Publications by authors named "Peiqin Liang"
Article Synopsis
- Ovarian cancer is often diagnosed too late, with over 70% of cases at an advanced stage, leading to poor outcomes; MRI is the best preoperative assessment tool, while cisplatin-based chemotherapy is the standard treatment.
- A new technique uses nanoparticles (HA@PFG NPs) made from a cisplatin prodrug (Pt-COOH), iron, and natural polyphenols (Gossypol) to enhance drug delivery and release at tumor sites, allowing for controlled drug release and effective treatment.
- Experimental results show that HA@PFG NPs can reduce tumor activity in a patient-derived model and work through specific signaling pathways, suggesting a promising integrated approach of MRI and
Ovarian cancer (OC) is one of the most common and recurring malignancies in gynecology. Patients with relapsed OC always develop "cascade drug resistance" (CDR) under repeated chemotherapy, leading to subsequent failure of chemotherapy. To overcome this challenge, amphiphiles (P1) carrying a nitric oxide (NO) donor (Isosorbide 5-mononitrate, ISMN) and high-density disulfide are synthesized for encapsulating mitochondria-targeted tetravalent platinum prodrug (TPt) to construct a nanocomposite (INP@TPt).
View Article and Find Full Text PDFObjective: To evaluate the effect of a comprehensive rehabilitation programme on closure of the rectus diastasis (RD) and quality of life in women after delivery.
Design: A randomised controlled trial with blinded assessment.
Setting: A tertiary hospital and participants' homes in Foshan, China.
Background: The 2019 coronavirus disease (COVID-19) is a public health emergency of international concern. To date, there are limited studies that have investigated the impact of COVID-19 pandemic on mental health among female population. Therefore, the study aims to investigate the prevalence of postpartum depression (PPD) and it's related factors among women in Guangzhou, China, during the COVID-19 pandemic.
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