Tc-Sestamibi/I Subtraction SPECT/CT in Parathyroid Scintigraphy: Is Additional Pinhole Imaging Useful?

Objectives: This retrospective study evaluated whether the use of additional anterior Tc-sestamibi/I pinhole imaging improves the outcome of Tc-sestamibi/I subtraction SPECT/CT in parathyroid scintigraphy (PS).

Materials And Methods: PS using simultaneous dual-isotope subtraction methods and an acquisition protocol combining SPECT/CT and planar pinhole imaging was performed for 175 patients with primary or secondary hyperparathyroidism. All patients who proceeded to surgery with complete postsurgery laboratory findings were included in this study ( = 94).

Comparison of five parathyroid scintigraphic protocols.

Objectives. We compared five parathyroid scintigraphy protocols in patients with primary (pHPT) and secondary hyperparathyroidism (sHPT) and studied the interobserver agreement. The dual-tracer method ((99m)Tc-sestamibi/(123)I) was used with three acquisition techniques (parallel-hole planar, pinhole planar, and SPECT/CT).