Vapor deposition assisted in-situ construction of graphitic carbon nitride homojunction capable of enhanced visible-light-driven hydrogen generation.

Graphitic carbon nitride (g-C3N4) has garnered considerable attention in the field of photocatalysis due to its suitable bandgap (~2.7 eV), abundant elemental composition, high chemical stability, and environmentally friendly synthesis process. In this study, a novel g-C3N4 homojunction material with controllable morphology was successfully fabricated via a simple and efficient vapor deposition method.

Isolation and identification of two novel PDE-5 inhibitors illegally added to pressed candies.

Two novel phosphodiesterase 5 (PDE-5) inhibitors were detected in pressed candy using high-performance liquid chromatography (HPLC)-diode array detection. Following extraction with acetonitrile and sonication, the compounds were isolated and purified semi-preparative liquid chromatography. Structural characterisation was achieved through high-resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR) spectroscopy.

Isolation and characterisation of N-benzyl tadalafil as a novel adulterant in a coffee-based dietary supplement.

A new tadalafil analogue was detected via high-performance liquid chromatography (HPLC)-diode array detection (DAD) during routine screening of health foods suspected of adulteration with erectile dysfunction drugs. The UV absorption spectrum of the unknown was almost identical to that of tadalafil. The analogue was purified by preparative HPLC and structural elucidation carried out by mass spectrometric and NMR spectroscopic experiments.

[Application of quantitative evaluation on multicomponent drug interaction in anti-HIV research].

Objective: To quantitatively evaluate mutual relations of 4 component drugs in anti-HIV action.

Methods: The effect of TCM four components on cell growth was detected using MTT assay. The antiviral effects of 4 components were observed at the maximal nonvenomous dose.

[Using parallel line assay method based on quantitative responses in methodology evaluation for determining lumbrokinase potency in Rongshuan capsules].

Objective: To develop an assay methodology for determination of lumbrukinase potency in Rongshuan capsules.

Method: The agarose-fibrin plate assay methodology for determination of Lumbrukinase potency in Rongshuan capsules was studied including durability, specificity, linearity range, product's handling method, accuracy , repetitiveness, solution stability, recovery and statistical method. The method of parallel line assay based on quantitative responses in statistical methods for biological assays was used in the statistics of potency assay.