Publications by authors named "Pelin Unsal"

Background: The aim of this study is to determine cutoff values for different appendicular skeletal muscle mass index (ASMI) methods measured by dual-energy x-ray absorptiometry (DXA) in a reference group of the Turkish population.

Methods: Body composition analyses were performed with DXA, and appendicular skeletal muscle mass (ASM) was adjusted to body size as ASMI using height squared (ASM/ht), weight (ASM/wt), and body mass index (BMI) (ASM/BMI). Sex-specific cutoff values were obtained as 1 and 2 standard deviations (SDs) below the mean values of ASM/ht, ASM/wt, and ASM/BMI.

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Purpose: The aim of the study was to compare balance performance in mild-moderate stage Alzheimer's disease (AD) patients and healthy peers using clinical balance tests and computerized posturography.

Methods: We recruited 95 patients and divided them into two groups; 51 patients (62 % (n=32) female) in AD group and 44 patients in healthy controls group (50 % (n=22) female). Berg Balance Scale (BBS) and Timed Up & Go (TUG) test were performed.

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Introduction: Physical phenotype and the cumulative deficit model are two well-known concepts of frailty. One of the main components of frailty is loss of muscle mass and function, which may also include swallowing muscles, therefore is a risk factor for dysphagia. Since dysphagia is seen starting from the early stages of Alzheimer's Disease (AD), in this study we aimed to reveal the relationship between frailty and dysphagia and dysphagia-related quality of life through Swallow Quality of Life (SwalQoL) tool in patients with AD and compare them with cognitively intact older adults.

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Article Synopsis
  • Alzheimer's disease is often associated with nutrition disorders such as malnutrition, frailty, and sarcopenia among older patients, emphasizing the need for comprehensive assessments.
  • In a study of 253 older patients, 64.8% were malnourished or at risk, 38.3% had sarcopenia, and a significant portion was classified as frail, with these issues worsening as Alzheimer's progressed.
  • The study highlights the importance of identifying and managing these nutrition-related conditions in Alzheimer's patients to improve overall health and outcomes.
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  • - The study compared the Mini Nutritional Assessment-Short Form (MNA-SF) and Long Form (MNA-LF) to see which better predicts mortality in geriatric outpatients over 7 years.
  • - Out of 209 patients followed, 36.8% died within the study period, with MNA-SF showing a significant association with mortality across various follow-up periods, though MNA-LF excelled in predicting short-term mortality (6-month and 1-year).
  • - Both assessment tools effectively predict mortality risk, with MNA-SF offering valuable information for identifying patients at risk for malnutrition, emphasizing the need for regular screening in older adults to enable early interventions.
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Objectives: This study aimed to provide data about the role of muscle ultrasound (US) to predict sarcopenia.

Methods: A total of 313 geriatric outpatients (age ≥65 y) were enrolled in the study. After a comprehensive geriatric assessment, anthropometric measurement and handgrip strength (HGS) data were obtained and a bioelectrical impedance analysis was performed.

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Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging also affect swallowing functions and cause presbyphagia. This condition may progress to oropharyngeal and/or esophageal dysphagia in the presence of secondary causes that increase in incidence with aging.

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Background: Sars-CoV-2 infection influences older individuals at the forefront, and there is still limited data on the COVID-19 vaccine response in the geriatric population. This study aimed to assess antibody response after vaccination with SARS-CoV-2 inactivated vaccine and examine possible factors affecting this response in a geriatric population.

Methods: individuals who have been on at least the 28th day after the second dose of the COVID-19 vaccine were included.

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Background: The aim of this study is to identify cutoff values for muscle ultrasound (US) to be used in Global Leadership Initiative on Malnutrition (GLIM) criteria, and to define the effect of reduced muscle mass assessment on malnutrition prevalence at hospital admission.

Methods: A total of 118 inpatients were enrolled in this cross-sectional study. Six different muscles were evaluated by US.

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Background: Endometrial cancer (EC) is most frequently seen in older and postmenopausal women.

Aim: The aim of this study was to evaluate the rate of recurrence and survival and clinical, pathological, surgical, and treatment factors affecting recurrence and survival in older patients with EC.

Methods: Three hundred and six (21.

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Aim: Poor adherence with dementia medications is common among patients and caregivers, owing to the absence of perceived effect, polypharmacy, and adverse effects. The aim of this study was to evaluate the effect of clinical pharmacists' interventions on the adherence to dementia treatment and the caregivers' knowledge of dementia.

Methods: This study was conducted at a geriatric outpatient clinic of the university hospital between October 2018 and April 2019.

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Objectives: Masked hypertension, defined as nonelevated clinic blood pressure with elevated out of clinic blood pressure, has been associated with increased cardiovascular events, mortality and cognitive impairment. No evidence exists regarding the effect of treating masked hypertension. In this study, we followed-up the patients in the G-MASH-cog study for 1 year and aimed to examine the effect of the management of masked hypertension on cognitive functions.

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Background: Insomnia increases the incidence of falls and impairs executive function. Moreover, falls are associated with executive function impairment. The relationship between falls and executive function in patients with insomnia is not clear.

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Background/aim: Gastrointestinal (GI) system cancers are frequent among older adults and it is still difficult to predict which are at increased risk for postoperative complications. Frailty and sarcopenia are increasing problems of older population and may be associated with adverse outcomes. In this study we aimed to examine the effect of sarcopenia and frailty on postoperative complications in older patients undergoing surgery for GI cancers.

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Purpose: Insomnia, a common problem in older adults, may be precipitated by multiple factors including medical conditions, social, behavioral, and environmental factors. The aims of our study were to evaluate sleep pattern changes during hospitalization, determine the predictors of sleep quality and sleep disorders in geriatric inpatients.

Methods: In this prospective observational study, all ≥ 65-year-old patients hospitalized in internal medicine wards were assessed at the time of hospitalization and after 1 week.

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Background And Aim: Mild cognitive impairment (MCI) and dementia prevalence are expected to increase with aging. The DemTect is a very quick and easy tool to administer and recognize the early stages of dementia and MCI. In this study we aimed to evaluate the reliability and validity of a Turkish version of the DemTect and define cut off values for different age and educational levels.

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Background: Sarcopenic obesity (SO) is the coexistence of sarcopenia and obesity in an individual. The present study is designed to define the usefulness of skeletal muscle ultrasonography (US) in the definition of SO.

Methods: Eighty-nine participants aged ≥65 whose body mass index (BMI, kg/m ) was ≥30 were consecutively enrolled in an outpatient clinic of geriatric medicine.

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Article Synopsis
  • Atrial fibrillation (AF) is a common heart condition in older adults that leads to serious health issues like stroke and dementia, and the study aims to explore its link with frailty and overall functionality in this age group.
  • The study involved 123 older patients, split into those with AF and those with normal heart rhythms, who underwent extensive assessments to determine their frailty status and quality of life.
  • Results showed that while frailty was more common in the AF group, the difference wasn't statistically significant, but symptoms of AF were positively correlated with frailty, suggesting that AF could act as a marker for frailty in older adults.
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: Muscle strength seems to be more relevant to the functionality than muscle mass in sarcopenia. Different diagnostic techniques are available for the evaluation of muscle mass. Ultrasonography (USG) seems to have some advantages compared to other techniques especially bioelectrical impedance analysis (BIA) including being not affected of the results by the factors like extreme body mass indexes (BMI) or hypervolemia.

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