Publications by authors named "Peitgen H"

Objective: The venous vascular anatomy of the caudate lobe is exceptional. The purpose of this study was to assess portal inflow and venous outflow volumes of the caudate lobe.

Methods: Extrahepatic (provided by the first-order branches) versus intrahepatic (provided by the second- to third-order branches) portal inflow, as well as direct (via Spieghel veins) versus indirect (via hepatic veins) venous drainage patterns were analyzed in virtual 3-D liver maps in 140 potential live liver donors.

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Studies have demonstrated the feasibility of late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging for guiding the management of patients with sequelae to myocardial infarction, such as ventricular tachycardia and heart failure. Clinical implementation of these developments necessitates a reproducible and reliable segmentation of the infarcted regions. It is challenging to compare new algorithms for infarct segmentation in the left ventricle (LV) with existing algorithms.

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Aim: To investigate middle hepatic vein (MHV) management in adult living donor liver transplantation and safer remnant volumes (RV).

Methods: There were 59 grafts with and 12 grafts without MHV (including 4 with MHV-5/8 reconstructions). All donors underwent our five-step protocol evaluation containing a preoperative protocol liver biopsy Congestive vs non-congestive RV, remnant-volume-body-weight ratios (RVBWR) and postoperative outcomes were evaluated in 71 right graft living donors.

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Rationale And Objectives: Accuracy of radiologic assessment may have a crucial impact on clinical studies and therapeutic decisions. We compared the variability of a central radiologic assessment (RECIST) and computer-aided volume-based assessment of lung lesions in patients with metastatic renal cell carcinoma (RCC).

Materials And Methods: The investigation was prospectively planned as a substudy of a clinical randomized phase IIB therapeutic trial in patients with RCC.

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Background: Late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can be used to visualise regions of fibrosis and scarring in the left atrium (LA) myocardium. This can be important for treatment stratification of patients with atrial fibrillation (AF) and for assessment of treatment after radio frequency catheter ablation (RFCA). In this paper we present a standardised evaluation benchmarking framework for algorithms segmenting fibrosis and scar from LGE CMR images.

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The vascular anatomy of the liver can be described at three different levels of complexity according to the use that the description has to serve. The first--conventional--level corresponds to the traditional 8-segments scheme of Couinaud and serves as a common language between clinicians from different specialties to describe the location of focal hepatic lesions. The second--surgical--level, to be applied to anatomical liver resections and transplantations, takes into account the real branching of the major portal pedicles and of the hepatic veins.

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Article Synopsis
  • Computed tomography (CT) is essential for diagnosing lung cancer and the accurate visualization of pulmonary segments has become increasingly important for sublobar lung interventions.
  • The authors introduce an interactive method for segmenting lung areas using the Euclidean distance from the pulmonary artery, with detailed manual segmentations improving accuracy on 11 clinical CT scans.
  • Results indicate that the pulmonary artery-based method achieves segment boundaries with 2-3 mm accuracy and performs significantly better than bronchial tree-based methods, suggesting its potential use in surgical planning for lung resections.
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In this paper we present a benchmarking framework for the validation of cardiac motion analysis algorithms. The reported methods are the response to an open challenge that was issued to the medical imaging community through a MICCAI workshop. The database included magnetic resonance (MR) and 3D ultrasound (3DUS) datasets from a dynamic phantom and 15 healthy volunteers.

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Purpose: To evaluate the significance of the hypertrophy concept in patients requiring extended liver resections for colorectal metastasis in the time of computer assisted surgery.

Methods: Retrospective analysis of patient collective undergoing major liver surgery. 2D CT, 3D CAS with Fraunhofer MeVis Sofware.

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Background: Preoperative imaging and donor selection are cardinal components of adult-to-adult live donor liver transplantation (ALDLT). The purpose of this study was to evaluate our three-dimensional (3D) computed tomography image-derived computer-assisted surgical planning (3D CASP) in ALDLT.

Methods: Eighty-three consecutive ALDLTs (71 right and 12 left) were planned with 3D CASP.

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Background: In adult live donor liver transplantation, postoperative venous congestion of graft and remnant livers can lead to life-threatening complications. The purpose of this study was to evaluate the safety and benefits of our 3-dimensional, computed tomographic, computer-assisted donor hepatectomy using the "carving" partitioning technique.

Methods: Eighty-three consecutive adult live donor liver transplantations were performed based on data obtained from individualized preoperative 3-dimensional, computed tomographic reconstructions and virtual graft hepatectomies.

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Objectives: In chemotherapy monitoring, an estimation of the change in tumour size is an important criterion for the assessment of treatment success. This requires a comparison between corresponding lesions in the baseline and follow-up computed tomography (CT) examinations. We evaluate the clinical benefits of an automatic lesion tracking tool that identifies the target lesions in the follow-up CT study and pre-computes the lesion volumes.

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Purposes: Local resection for hepatocellular carcinoma (HCC) has been traditionally performed non-anatomically. The purpose of this study is to evaluate the feasibility of precise local resection of HCC according to the anatomy of tumor-surrounding vessels revealed by three-dimensional (3D) analysis technique.

Methods: The CT datasets of the livers of the patients with HCC were analyzed three-dimensionally.

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The passage through the hilar plate during right graft live donor liver transplantation (LDLT) can have dangerous consequences for both donors and recipients. The purpose of our study was to delineate hilar transection and biliary reconstruction strategies in right graft LDLT, with special consideration of central and peripheral hilar anatomical variants. A total of 71 consecutive donors underwent preoperative three-dimensional (3D) CT reconstructions and virtual 3D hepatectomies.

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This paper presents image-guided therapies development and advantages using real time imaging modalities such as computed tomography, ultrasound imaging, and magnetic resonance imaging. The following are also highlighted: image-guided cancer interventions and image-guided cardiovascular interventions.

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Phase-Contrast (PC) MRI utilizes signal phase shifts resulting from moving spins to measure tissue motion and blood flow. Time-resolved 4D vector fields representing the motion or flow can be derived from the acquired PC MRI images. In cardiovascular PC MRI applications, visualization techniques such as vector glyphs, streamlines, and particle traces are commonly employed for depicting the blood flow.

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Purpose: Percutaneous image-guided interventions, such as radiofrequency ablation or biopsy, are using needle-shaped instruments which have to be inserted into a target area without penetrating any vital structure. The established planning workflow is based on viewing 2D slices of a pre-interventional CT or MR scan. However, access paths not parallel to the axial plane are often necessary.

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Purpose: Hypodense liver lesions are commonly detected in CT, so their segmentation and characterization are essential for diagnosis and treatment. Methods for automatic detection and segmentation of liver lesions were developed to support this task.

Methods: The detection algorithm uses an object-based image analysis approach, allowing for effectively integrating domain knowledge and reasoning processes into the detection logic.

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Development and integration of image registration methods become increasingly important for clinical workstations. Due to the complexity of such methods, prototyping, evaluation and workflow integration require in-depth knowledge foremostly available to registration developers. Rapid development and deployment is therefore often difficult, particularly for comprehensive software frameworks.

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Purpose: In situ ablation is increasingly being used for the treatment of liver malignancies. The application of these techniques is limited by the lack of a precise prediction of the destruction volume. This holds especially true in anatomically difficult situations, such as metastases in the vicinity of larger liver vessels.

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Purpose: To investigate the feasibility of image fusion of MR-coronary angiography (MRCA) and delayed gadolinium enhancement imaging (LGE) and to assign areas of myocardial infarction to the corresponding supplying coronary arteries.

Materials And Methods: An interactive segmentation of the coronary arteries was performed in MRCA data sets (n=25). The LGE slices were matched onto the vessel segmentation to perform a fused analysis of coronary artery anatomy and LGE.

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Objective: The purpose of this study was (1) to compare 2-dimensional computed tomographic (2D-CT) and 3D-CT computer-assisted preoperative surgical planning, and (2) to define the indications for the latter method.

Background: The determination of functional residual liver volumes and the imaging of intrahepatic anatomy are critical when planning complex liver resections.

Patients And Methods: Prospective study of 202 consecutive patients who underwent high-risk procedures (extended right/left hepatectomies, central resections, polysegmentectomies, large atypical resections, repeated resections, and hepatectomies in the setting of abnormal liver parenchyma).

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