An investigation of segmentation methods and texture analysis applied to tomographic images of human vertebral cancellous bone.

The goal of this study is to determine architectural and textural parameters on computed tomographic (CT) images, allowing us to explain the mechanical compressive properties of bone. Although the resolution (150 microm) is of the same order of magnitude as the trabecular thickness, this method enables the possibility of perfecting an in vivo peripheral CT system with an acceptable radiation dose for the patient. This study was performed on L2 vertebrae cancellous bone specimens taken after necropsy in 22 subjects aged 47-95 years (mean: 79 years).

High-resolution computed tomography for architectural characterization of human lumbar cancellous bone: relationships with histomorphometry and biomechanics.

The aim of the present study on human vertebral cancellous bone was to validate structural parameters measured with high-resolution (150 microm) computed tomography (HRCT) by referring to histomorphometry and to try to predict mechanical properties of bone using HRCT. Two adjacent vertical cores were removed from the central part of human L2 vertebral body taken after necropsy in 22 subjects aged 47-95 years (10 women, 12 men; mean age 79 +/- 14 years). The right core was used for structural analysis performed by both HRCT and histomorphometry.

Mechanical properties of ewe vertebral cancellous bone compared with histomorphometry and high-resolution computed tomography parameters.

The goal of the present study was to determine if a high-resolution computed tomography (HRCT) system with 150 microns resolution was sufficient to predict mechanical properties in ewe lumbar vertebrae. To answer this question, we used a triangular comparison between: HRCT; biomechanics (compression and shear tests); and histomorphometry, which was the reference method for the measurements of morphometric parameters. Two dissected lumbar vertebrae (L-4 and L-5) from 32 ewes were used.

A comparison of the ball, wire, edge, and bar/space pattern techniques for modulation transfer function measurements of linear x-ray detectors.

Actual assessment of the modulation transfer function (MTF) of a physical system requires objective experimental data to be obtained. This paper presents four practical methods for measuring the MTF of a linear x-ray detector. These methods are based on using the ball, wire, edge, and bar/space pattern as stimuli.

High-resolution x-ray computed tomography using a solid-state linear detector.

In this paper we present an original low cost acquisition system for computed tomographic imaging. On the first hand, the use of a linear detector consisting of sensitive elements 0.225 mm × 0.

Modulation transfer function evaluation of linear solid-state x-ray-sensitive detectors using edge techniques.

The exact determination of the modulation transfer function (MTF) of a physical system is a persistent problem. We present a practical method of measuring numerically the MTF of linear solid-state x-ray-sensitive detectors. The method is based on the use of edge techniques and allows us to obtain the MTF of a linear detector from its edge-spread function (ESF).

3D display of high resolution vertebral structure images.

In this paper we present a methodology for three-dimensional representation of vertebral structures. A set of X-ray CT images is obtained on a specific high resolution acquisition system. The images are then segmented in order to separate trabecular and cortical structures.

3D display of high resolution vertebral structure images.

A methodology for three-dimensional (3D) representation of vertebral trabecular structures was proposed. A set of X-ray CT images was obtained using a specific high resolution acquisition system. The images were then segmented in order to separate trabecular and cortical bone structures.