Publications by authors named "Peidong Zhang"

Objective: Polytrauma is a complex condition associated with poor outcomes and high mortality rates resulting from severe damage and complicated complications. This study sought to ascertain the incidence of chronic complications in polytrauma patients, as well as the early immune changes and risk factors.

Methods: A multicenter, prospective and observational cohort study was conducted at the emergency surgery or traumatic intensive care unit (TICU) of the Advanced Trauma Center from August 2020 to July 2023.

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Article Synopsis
  • Polytrauma, defined as severe multiple traumatic injuries, was investigated to determine its frequency and specific risk factors for recidivism, rather than just being labeled a random accident.
  • A study conducted across four Advanced Trauma Centers from August 2020 to July 2023 analyzed 2,490 trauma patients, using logistic regression to identify factors that contribute to repeated polytrauma incidents.
  • Results showed a high recidivism rate of 44.6%, with recidivists mostly being males aged 45-54, experiencing more severe injuries in subsequent events, and linked to factors like sleep deprivation and occupations in construction or delivery.
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As a plant-specific gene family, class III peroxidases (PODs) play an important role in plant growth, development, and stress responses. However, the POD gene family has not been systematically studied in . In this study, a total of 57 genes were identified in the genome.

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The utilization of plant growth-promoting rhizobacteria (PGPR) holds great promise for the restoration of damaged terrestrial plant ecosystems. However, there is a significant knowledge gap regarding the application of PGPR in rehabilitating aquatic ecosystems. In this study, we conducted a mesocosm experiment to investigate the effects of Raoultella ornithinolytica F65, Pantoea cypripedii G84, Klebsiella variicola G85, Novosphingobium profundi G86, and Klebsiella pneumoniae I109 on eelgrass (Zostera marina L.

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Background: Higher greenness was associated with a lower risk of adult mortality. However, the effects of greenness on the mortality of infant and child under-5 have not been fully examined.

Objectives: The association of greenness on the infant mortality rate (IMR) and child under-5 mortality rate (U5MR) in 147 Chinese cities from 2009 to 2020 was evaluated.

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  • This study investigates how regular fish oil supplementation affects the risk of developing hypertension and considers if genetic factors play a role in this association.
  • The research analyzed data from over 213,000 participants, finding that those who regularly used fish oil had a lower risk of new-onset hypertension compared to non-users, especially among those with higher genetic susceptibility.
  • The findings suggest that regular fish oil supplementation may be particularly beneficial for individuals genetically predisposed to hypertension, potentially reducing their risk by a significant margin.
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  • This study investigates Acute Gastrointestinal Injury (AGI) in elderly polytrauma patients, revealing a high occurrence (73.5%) among this population.
  • It identifies key risk factors associated with AGI, such as increasing Injury Severity Score (ISS), serum lactate, and a decreased Glasgow Coma Scale (GCS).
  • Lastly, the study highlights the significantly higher mortality rates in elderly patients with AGI (40.4% at 28 days and 61.2% at 60 days), emphasizing the need for careful monitoring and predictive assessments.
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Mechanics shape cell and tissue plasticity and maintain their homeostasis. In cancers, mechanical signals regulate cancer hallmarks via mechanotransduction pathways, such as proliferation, metastasis and metabolic reprogramming. However, comprehensive characterization of mechanotransduction pathway genes and their clinical relevance across different cancer types remains untouched.

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Introduction: The study aimed to investigate the associations of changes in social isolation, loneliness, or both, with cognitive function.

Methods: Data were from 7299 older adults in the Chinese Longitudinal Healthy Longevity Survey. We defined four change patterns (no, incident, transient, and persistent) for social isolation and loneliness, and created nine-category variable to represent the joint changes.

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Multi-stable structures attract great interest because they possess special energy landscapes with domains of attraction around the stable states. Consequently, multi-stable structures have the potential to achieve prescribed reconfiguration with only a few lightweight actuators (such as shape-memory alloy springs), and do not need constant actuation to be locked at a stable state. However, most existing multi-stability designs are based on assembling bi-stable unit cells, which contain multitudes of distractive stable states, diminishing the feasibility of reconfiguration actuation.

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Ambient air pollution is a major global health concern. Yet, no study has thoroughly assessed its link to respiratory mortality. Our research evaluated the combined and individual effects of air pollutants on respiratory mortality risks based on the UK Biobank.

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The contaminant status, spatial distribution, partitioning behavior, and ecological risks of 26 legacy and emerging perfluoroalkyl and polyfluoroalkyl substances (PFASs) in Laizhou Bay, China were investigated. The concentrations of ∑PFASs in surface and bottom seawater ranged from 37.2 to 222 ng/L and from 34.

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Frame Transplantation System (FTS) is considered an efficient method for seagrass restoration, but the effect of the rusting of iron frame on seagrass restoration remains unclear. We transplanted Zostera marina plants using iron FTS treated with fluorocarbon paint (painted treatment, PT) and traditional unpainted iron FTS (unpainted treatment, UT) under controlled mesocosm conditions for 24 days. Our results showed that the survival rate of Z.

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Despite progress in the application of checkpoint immunotherapy against various tumors, attempts to utilize immune checkpoint blockade (ICB) agents in triple negative breast cancer (TNBC) have yielded limited clinical benefits. The low overall response rate of checkpoint immunotherapy in TNBC may be attributed to the immunosuppressive tumor microenvironment (TME). In this study, we investigated the role of mitogen-associated kinase TTK in reprogramming immune microenvironment in TNBC.

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What Is Already Known About This Topic?: The relationship between specific dietary patterns and dietary diversity with cognitive frailty continues to be a subject of ambiguity.

What Is Added By This Report?: This research revealed that regular consumption of fruit, meat, bean products, garlic, and tea was connected to a decreased risk of cognitive frailty. Compared to participants with dietary diversity score (DDS) ≤6 points, those with DDS of 9-10, 11-12, and ≥12 had a lower risk of cognitive frailty.

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Purpose: Resection beyond the contrast-enhanced zone contributed to reduce tumor burden and prolong survival in glioblastomas. The optimal extent of resection (EOR) and how to achieve it are worthy of continuous investigation for obtaining a satisfactory balance between maximal resection and the preservation of neurological function.

Methods: A total of 340 adult supratentorial lobar glioblastomas (included astrocytoma, WHO 4, IDH mutation and glioblastoma) were retrospectively evaluated.

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Article Synopsis
  • A study with 367,978 participants found that both air pollution and lack of physical activity (PA) contribute to a higher risk of developing chronic kidney disease (CKD).
  • Higher levels of fine particulate matter and nitrogen oxides increased CKD risk by 11-15%, while moderate and high PA levels reduced this risk by 18% and 22%, respectively.
  • The results suggest that increasing physical activity can help prevent CKD regardless of air pollution levels, indicating the need for further research in polluted areas.
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Evidence for the effects of dietary diversity changes and cognitive frailty (CF) in the older adults is not clear. This study aimed to investigate the relationship between dietary diversity changes and CF in older adults Chinese. A total of 14,382 participants (mean age: 82.

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Backgrounds: Gliomas is a deadly disease without effective therapy. Although immunotherapy has provided novel choices for glioma treatment, the curative efficacy is unsatisfactory due to the complex immune micro-environment and the heterogeneity of the disease. Therefore, it is urgent to identify effective biomarkers and therapeutic targets.

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Female sex workers (FSWs) are considered a high-risk group for sexually transmitted infections (STIs). However, limited data exist on the prevalence and trends of HIV, syphilis and HCV among FSWs in the Sino-Vietnam border area. To determine the prevalence, trends and correlates of STIs among Chinese local FSWs (CL-FSWs) and cross-border migrant FSWs (CM-FSWs), we conducted consecutive cross-sectional surveys from 2016 to 2021, recruiting 7747 CL-FSWs and 932 CM-FSWs.

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The association between long-term joint exposure to all kinds of ambient air pollutants and the risk of mortality is not known. Our study prospectively assessed the joint associations of various air pollutants with cause-specific and all-cause mortality risk and identified potential modifying factors affecting these associations. A total of 400,259 individuals aged 40-70 years were included in this study.

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Background: Little is known about the combined relationship between night shifts and lifestyle risks with incident dementia or their potential interactions. To evaluate the association of night shifts and lifestyle risks with incident dementia and further analyze their interactions.

Methods: A total of 276 059 participants were included in this study from the UK Biobank cohort.

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