Publications by authors named "Pelin Esme"
Objective: The combination of adalimumab and surgical interventions plays a crucial role in managing severe hidradenitis suppurativa (HS). However, there is still limited scientific evidence regarding administering adalimumab during the perioperative period. This study aimed to evaluate whether adalimumab could adversely affect postoperative complications and the total time of wound closure (TTWC) in patients undergoing cutaneous surgery for HS.
View Article and Find Full Text PDFBackground And Objectives: The effect of environmental and genetic factors on the aging process is widely acknowledged. Yet, the extent to which each factor decisively contributes to the perception of looking younger or older remains a subject of debate. This study seeks to identify the factors linked to the perceived age among Turkish women.
View Article and Find Full Text PDFArticle Synopsis
- Genital lymphoedema is a rare and challenging complication linked to longstanding hidradenitis suppurativa (HS), with limited successful treatment options available.
- A case study of a 56-year-old male with severe scrotal lymphoedema due to HS highlights the ineffectiveness of antibiotics and the introduction of ixekizumab alongside complex decongestive therapy (CDT).
- After just six sessions of CDT over two weeks, the patient experienced significant improvements, including reduced swelling, better aesthetics, and easier urination, suggesting CDT's effectiveness for HS-related genital lymphoedema.
Introduction: Biostimulation properties of diluted and hyperdiluted calcium hydroxylapatite (CaHA) injections have become increasingly popular. However, the existing data are insufficient to certify a particular dose-response pattern.
Objective: To assess and compare the dermal stimulation potentials of different concentrations of CaHA injections.
Facial Bier Spots Unresponsive to Botulinum Toxin: A Case Series.
Dermatol Pract Concept
January 2023
Increased Prevalence of Bipolar Disorders in Hidradenitis Suppurativa: More Than a Striking Co-existence?
Dermatol Pract Concept
November 2022
Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder of the hair follicle characterized by intense discharge and pain. Recently, HS intrinsic association with neuropsychiatric disorders has become a focus of attention, and bipolar disorder (BD) emerged as a relevant topic for such an association.
Objectives: This study aimed to evaluate BD prevalence among HS patients and present the HS and BD overlap patients demographics, detailed clinical characteristics with a discussion on aggravating factors.
Article Synopsis
- There is a significant need for effective treatment options for hidradenitis suppurativa (HS), despite existing approved therapies.
- This study evaluated the effectiveness of certolizumab pegol in 11 severe HS patients who had not responded to adalimumab, observing clinical responses after 12 and 24 weeks of treatment.
- Results showed that 54.5% of patients achieved a clinical response at week 12, and there were significant improvements in quality of life and severity scores, suggesting that certolizumab pegol could be a viable treatment for hard-to-treat HS cases.
Article Synopsis
- Adalimumab is currently the only approved biologic treatment for hidradenitis suppurativa (HS), but it may not work for everyone; ixekizumab, an interleukin 17 inhibitor, has shown potential as an alternative.
- A study involving 5 patients with severe HS who were unresponsive to conventional treatments and adalimumab found that 80% achieved a significant treatment response after 12 weeks of ixekizumab.
- Improvements were noted in patients' quality of life, with no reported adverse reactions from ixekizumab, indicating it may be a viable option for difficult HS cases.
Tranexamic acid (TA) emerged as a promising agent for melasma. However, due to its hydrophilic structure, topical TA should be combined with a penetration-enhancing strategy to augment efficacy. To evaluate the efficacy of fractional erbium:YAG laser-assisted delivery (LAD) of topical TA 5% either with or without oral TA treatment in recalcitrant melasma patients.
View Article and Find Full Text PDFNicolau syndrome is a rare serious drug reaction associated with the administering various injectable medications. It is often characterized by an acute and severe pain accompanying erythema that tends to rapidly evolve into the livedoid reticular or hemorrhagic patches and less commonly to ulcers and skin necrosis. Herein, we report a 34-year-old woman who presented with painful, tender discoloration over her abdominal skin following subcutaneous glatiramer acetate injection.
View Article and Find Full Text PDFBackground: The use of medical terms and folk names (euphemisms) affect a patient's understanding of diseases and perceptions of severity.
Objectives: We determine the psychological effects on patients with hidradenitis suppurativa of medical and folk names of their disease.
Methods: This was a cross-sectional and exploratory study conducted at a tertiary referral university hospital in Turkey.
Background: Burnout affects all physicians, including dermatologists. Long working hours, high workload, and work-related activities outside working hours are common risk factors for burnout that disrupt the work-life balance. This study aimed to evaluate dermatologists' approach to online consultation requests via social media (SM) and instant messaging services (IMS), the psychological effects of these consultations on dermatologists, and their relationship with burnout syndrome.
View Article and Find Full Text PDFPsoriasis is a chronic inflammatory skin disease that is characterized by well-demarcated erythematous plaques with a silver scale. Although many new and emerging therapeutic agents are often sufficient to control the disease, there is still a need for alternative treatment options in challenging cases. Extracorporeal photopheresis (ECP) has been applied to many T-cell-mediated diseases to restore immune homeostasis and treat psoriasis effectively.
View Article and Find Full Text PDFRationale, Aims, And Objective: Medical consultations of family physicians play a key role in early diagnosis and proper management of hidradenitis suppurativa (HS). This study aimed to investigate family physicians' disease awareness, general attitudes, and knowledge of HS.
Material-methods: This cross-sectional descriptive study was conducted with 211 family physicians and residents through a web-based survey.
Hidradenitis suppurativa (HS) causes significant psychological distress in patients. We aimed to investigate the stigmatization level of HS patients and to determine the related physical, social, and psychological factors. A questionnaire with 22 questions about the physical and psychosocial problems related to HS was administered to 29 male and 34 female patients between the ages of 18 and 66 to evaluate the thoughts, emotions, attitudes, and behaviors of patients.
View Article and Find Full Text PDFRapid Response to Certolizumab Pegol in Hidradenitis Suppurativa: A Case Report.
Skin Appendage Disord
January 2021
Article Synopsis
- * A 43-year-old male patient with HS experienced varying responses to multiple treatments over 15 years, eventually showing improvement with certolizumab pegol after other therapies failed or worsened his condition.
- * Certolizumab pegol, primarily approved for plaque psoriasis, shows promise as a potential effective treatment for HS, especially in tough cases, highlighting the need for further exploration in its use for this condition.
Background: Breakages of the cold chain of botulinum neurotoxin A (BONT-A) preparations is not a rare event and occurs due to several unexpected and unintentional reasons during daily practice and intervention schedules could not be proposed due to the lack of data.
Objective: To investigate the heat stability of abobotulinum toxin A (AboBONT-A) in terms of efficacy and duration of action upon storage at room temperature (25°C) for 2, 4, and 8 weeks.
Methods And Materials: Twenty rabbits were divided into four groups and received an injection of ideally stored AboBONT-A (Group 1) and stored AboBONT-A for 2 (Group 2), 4 (Group 3), and 8 weeks (Group 4) at room temperature into the anterior auricular muscle.
Background: Coronavirus 2019 (COVID-19) disease has rapidly spread worldwide with a multitude effects on daily life. Since the transmission risk increases with close contact, some cosmetic procedures are considered high risk and majority of them had to be postponed or canceled in private dermatocosmetology clinics especially during the heavy period of the outbreak.
Aims: We aimed to document the medical and socioeconomic problems emerged in dermatocosmetology clinics in Turkey caused by COVID-19 pandemic and to discuss the management strategies taken by dermatologists.
Background: Narrow-band ultraviolet B (nb-UVB) phototherapy constitutes the gold standard treatment for vitiligo. Whether carbon dioxide (CO2) laser might increase the efficacy of nb-UVB is still a topic of debate.
Objective: To test the hypothesis that the addition of fractional CO2 laser to nb-UVB may enhance repigmentation.