Publications by authors named "Peiqun Xu"
Proc Natl Acad Sci U S A
July 2024
Article Synopsis
- The study highlights the importance of nutrient sensing in the placenta for healthy pregnancy and fetal growth, focusing on how the placenta adapts to low nutrient levels.
- It reveals that the transcription factor TFEB plays a crucial role in the differentiation of trophoblasts into syncytiotrophoblasts (STBs), which are vital for maternal-fetal interactions during pregnancy.
- Disruption of TFEB leads to impaired STB formation and severe developmental issues, establishing TFEB as a key player in linking nutrient sensing to trophoblast differentiation.
