Background: This study aims to explore the effects of the iris-ciliary angle (ICA) on the accurate prediction of the vault after implantable collamer lens (ICL) using the manufacturer's online calculation and ordering system (OCOS).
Methods: The participants were categorized into three groups according to the size of ICA as follows: narrow ICA group (< 40°); normal ICA group (40°-60°); wide ICA group (> 60°). We compared the preoperative ocular characteristics and postoperative vault at 3 months among the three groups.
Background: To assess the relationship between postoperative implantable collamer lens (ICL) vault and lens height obtained from two different measurements.
Methods: A retrospective case series study enrolled eyes with horizontally implanted ICL. Crystal lens rise (CLR) and the distance between STS plane and anterior crystalline lens surface (STSL) were measured in the horizontal and vertical directions using ultrasound biomicroscopy (UBM).
The scarcity of corneal tissue to treat deep corneal defects and corneal perforations remains a challenge. Currently, small incision lenticule extraction (SMILE)-derived lenticules appear to be a promising alternative for the treatment of these conditions. However, the thickness and toughness of a single piece of lenticule are limited.
View Article and Find Full Text PDFAim: To investigate the early changes in dry eye symptoms, tear function and ocular surface following small-incision lenticule extraction (SMILE) for myopia.
Methods: Ninety-seven consecutive patients (193 eyes) who underwent SMILE for myopia were observed in this longitudinal and retrospective study. Parameters evaluated included: subjective dry eye symptoms (dryness, foreign body sensation and photophobia), tear film breakup time (TBUT), Schirmer I test (S I T) without anesthesia, tear meniscus height (TMH) and corneal fluorescein staining.
Background: To investigate the molecular defects in a four-generation Chinese pedigree affected with Thiel-Behnke corneal dystrophy (TBCD). And to further study the relationship between genetic mutation and clinical manifestations.
Methods: Individuals of the pedigree were recruited for extensive ophthalmic examinations.
Objective: To investigate the role of caspase-3 and its inhibitor Ac-DEVD-CHO in rat lens epithelial cell apoptosis induced by hydrogen peroxide (H(2)O(2)) in vitro.
Methods: Rat lenses were incubated in modified Eagle's medium containing 2 mmol/L H(2)O(2) to induce apoptosis in vitro. Apoptosis in lens epithelial cells was assessed by transmission electron microscopy and annexin V-propidium iodide (PI) double staining flow cytometry after 12, 24 and 48 h of incubation.
Objective: To investigate the expression of vascular endothelial growth factor (VEGF) in rat cornea after cautery with alkali.
Methods: In Sprague-Dawley rats, inflammatory corneal neovascularization was induced by cautery with alkali. VEGF was detected in corneal samples at different times by Western-blot, and immunohistochemistry method was used to investigate the distribution of VEGF at rat cornea after cautery with alkali.
Objective: To study the expression and role of calpain II in rat lens epithelial cells (LECs) of hydrogen peroxide (H(2)O(2))-induced cataract.
Methods: Rat lenses were cultured in vitro and cataract was induced by 2 mM H(2)O(2). The lenses were observed under microscope.