Terahertz spectroscopic characterizations and DFT calculations of indomethacin cocrystals with nicotinamide and saccharin.

Co-crystallization is an effective strategy to improve the drug properties such as solubility and stability. However, its thermodynamic backgrounds, especially lattice vibration, haven't been fully understood. In this work, indomethacin (IND) cocrystals formed with nicotinamide (NIC) and saccharin (SAC) are successfully characterized by using terahertz spectroscopy.

[Effect of lactic acid bacteria isolated from Tibetan Plateau on silage fermentation quality of Elms nutans].

Objective: In order to detect the effect of lactic acid bacteria isolated from Tibetan Plateau on silage fermentation quality of Elms nutans.

Methods: We used 3 isolated lactic acid bacteria with better growth at low temperatures of 10 and 15 degrees C at ensiling of Elymus nutans. Subsequently, effects of the selected lactic acid bacteria on fermentation profiles of Elymus nutans silages stored at 15 and 25 degrees C were evaluated by using the same species of commercial inoculants as the control.