Publications by authors named "Peimin Bian"
Identifying mineral decrement with bone injury by quantifying osteocalcin on current-volt sensor.
Biotechnol Appl Biochem
October 2022
Article Synopsis
- Osteoporosis is a bone disease characterized by weakened bones and increased fracture risk, but traditional diagnostic methods are costly and complicated.
- A new point-of-care system has been developed that uses a sensor to detect osteocalcin, a biomarker for bone metabolism, which allows for easier diagnosis.
- The sensor shows a high sensitivity for osteocalcin with a detection limit of 100 pg/ml and confirmed specificity, making it a promising tool for identifying osteoporosis conditions.
Evaluation of antiarthritic activity of nimbolide against Freund's adjuvant induced arthritis in rats.
Artif Cells Nanomed Biotechnol
December 2019
Nimbolide, a triterpenoid isolated from flower of neem tree possess various therapeutic properties. The objective of the study was to assess the anti-arthritic activity of nimbolide in arthritis induced rats. Nimbolide (20 mg/kg per day) was given orally to arthritic rats induced with Complete Freund's Adjuvant and changes in paw volume, body weight, organ indices (thymus and spleen), arthritic score, biochemical parameters and proinflammatory cytokines levels were determined.
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