Publications by authors named "Peiliang He"
Enocyanin (ENO), an anthocyanin extracted from grapes, has been shown to exert inhibitory effects on acid phosphatase and inflammation; however, its role in osteogenesis and bone formation is currently unknown. The present study aimed to investigate the effects of ENO on osteogenesis and bone formation , and to explore the rudimentary mechanisms. KusaO cells were employed to evaluate the osteogenic role of ENO by Alizarin red S staining, ALP staining, quantitative PCR and western blotting, and an analysis of the therapeutic effects of ENO on a femoral fracture model was performed using stereo microscope, micro‑CT and histological staining.
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- Aging is closely linked to various diseases, with osteoporosis being a common age-related condition affecting older adults.
- The senescence-related secretory phenotype (SASP) plays a role in transmitting aging information through extracellular vesicles (EVs), which connect micro-environmental aging to age-related diseases.
- The article aims to explore how EVs contribute to the mechanisms of aging cells in osteoporosis, offering insights into its occurrence, progression, and potential prevention or treatment strategies.
The role of triclosan-coated suture in preventing surgical infection: A meta-analysis.
Jt Dis Relat Surg
January 2023
Article Synopsis
- The meta-analysis aimed to compare the effectiveness of triclosan-coated sutures versus uncoated sutures in preventing surgical site infections (SSIs) after hip and knee replacement surgeries.
- The study included three randomized-controlled trials (RCTs) with 2,689 patients, finding a lower overall SSI incidence in the triclosan group (1.9%) compared to the control group (2.5%), but this difference was not statistically significant.
- The conclusion indicates that triclosan sutures did not significantly reduce SSI rates compared to uncoated sutures, highlighting the need for further high-quality RCTs to explore the issue more comprehensively.
Background: Osteoporotic vertebral compression fracture (OVCF) is one of the most common fragile fractures, and percutaneous vertebroplasty provides considerable long-term benefits. At the same time, there are many reports of postoperative complications, among which fracture after percutaneous vertebroplasty is one of the complications after vertebroplasty (PVP). Although there are many reports on the risk factors of secondary fracture after PVP at home and abroad, there is no systematic analysis on the related factors of secondary fracture after PVP.
View Article and Find Full Text PDFObjective: Fibrocartilage transition zone (FC) is difficult to regenerate after surgical re-attachment of tendon to bone. Here, we investigated whether type II collagen-sponges (CII-sponges) facilitated tendon stem/progenitor cells (TSPCs) to adopt chondrogenic phenotypes and further observed if this material could increase the FC areas in bone-tendon junction (BTJ) injury model.
Methods: CII-sponges were made as we previously described.