During an ERCP procedure for bile duct stones, the patient experienced basket impaction during the operation. We successfully removed the impacted reticular basket without complications, utilizing a temporary salvage device modified with a lithotripter, thereby avoiding other future procedures such as ESWL or surgery.
View Article and Find Full Text PDFPhotonic integrated quantum memories are essential for the construction of scalable quantum networks. Spin-wave quantum storage, which can support on-demand retrieval with a long lifetime, is indispensable for practical applications, but has never been demonstrated in an integrated solid-state device. Here, we demonstrate spin-wave quantum storage based on a laser-written waveguide fabricated in a Eu:YSiO crystal, using both the atomic frequency comb and noiseless photon-echo protocols.
View Article and Find Full Text PDFThree novel coordination polymers (CPs), namely [Cu(μ-1κO,2κN-L)] (1), [Zn (μ-1κO,2κN-L)(HO)] (2) and [Cd (μ-1κOO',2κN-L)] (3) [where HL = 4-(pyrimidin-5-ylcarbamoyl)benzoic acid], were synthesized and characterized by elemental analysis, ATR-IR, TGA, XPS and single-crystal X-ray diffraction. Despite having the same organic ligand, the various metal cations had an impact in the subsequent frameworks. Hirshfeld surface analysis was performed to investigate the intermolecular interactions and to examine the stability of the crystal structures of the three polymers.
View Article and Find Full Text PDFTwo new porous three-dimensional cadmium(II) metal-organic frameworks (MOFs) containing thiophene-appended carboxylate acid ligands, formulated as [Cd(L1)(4,4'-Bipy)].2(DMF) () and [Cd(L2)(4,4'-Bipy)].2(DMF) () [where L1 = 5-{(thiophen-2-ylmethyl)amino}isophthalate, L2 = 5-{(thiophen-3-ylmethyl)amino}isophthalate, 4,4'-Bipy = 4,4'-bipyridine, and DMF = ,'-dimethylformamide] have been synthesized and structurally characterized.
View Article and Find Full Text PDFBackground: Surgical risk assessment is intriguing for clinical decision-making of brainstem cavernous malformation (BSCM) treatment. While the BSCM grading scale, encompassing size, developmental venous anomaly, crossing axial midpoint, age, and timing of intervention, is increasingly utilized, the clinical relevance of neurological fluctuation and recurrent hemorrhage has not been incorporated. This study aimed to propose a supplementary grading scale with enhanced predictive efficacy.
View Article and Find Full Text PDFObjective: Craniocervical junction arteriovenous fistulas (CCJ-AVFs) are complex vascular shunts that present a challenge for treatment. The aim of this study was to compare the clinical outcomes of microsurgery and endovascular embolization for CCJ-AVFs and to determine whether the treatment approach affected the obliteration rate and neurological improvement.
Methods: The authors conducted a retrospective analysis of 64 patients who had undergone microsurgery or endovascular embolization for CCJ-AVF at one of two neurosurgical centers from January 2014 to February 2022.
RNA modification, especially RNA methylation, is a critical posttranscriptional process influencing cellular functions and disease progression, accounting for over 60% of all RNA modifications. It plays a significant role in RNA metabolism, affecting RNA processing, stability, and translation, thereby modulating gene expression and cell functions essential for proliferation, survival, and metastasis. Increasing studies have revealed the disruption in RNA metabolism mediated by RNA methylation has been implicated in various aspects of cancer progression, particularly in metabolic reprogramming and immunity.
View Article and Find Full Text PDFBackground: Brainstem cavernous malformations (BSCMs) often present with haemorrhage, but the optimal timing for microsurgical intervention remains unclear. This study aims to explore how intervention timing relates to neurological outcomes in haemorrhagic BSCM patients undergoing microsurgery, offering insights for clinical decisions.
Methods: A total of 293 consecutive patients diagnosed with BSCMs, who underwent microsurgery were identified between March 2011 and January 2023 at two comprehensive centres in China, with a postoperative follow-up duration exceeding 6 months.
Background: Due to their crucial functional location, surgical treatment of brainstem arteriovenous malformations (AVMs) has always been challenging. For unruptured AVMs, we can determine whether radiological therapy, interventional treatment, or surgical resection is feasible based on the AVM structure. However, for ruptured AVMs, microsurgical resection and interventional embolization are effective methods to prevent further rupture.
View Article and Find Full Text PDFBackground: Middle cerebral artery (MCA) M1 bifurcation aneurysms are common because of hemodynamic. For regular-shaped and small aneurysms, direct clipping is optimal. Aneurysmoraphy or bypass blood flow reconstruction are most commonly used in large aneurysm clipping.
View Article and Find Full Text PDFDual-lumen angioplasty balloon microcatheters make it possible to perform percutaneous transluminal angioplasty (PTA), low-profile stent delivery, and intrastent dilation without the microcatheter exchange technique. This technique has shown many advantages in recent years. We reviewed the techniques and applications in different intracranial vascular diseases and summarized the outcomes and indications.
View Article and Find Full Text PDFDifferent Cr-based bimetallic oxides were prepared, and their catalytic performance was evaluated on the simultaneous removal of multi-VOCs mixtures (acetone, benzene, toluene, and o-xylene) by ozonation. Among them, Co-Cr catalyst stood out in catalytic ozonation of aromatic VOCs, and its activity on acetone conversion was promoted by raising the temperature and ozone concentrations, owing to lower crystallization, larger surface area, excellent redox and VOCs/CO desorption ability. Above 95% conversion of all multi-VOCs was achieved over the Co-Cr catalyst when the temperature was 100 °C and an excess ozone ratio λ (the ratio of actual moles of ozone to theoretical moles of ozone needed) was equal to 3.
View Article and Find Full Text PDFArteriovenous fistulas (AVFs) at the craniocervical junction (CCJ) are uncommon conditions with complex angioarchitecture. The objective of this study was to identify the angioarchitectural features of CCJ-AVF that were predictive of clinical presentation and neurological function. The study encompassed a total of 68 consecutive patients with CCJ-AVF at two neurosurgical centers between 2014 and 2022.
View Article and Find Full Text PDFObjective: Complex anterior cerebral artery (ACA) aneurysms are still technically challenging to treat. Bypass surgery is needed to achieve aneurysm obliteration and ACA territory revascularization. Severe atherosclerosis of aneurysm walls can cause clip slippage, intraoperative rupture, postoperative ischemic events.
View Article and Find Full Text PDFBACKGROUND : Selective biliary cannulation is the most challenging step in endoscopic retrograde cholangiopancreatography (ERCP) because only indirect radiographic images can be obtained. Therefore, we developed a novel endoscopic retrograde direct cholangioscopy (ERDC) technology to facilitate visible biliary cannulation. METHODS : In this case series, we used ERDC to treat 21 patients with common bile duct stones who were enrolled consecutively between July 2022 and December 2022.
View Article and Find Full Text PDFBackground: The bypass technique is important for treating complex intracranial aneurysms and is infrequently performed. Intracranial-intracranial (IC-IC) bypass has shown many advantages in recent years.
Objective: To review the techniques and outcomes of bypass based on anterior cerebral artery (ACA) A1 donor anastomosis in patients with intracranial aneurysm.
Gastroenterol Rep (Oxf)
January 2023
Background: In colonoscopy screening for colorectal cancer, human vision limitations may lead to higher miss rate of lesions; artificial intelligence (AI) assistance has been demonstrated to improve polyp detection. However, there still lacks direct evidence to demonstrate whether AI is superior to trainees or experienced nurses as a second observer to increase adenoma detection during colonoscopy. In this study, we aimed to compare the effectiveness of assistance from AI and human observer during colonoscopy.
View Article and Find Full Text PDFBackground: MR vascular wall imaging (VWI) may have prognostic value in patients with unruptured intracranial aneurysms (UIAs).
Objective: To evaluate the value of VWI as a predictor of surgical outcome in patients with UIAs.
Methods: This prospective cohort study evaluated surgical outcomes in consecutive patients with UIAs who underwent surgical clipping at a single center.
Background: Middle cerebral artery (MCA) M1 aneurysms with M2 branches originating from the aneurysm neck are difficult to treat because of blood flow reconstruction method selection, graft blood volume matching and various anastomoses.
Method: We report a case of MCA M1 bifurcation aneurysm resection and reconstruction of the bifurcation using "Y" fashion anastomosis. Intraoperative DSA showed anastomotic stoma patency.
Objective: Brainstem cavernous malformations (BSCMs) represent a unique subgroup of cavernous malformations with more hemorrhagic presentation and technical challenges. This study aimed to provide individualized assessment of the rehemorrhage clustering risk of BSCMs after the first symptomatic hemorrhage and to identify patients at higher risk of neurological deterioration after new hemorrhage, which would help in clinical decision-making.
Methods: A total of 123 consecutive BSCM patients with symptomatic hemorrhage were identified between 2015 and 2022, with untreated follow-up > 12 months or subsequent hemorrhage during the untreated follow-up.
Background: Dural arteriovenous fistulas (DAVF) represent almost 10-15% of intracranial malformations that cause intracranial hemorrhage and focal neurological deficits. Seldom tentorial DAVF cases present with ocular manifestations initially, which occur frequently in carotid-cavernous fistula (CCF) and cavernous sinus DAVF (CS DAVF).
Case Presentation: We report an unusual falcotentorial DAVF case draining via the superior and inferior ophthalmic veins that caused left-side increased intraocular pressure.
Background: Optimal treatment of patients with high Spetzler-Martin (S-M) grade brain arteriovenous malformations (BAVMs) remains controversial. Few studies have investigated outcomes in such patients treated in a hybrid operating room (hOR).
Objective: To examine outcomes of one-stop hybrid BAVM treatment in patients with high-grade lesions.
Five Mn-loaded catalysts were synthesized on γ-AlO, TiO, ZrO, nano γ-AlO and nanoZrO supports. The catalytic ozonation of DCM (dichloromethane) was evaluated under industrial conditions (, temperature, O input, HO and SO content). According to results, >90% DCM conversion without O residue was achieved for all samples at 120 °C and an O/DCM ratio of 6.
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