Effect of acupuncture combined with auricular beanembedding on autonomic nervous system function, heart rate variability and mental state of migraine patients.

Objective: To analyze the effects of acupuncture combined with auricular bean embedding on autonomic nervous dysfunction, heart rate variability and psychological state of migraine patients.

Method: Sixty migraine patients admitted to our hospital from August 2022 to June 2023 were selected for this retrospective study. Based on their treatment protocols, the patients were divided into the acupuncture alone group (control group) and acupuncture combined with auricular bean embedding group (observation group), with 30 cases in each group.

Electroacupuncture extends the time window of thrombolytic therapy in rats by reducing disruptions of blood-brain barrier and inhibiting GSDMD-mediated pyroptosis.

Objective: Thrombolytic therapy is the primary treatment for acute ischemic stroke. Extending the therapeutic time window can effectively reduce the harmful side effects associated with thrombolytic therapy. Although electroacupuncture (EA) has been shown to extend this time window, the specific mechanisms remain unclear.

The factors associated with the caregiving burden among family caregivers of pediatric patients with fractures: A descriptive cross-sectional study.

Purpose: To investigate the factors linked to the caregiving burden among family caregivers of pediatric patients with fractures.

Methods: This descriptive cross-sectional research used non-probabilistic sampling involving 200 pediatric patients (0-14 years) with fractures and their family caregivers. Data was collected between November 2019 and June 2020.

Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.

Objective: To explore the effect of acupuncture treatment on cerebral ischaemia-reperfusion injury (CIRI) and reveal the underlying mechanism of the effect based on nuclear receptor coactivator 4 (NCOA4) mediated ferritinophagy.

Methods: Sprague-Dawley male rats were divided into four groups: the sham group, model group, acupuncture group, and sham acupuncture group. After 2 h of middle cerebral artery occlusion (MCAO), reperfusion was performed for 24 h to induce CIRI.

[Effect of acupuncture on HIF-1α/NLRP3 inflammatory signaling pathway in the rats with cerebral ischemia-reperfusion injury].

Objective: To observe the effects of (regaining consciousness and opening orifices) acupuncture therapy on the expression of hypoxia-inducible factor 1α (HIF-1α) and Nod-like receptor protein 3 (NLRP3) in cerebral ischemia-reperfusion rats, and to explore the mechanism of acupuncture against cerebral ischemia-reperfusion injury.

Methods: Seventy-two male SD rats were randomly divided into a sham-operation group, a model group, an acupuncture group and a non-point acupuncture group, with 18 rats in each one. Using modified Longa thread embolization method, the rat model of acute focal cerebral ischemia was prepared; and after 2 h ischemia, the reperfusion was performed to prepared the model of cerebral ischemia-reperfusion.

The efficacy and safety of acupuncture therapy for sciatica: A systematic review and meta-analysis of randomized controlled trails.

Background And Objective: Sciatica is a common type of neuropathic pain disease which poses a huge financial burden to the patient. For patients with sciatica, acupuncture has been recommended as an effective method for pain relief, while there is currently a lack of sufficient evidence to support its efficacy and safety. In this review, we aimed to critically assess the published clinical evidence on the efficacy and safety of acupuncture therapy for treating sciatica.

miR-219a-5p inhibits the pyroptosis in knee osteoarthritis by inactivating the NLRP3 signaling via targeting FBXO3.

Purpose: This work was to identify the function and mechanism of miR-219a-5p in regulating knee osteoarthritis (KOA).

Methods: Rat fibroblast-like synoviocytes (FLSs) were isolated to construct KOA cell model by lipopolysaccharide and adenosine triphosphate treatment. miR-219a-5p and FBXO3 expression in FLSs was modulated by transfection.

Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis.

Background: Osteoarthritis (OA) is a chronic degenerative joint disease and the most frequent type of arthritis. This study aimed to identify the key miRNAs and genes associated with OA progression.

Methods: The GSE105027 (microRNA [miRNA/miR] expression profile; 12 OA samples and 12 normal samples) and GSE48556 (messenger RNA [mRNA] expression profile; 106 OA samples and 33 normal samples) datasets were selected from the Gene Expression Omnibus database.

Flexural Performance of Sisal Fiber Reinforced Foamed Concrete under Static and Fatigue Loading.

To improve the weak mechanical properties of the foamed concrete that resulted from a large number of pores, a plant fiber is used as fill with the matrix. In this study, five contents of sisal fiber are added into the foamed concrete to investigate the static and fatigue performance of composites. The static and fatigue experimental results show that the sisal fiber can improve the mechanical properties of the foamed concrete.

Effect of Subtropical Natural Exposure on the Bond Behavior of FRP-Concrete Interface.

Subtropical natural exposure may significantly affect the bonding behavior of fiber reinforced polymer (FRP) externally bonded to concrete. To study the effect of subtropical natural climates on the FRP-concrete interface, natural exposure tests and an analytical approach were carried out on specimens externally bonded with carbon fiber reinforced polymer (CFRP) and basalt fiber reinforced polymer (BFRP). The bilinear bond stress-slip relationships for different exposure periods were derived from the experimental results of the strengthened reinforced concrete (RC) beams.

[Corrigendum] Microarray analysis of the molecular mechanisms associated with age and body mass index in human meniscal injury.

Subsequently to the publication of the article, the authors have realized that the grant number in their paper in the Funding section was presented incorrectly: "2017MH77" should have been written as "2017MHZ77". Therefore, the funding information in the declarations section should have appeared as follows: "The present study was funded by the Minhang District Natural Science Project (grant no. 2017MHZ77)".

Sulfate Resistance of Recycled Aggregate Concrete with GGBS and Fly Ash-Based Geopolymer.

There is a constant drive for the development of ultra-high-performance concrete using modern green engineering technologies. These concretes have to exhibit enhanced durability and incorporate energy-saving and environment-friendly functions. The object of this work was to develop a green concrete with an improved sulfate resistance.

Fatigue Life Prediction of Reinforced Concrete Beams Strengthened with CFRP: Study Based on an Accumulative Damage Model.

With the prestressed carbon fiber reinforced polymer (CFRP) strengthening technique widely used in reinforced concrete (RC) structures, it is more and more important to study the fatigue performance of RC structures. Since the fracture of a tensile steel bar at the main cracked section is the leading reason for the failure of RC beams reinforced by prestressed CFRP, a fatigue life prediction model of RC beams reinforced by prestressed CFRP was developed based on an accumulative damage model. Moreover, gradual degradation of the performance of the concrete was considered in the fatigue life prediction model.

Microarray analysis of the molecular mechanisms associated with age and body mass index in human meniscal injury.

The aim of the present study was to identify genes and functional pathways associated with meniscal injuries affected by age or body mass index (BMI) using microarray analysis. The GSE45233 gene expression dataset with 12 injured meniscus samples associated with age and BMI and GSE66635 dataset with 12 injured and 12 normal meniscus samples were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were identified based on age or BMI in GSE45233.

Fatigue Performance of RC Beams Strengthened with CFRP under Overloads with a Ladder Spectrum.

Vehicle overload is detrimental to bridges and traffic safety. This paper presents a study on the fatigue performance of typical reinforced concrete (RC) beams of highway bridges under vehicle overload. A definition method of vehicle overload and a construction method of overload ladder spectrum were first proposed based on traffic data acquisition, statistical analysis and structural calculation of the highway bridges in Guangzhou.

[Preliminary effectiveness of I.T.S. locking plate for intra-articular calcaneal fractures].

Objective: To summarize the preliminary effectiveness of I.T.S.

Specialization of mitochondrial and vascular oxidant modulated VEGFR in the denervated skeletal muscle.

Denervation of skeletal muscles results in timely muscular inflammation and muscle-T cell interaction, the cellular events might orchestrate a local circuit involved with IL-1β and IL-15. In the present study, by a combination assay of nerve-muscle preparation, western blot, immuno-precipitation, and radioactive of enzyme activity, we confirmed that mitochondrial and vascular oxidants were considerably up-regulated following gastrocnemius denervation, which was due to gradual decay in mitochondrial biogenesis and XO pathway and accompanied by strengthened IL-1β-VEGFR-2 and IL-15-VEGFR-1 signaling. Intriguingly, these alterations could be triggered by the early established muscular inflammation.

[Treatment of mid-distal humeral shaft fractures associated with radial nerve palsy using minimally invasive plating osteosynthesis technique].

Objective: To explore the possibility of treating mid-distal humeral shaft fractures associated with radial nerve palsies with minimal invasive plating osteosynthesis (MIPO) techniques.

Methods: From April 2003 to October 2006, 10 patients with mid-distal humeral shaft fractures associated with radial nerve palsies were treated. All patients were male, aged 19-58 years.

Minimally invasive plating osteosynthesis (MIPO) of middle and distal third humeral shaft fractures.

Objective: To evaluate the clinical, radiographic, and functional outcomes of middle and distal third humeral shaft fractures treated with the minimally invasive percutaneous osteosynthesis (MIPO).

Design: Prospective, single-center, nonconsecutive clinical series study.

Setting: : Skeletal trauma center of a university teaching hospital.