Energy optimisation for the combination of turning and drilling features using differential evolution.

Cutting parameter optimisation is an effective way to realise energy-efficient machining. In previous studies, the cutting parameters of machining features of turning, milling, grinding, drilling, hobbing, and threading were optimised to decrease energy consumed by machine tools, and considerable energy savings were achieved. However, the energy consumption (EC) for each feature was separately optimised without systematic consideration of the negative effects on the EC for other features.

Evaluating vehicular exhaust and evaporative emissions via VOC measurement in an underground parking garage.

Vehicular emissions, including both tailpipe exhaust and evaporative emissions, are major anthropogenic sources of volatile organic compounds (VOCs) in urban cities. Current knowledge on vehicle tailpipe and evaporative emissions was mainly obtained via laboratory tests on very few vehicles under experimental conditions. Information on fleet gasoline vehicles emission features under real-world conditions is lacking.

Efficacy of synchronous stereotactic radiotherapy with temozolomide combined with whole brain radiotherapy in treating brain metastases originating from non-small cell lung cancer.

Purpose: To investigate the efficacy and safety of synchronous stereotactic radiotherapy (SRT) with temozolomide (TMZ) combined with whole brain radiotherapy (WBRT) in treating brain metastases originating from non-small cell lung cancer (NSCLC).

Methods: The clinical data of 128 patients with brain metastases originating from NSCLC treated in the hospital from August 2015 to August 2017 were retrospectively analyzed. Among these patients, 64 received synchronous SRT with TMZ+WBRT (TMZ group), and 64 underwent SRT+WBRT (radiotherapy group).

Downregulation of lncRNA-HEIH curbs esophageal squamous cell carcinoma progression by modulating miR-4458/PBX3.

Background: Long non-coding RNAs (lncRNAs) have been found to play a specific part in the development of esophageal squamous cell carcinoma (ESCC), except for lncRNA HEIH. Here, we aimed to discover the molecular mechanisms of HEIH in ESCC.

Methods: We detected the expression level of HEIH and miR-4458 in ESCC tissues and cells using qRT-PCR assay.

MicroRNA-498 inhibits the proliferation, migration and invasion of gastric cancer through targeting BMI-1 and suppressing AKT pathway.

Recently, microRNA-498 (miR-498) plays important effect in human cancers. Nonetheless, the role of miR-498 is still unclear in gastric cancer (GC). Therefore, this study was designed to investigate the function of miR-498 in GC tissues and cell lines (SGC-7901, BGC-823, MGC-803).

Antimicrobial potential of endophytic fungi from .

The purpose of the present study was to discover antimicrobial endophytic fungi from Three fungal endophytes with antibacterial activity were isolated and determined as sp. HQ-1, sp. HQ-7 and sp.

Optical Surface Management System for Patient Positioning in Interfractional Breast Cancer Radiotherapy.

Background: The Optical Surface Management System (OSMS) is a simple, fast, reproducible, and accurate solution for patient set-up and can minimize random day-to-day set-up errors. However, studies in breast cancer patients are rare.

Objective: To analyze 200 patient set-ups in 20 patients with breast cancer by comparing the OSMS with the conventional cone-beam computed tomography (CBCT).

Modified Glasgow Prognostic Score at Recurrence Predicts Poor Survival in Resected Non-Small Cell Lung Cancer (NSCLC) Patients.

BACKGROUND The purpose of this study was to investigate the impact of the modified Glasgow Prognostic Score (GPS) at the time of recurrence on post-recurrence survival (PRS) in non-small cell lung cancer (NSCLC) patients after surgical resection. MATERIAL AND METHODS The clinicopathologic characteristics and outcome data of 266 patients with recurrent NSCLC were collected and reviewed retrospectively. The prognostic impact of mGPS at recurrence in patients with recurrent NSCLC was investigated in univariate and multivariate analyses.

Small interfering RNA (siRNA) against Slug induces apoptosis and sensitizes human anaplastic thyroid carcinoma cells to doxorubicin.

Objective: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human cancers and often shows resistance to multimodal therapeutic approaches. It has been shown that the transcriptional repressor Slug inhibits the chemotherapeutic agent-induced apoptosis of cancer cells. We evaluated whether targeting of Slug could augment doxorubicin (DOX)-induced apoptosis of ATC cells.