Publications by authors named "Peihong Lyu"
Antioxidants (Basel)
April 2024
Article Synopsis
- Cannabis and its major cannabinoid, cannabidiol (CBD), show potential anticancer effects against skin tumors, particularly melanoma.
- In experiments, CBD exhibited significant cytotoxicity, with IC values of 28.6 and 51.6 μM against murine (B16F10) and human (A375) melanoma cells, respectively.
- Synthetic CBD derivatives with bipiperidinyl groups demonstrated even greater cytotoxicity, suggesting that these compounds could be effective in treating melanoma by inducing apoptosis in cancer cells.
