Publications by authors named "Pellise F"
Purpose: To determine patient-reported clinical status in a cohort of patients operated on during adolescence for adolescent idiopathic scoliosis (AIS) using Cotrel-Dubousset instrumentation after a minimum follow-up (FU) of 25 years.
Methods: Multicentric cross-sectional observational study. We assessed the clinical status of patients using the lumbar-pain numeric rating scale (NRS), ODI, SRS-22r, SF-36, and EQ-5D-5L.
Purpose: The choice of the best management for Adult Spine Deformity (ASD) is challenging. Health-related quality of life (HRQoL), comorbidities, symptoms and spine geometry, along with surgical risk and potential residual disability play a role, and a definite algorithm for patient management is lacking. Machine learning allows to analyse complex settings more efficiently than other available statistical tools.
View Article and Find Full Text PDFArticle Synopsis
- The paper discusses the importance of structured guidelines for returning to activity after spinal deformity surgery, emphasizing that a consistent approach can improve patient recovery and health outcomes.
- It categorizes diverse patient groups, including early onset scoliosis, adolescent idiopathic scoliosis, young adults, adult spinal deformity, elite athletes, and general sports participants, offering tailored recommendations for each.
- The document stems from an educational webinar and aims to standardize postoperative protocols, enhancing both surgeon practice and overall patient care.
Article Synopsis
- * Methods: Researchers developed 10 critical questions from frequently asked AIS inquiries and had the chatbots respond, then evaluated the accuracy, clarity, and empathy of the answers using a rating system by experienced spine surgeons, while also gathering opinions on AI in healthcare.
- * Results: ChatGPT 4.0 performed the best with 39% 'excellent' ratings, while overall, only 26% of responses were rated 'excellent.' Not
Article Synopsis
- The study aims to determine how rod characteristics, screw density, and cages affect mechanical complications in spinal surgeries compared to patient-related factors and alignment in adult spinal deformity cases.
- Data from 302 patients was analyzed using different statistical models to measure outcomes like pseudarthrosis and screw loosening and understand the impact of surgical techniques versus patient demographics.
- Key findings include that using four rods reduces the risk of pseudarthrosis, postoperative malalignment significantly increases the risk of complications, and high screw density leads to a lower risk of screw loosening, while age has a secondary impact on outcomes.
Article Synopsis
- This study analyzed data from multiple centers to explore how machine learning can help in predicting treatment strategies (surgery vs. conservative) for patients with adult spine deformity (ASD).
- It found that patients whose initial treatment approach matched the machine learning predictions were more likely to reach meaningful clinical improvement, measured by the Minimum Clinically Important Difference (MCID) in various health indices.
- The results indicated that different patient clusters (based on conditions like scoliosis and sagittal imbalance) showed varying success rates in achieving MCID, emphasizing the importance of accurate treatment predictions in improving patient outcomes.
Article Synopsis
- - The study investigates mechanical complications (MCs) in patients with Adult Spinal Deformity (ASD) who are considered well-aligned post-surgery, revealing that alignment alone does not eliminate the risk of these complications.
- - A total of 83 patients aged 55 and older were analyzed, with 40% experiencing at least one MC during an average of 4 years of follow-up, including issues like proximal junctional kyphosis and nonunion of surgical rods.
- - The research utilized a multicenter database to identify and analyze risk factors contributing to MCs through statistical methods like binary logistic regression and ROC curve analysis.
Study Design: Retrospective analysis of a prospective multicenter Adult Spinal Deformity (ASD) registry.
Objective: Assess whether spinal alignment deteriorates post-surgery in absence of mechanical complications and evaluate the long-term outcomes of ASD surgery over a five-year period.
Summary Of Background Data: ASD is prevalent among older adults, leading to significant pain and disability.
Background: The optimal treatment for odontoid fractures in older people remains debated. Odontoid fractures are increasingly relevant to clinical practice due to ageing of the population.
Methods: An international prospective comparative study was conducted in fifteen European centres, involving patients aged ≥55 years with type II/III odontoid fractures.
Article Synopsis
- The study examines six cases of perioperative spinal cord injury (SCI) that occurred during complex adult deformity surgeries, noting their causes, treatments, and outcomes.
- Out of 272 patients from the Scoli-RISK-1 cohort study, 2.2% experienced SCI, with cases occurring both during and after surgery.
- The findings highlight the importance of close postoperative monitoring and timely intervention to prevent lasting neurological damage.
Purpose: To assess, in a large population of Adult Spinal Deformity (ASD) patients, the true interest of varying the upper anchors as a protective measure against Proximal Junctional Kyphosis (PJK), by analyzing and comparing 2 groups of patients defined according to their proximal construct. Another objective of the study is to look for any other factors, radiological or clinical, that would affect the occurrence of the proximal failure.
Methods: Retrospective review of a prospective ASD database collected from 5 centers.
Purpose: The Minimal Clinically Important Difference (MCID) is crucial to evaluate management outcomes, but different thresholds have been obtained in different works. Part of this variability is due to measurement error and influence of the database, both essential for calculating the MCID. The aim of this study was to introduce the association of the ROC method in the anchor-based MCID calculation for ODI, SRS-22r, and SF-36, to objectively set the threshold for the anchor-based MCID in an adult spine deformity (ASD) population.
View Article and Find Full Text PDFStudy Design: Prospective multicenter database post-hoc analysis.
Objectives: Opioids are frequently prescribed for painful spinal conditions to provide pain relief and to allow for functional improvement, both before and after spine surgery. Amidst a current opioid epidemic, it is important for providers to understand the impact of opioid use and its relationship with patient-reported outcomes.
(1) : Previous data show that patients with idiopathic scoliosis (IS) can be classified into two groups according to pain intensity. This paper aims to determine which factors can independently predict the likelihood of belonging to a high-level pain group. (2) : The study used a prospective, multicenter, cross-sectional design.
View Article and Find Full Text PDFBackground: The long-term impact of reoperations following adult spinal deformity (ASD) surgery is still poorly understood. Our aim was to identify the relationship between unplanned reoperation and health-related quality of life (HRQoL) gain at 2 and 5 years of follow-up.
Methods: We included patients enrolled in a prospective ASD database who underwent surgery ≥5 years prior to the start of the study and who had 2 years of follow-up data.
Advancements in non-ionizing methods for quantifying spinal deformities are crucial for assessing and monitoring scoliosis. In this study, we analyzed the observer variability of a newly developed digital tool for quantifying body asymmetry from clinical photographs. Prospective observational multicenter study.
View Article and Find Full Text PDFPurpose: Different methods of sagittal alignment assessment compete for predicting adverse events after adult spinal deformity (ASD) surgery. We wanted to study which method provides greater benefit.
Methods: Retrospective study of 391 patients operated for ASD, with > 6 instrumented levels, fused to the pelvis, and 2 years of follow-up.
Introduction: Poor restoration of pelvic version after adult spinal deformity (ASD) surgery is associated with an increased risk of mechanical complications and worse quality of life. We studied the factors linked to the improvement of postoperative pelvic version.
Materials And Methods: This is a retrospective analysis of a prospective multicenter ASD database.
Study Design: Retrospective registry analysis.
Objective: To examine predictions of individual Scoliosis Research Society-22r (SRS-22r) questions one year after surgery for adolescent idiopathic scoliosis (AIS).
Summary Of Background Data: A precision-medicine approach to AIS surgery will inform patients of the likelihood of achieving particular results from surgery, specifically individual responses to the SRS-22r questionnaire.
Study Design: Retrospective analysis of prospectively collected data.
Objective: To identify the best definition of primary anteverted pelvis in the setting of adult spine deformity (ASD), and to investigate whether this is a pathologic setting that requires surgical correction.
Summary Of Background Data: While pelvic retroversion has been thoroughly investigated, pelvic anteversion (AP) is a far lesser discussed topic.
Purpose: The purpose of this study was to determine the isolated influence of smoking in patient-reported outcome measures (PROMs) for adult spinal deformity (ASD) surgery excluding known tobacco-related complications.
Methods: Retrospective analysis of a prospective multicenter ASD database. Patients operated on ASD with 2 year post-operative follow-up were included.
Introduction: Surgery to correct spinal deformities in scoliosis involves the use of contoured rods to reshape the spine and correct its curvatures. It is crucial to bend these rods appropriately to achieve the best possible correction. However, there is limited research on how the rod bending process relates to spinal shape in adolescent idiopathic scoliosis surgery.
View Article and Find Full Text PDFStudy Design/setting: Retrospective cohort study.
Objective: Assess the extent to which defined risk factors of adverse events are drivers of cost-utility in spinal deformity (ASD) surgery.
Methods: ASD patients with 2-year (2Y) data were included.