Publications by authors named "Peiwen Dong"
Background: Growing evidence suggests that depression affects gastroesophageal reflux disease (GERD). But, the relationship between depression and GERD is unclear. To examine the relationship between depression and the risk of GERD, as well as the mediating role of risk factors.
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- * Findings showed significant relationships: anxiety and depression levels correlated positively with GERD severity, especially among males and influenced by age and literacy.
- * Higher anxiety and moderate to severe depression were linked to greater GERD incidence, with stated odds ratios suggesting a substantial risk increase for individuals with these mental health issues.
Association studies of variations in the 5-hydroxytryptamine (5-HT, serotonin) transporter gene-linked polymorphic region (5-HTTLPR) and functional dyspepsia (FD) have yielded contradictory results. Hence, we performed a meta-analysis to clarify inconsistencies between the 5-HTTLPR polymorphism with FD and it subtypes. We performed a literature search in PubMed, Embase, Web of Science, Cochrane Library, and CNKI, including articles published until March 2022.
View Article and Find Full Text PDFObjective: To investigate the risk factors for pathological upgrading after endoscopic treatment of esophageal lesions which confirmed to be low-grade intraepithelial neoplasia (LGIN) by preoperative biopsy.
Methods: A total of 148 patients who were confirmed to be LGIN in preoperative forceps underwent further endoscopic resection between November 2013 and July 2018. According to the final pathological results after endoscopic treatment, they were divided into pathological upgrading group and pathological non-upgrading group, and their clinicopathological characteristics were analyzed and compared through univariate and multivariate analysis.
[Endoscopic Characteristics and Pathological Analysis of Esophageal Low-grade Intraepithelial Neoplasm].
Sichuan Da Xue Xue Bao Yi Xue Ban
November 2018
Article Synopsis
- The study investigates the characteristics and risk factors associated with low-grade intraepithelial neoplasm (LGIN) in the esophagus by analyzing 201 lesions from 169 patients over an eight-year period.
- Key findings reveal that LGIN is more prevalent in older male patients, with common lesions found in the middle esophagus and specific morphological types being dominant. After monitoring over 10 months, many lesions showed signs of reversal, though some progressed to more severe forms.
- The analysis identified age over 45 and larger lesion size (greater than 0.5 cm) as significant risk factors for developing LGIN, emphasizing the need for careful follow-up in patients with larger lesions.