction: The classic ketogenic diet (cKD) is an isocaloric, high fat, low-carbohydrate diet that induces the production of ketone bodies. High consumption of dietary fatty acids, particularly long-chain saturated fatty acids, could impair nutritional status and increase cardiovascular risk. The purpose of this study was to evaluate the long-term effects of a 5-year cKD on body composition, resting energy expenditure, and biochemical parameters in children affected by Glucose Transporter 1 Deficiency Syndrome (GLUT1DS).

Reply to Alvarez Stehle, E. Comment on "Leone et al. Association between Mediterranean Diet and Fatty Liver in Women with Overweight and Obesity. 2022, , 3771".

We thank Dr. Elvira Alvarez Stehle [..

Association between Mediterranean Diet and Fatty Liver in Women with Overweight and Obesity.

Obesity is a risk factor for NAFLD. However, not all people with obesity have an excessive intrahepatic fat content. Adherence to a high-quality dietary pattern may also promote liver health in obesity.

Deep brain stimulation for Parkinson's disease in practice: results of the survey by the Italian Neurosurgery Society.

Background: Deep brain stimulation (DBS) is a safe and effective treatment for patients with advanced Parkinson's disease (PD) and many neurosurgical centers in Italy have a DBS program. Considering the prevalence of PD and criteria for DBS implantation, about 3200-10,350 PD patients may benefit from DBS in Italy. The global management of patients underwent DBS is complex and it can be supposed that many differences exist between centers in clinical practice.

Systematic Review on the Potential Effect of Berry Intake in the Cognitive Functions of Healthy People.

The increase in life expectancy poses health challenges, such as increasing the impairment of cognitive functions. Berries show a neuroprotective effect thanks to flavonoids, able to reduce neuroinflammatory and to increase neuronal connections. The aim of this systematic review is to explore the impact of berries supplementation on cognitive function in healthy adults and the elderly.

Appetite ratings and ghrelin concentrations in young adults after administration of a balanced meal. Does sex matter?

Background: Sex-based differences in appetite ratings have been observed previously. Ghrelin is the only known orexigenic peptide hormone. Sex differences in postprandial ghrelin responses may underlie different perceptions of hunger and satiety, but results are conflicting.

[Healthcare-associated harm in adult patients hospitalized in two tertiary care centers in Argentina].

The damage associated with health care is relevant and highly preventable. The Global Trigger Tool is a leading methodology in use for its quantification. Our study aimed to quantify, through this tool, the damage associated with care during hospitalization, characterize the types of damage involved, identify the associated factors and describe the use of the information collected.

Ultra-processed foods and obesity and adiposity parameters among children and adolescents: a systematic review.

Purpose: According to the NOVA classification, ultra-processed foods are products made through physical, biological and chemical processes and typically with multiple ingredients and additives, in which whole foods are mostly or entirely absent. From a nutritional point of view, they are typically energy-dense foods high in fat, sugar, and salt and low in fiber. The association between the consumption of ultra-processed food and obesity and adiposity measurements has been established in adults.

[A strategy to reduce medication prescription error in hospitalized patients].

Prescription errors represent a relevant health problem. This work aims to analyze the medication prescription error in hospitalized patients before and after a multiple intervention. This is a quasi-experimental study of the uncontrolled before-after type.

[Integrated social and health care supported by home telemonitoring in patients with heart failure: the European SmartCare project in the Friuli Venezia Giulia Region].

Background: Home care for patients with chronic diseases and specifically with heart failure (HF) is one of the main challenges of health care for the future. Telemedicine, applied to HF, allows intensive home monitoring of the most advanced patients, improving their prognosis and quality of life. The European SmartCare project was carried out in the Friuli Venezia Giulia (FVG) region with the aim of improving integrated health and social care in patients with chronic non-communicable diseases (CNCD) through home telemonitoring (TM) and promoting self-management and patient empowerment.

Survival of Hospitalized COVID-19 Patients in Northern Italy: A Population-Based Cohort Study by the ITA-COVID-19 Network.

Introduction: COVID-19 case fatality rate in hospitalized patients varies across countries and studies. Reliable estimates, specific for age, sex, and comorbidities, are needed to monitor the epidemic, to compare the outcome in different settings, and to correctly design trials for COVID-19 interventions. The aim of this study was to provide population-based survival curves of hospitalized COVID-19 patients.

Impact of invasive alien plants on native plant communities and Natura 2000 habitats: State of the art, gap analysis and perspectives in Italy.

Invasive alien plants are a major threat to biodiversity and they contribute to the unfavourable conservation status of habitats of interest to the European Community. In order to favour implementation of European Union Regulation no. 1143/2014 on invasive alien species, the Italian Society of Vegetation Science carried out a large survey led by a task force of 49 contributors with expertise in vegetation across all the Italian administrative regions.

A 3D-Printed Ultra-Low Young's Modulus β-Ti Alloy for Biomedical Applications.

The metastable β-Ti21S alloy is evaluated as a potential candidate for biomedical parts. Near fully dense (99.75 ± 0.

Spark Plasma Sintering of Copper Matrix Composites Reinforced with TiB Particles.

The aim of this study is to fabricate a Cu-0.5wt%TiB composite by mechanical alloying (MA) and spark plasma sintering (SPS). Increasing the milling time, the powders are subjected firstly to a severe flattening process and then to intense welding, which promotes the refinement of TiB particles, their uniform dispersion in the metal matrix, and the adhesion between the two constituents.

Overall mortality and causes of death in newly admitted nursing home residents.

Background: In spite of a rapidly ageing population, there is a lack of population-based data on mortality among nursing home residents in Southern Europe.

Aims: To assess mortality rates, their determinants, and causes of death in newly admitted nursing home residents in the Veneto region (northeastern Italy).

Methods: 19,392 subjects aged ≥ 65 years admitted to regional nursing homes during 2015-2017 were recruited in a cohort mortality study based on linked health records.

Measurement of the incidence of care-associated adverse events at the Department of Pediatrics of a teaching hospital.

Introduction: Adverse events may be detected using different screening tools. In the pediatric population, the Pediatric Trigger Tool looks for triggers in the medical record to detect preventable and non-preventable care-associated harm.

Objective: To measure the incidence of adverse events at the Department of Pediatrics using this tool.